A5108773399- Acute Kidney Injury Research
- Autoimmune and Inflammatory Disorders Research
- Parvovirus B19 Infection Studies
- COVID-19 Clinical Research Studies
- Pancreatitis Pathology and Treatment
- Hematological disorders and diagnostics
- Chronic Kidney Disease and Diabetes
- Sepsis Diagnosis and Treatment
- Immune Cell Function and Interaction
- Respiratory viral infections research
- Long-Term Effects of COVID-19
- Parathyroid Disorders and Treatments
- Complement system in diseases
- Acute Myocardial Infarction Research
- Blood groups and transfusion
- Acute Ischemic Stroke Management
- Influenza Virus Research Studies
- Pharmacological Effects of Natural Compounds
- Cardiac Arrest and Resuscitation
- Neonatal Health and Biochemistry
- Health Systems, Economic Evaluations, Quality of Life
- Venous Thromboembolism Diagnosis and Management
- Peripheral Neuropathies and Disorders
- Cardiomyopathy and Myosin Studies
- COVID-19 and healthcare impacts
Peking University
2012-2025
Peking University People's Hospital
2012-2025
Institute of Electrical and Electronics Engineers
2022
Gorgias Press (United States)
2022
Weatherford College
2021
Creative Research Enterprises (United States)
2018
National Defense Medical Center
2015
First Affiliated Hospital of Henan University of Science and Technology
2009-2014
Stomatology Hospital
1969
Sun Yat-sen University
1969
Ceftriaxone is widely used in clinical practice for its efficacy against infections. However, increasing association with life-threatening immune hemolytic reactions urge clinicians to enhance recognition and maintain sharp vigilance. This report details a rare severe case of ceftriaxone-induced anemia (CIHA), hemodynamic instability crisis 54-year-old woman after intravenous infusion ceftriaxone following respiratory infection. Clinicians must promptly identify symptoms suggestive CIHA,...
Acute kidney injury (AKI) is a serious and fatal complication of acute myocardial infarction (AMI). It has high short- long-term mortality rates poor prognosis but potentially preventable. However, the current incidence, risk factors, outcomes AKI in Chinese population are not well understood would serve first step to identify high-risk patients who could receive preventative care.The medical data 1124 hospitalized diagnosed with AMI from October 2013 September 2015 were reviewed. was...
Abstract The new outbreak of Coronavirus Disease 2019 (COVID-19) has emerged as a serious global public health concern. A more in-depth study blood coagulation abnormality is needed. We retrospectively analyzed 147 consecutive patients with COVID-19 who were admitted to three ICUs in Wuhan from February 9th, 2020 March 20th, 2020. baseline and other characteristics studied. Our results showed that the prolonged PT, FDP, DD positively correlated levels neutrophils, ferritin, LDH, total...
Abstract Background Acute kidney injury (AKI) is a common and critical complication of sepsis, associated with unacceptable morbidity mortality. Current diagnostic criteria for AKI was insensitive early detection. Novel biomarkers including cystatin C, molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), klotho fibroblast growth factor-23 (FGF-23) can predict earlier allow immediate interventions. We aimed to determine the performance these detecting in sepsis patients....
Nanomechanical behaviors of single living cardiomyocytes are quantitatively observed using calculated torsions and deflections an AFM cantilever. The lateral contractions related to the calcium intensity within rather than vertical beating power cardiomyocytes. Drug-induced nanomechanical changes were further investigated by measuring in real time.
Objective: To evaluate the efficacy and safety of oseltamivir treatment in a population at high risk for influenza.Research design methods: This was randomized, open-label, controlled trial involving Chinese patients with chronic respiratory diseases (chronic bronchitis, obstructive emphysema, bronchial asthma or bronchiectasis) cardiac disease. Patients showing symptoms influenza were randomly assigned to receive oral 75 mg twice daily 5 days (oseltamivir group), symptomatic (control group)...
BACKGROUND: A pandemic of coronavirus disease (COVID-19) has been declared by the World Health Organization (WHO) and caring for critically ill patients is expected to be at core battling this disease.However, little known regarding an early detection high risk fatality. METHODS:This retrospective cohort study recruited consecutive adult admitted between February 8 29, 2020, three intensive care units (ICUs) in a designated hospital treating COVID-19 Wuhan.The detailed clinical information...
Background. Acute kidney injury (AKI) was a common and serious complication in patients with acute myocardial infarction (AMI). Novel biomarkers therapies were deficient imperative for AKI’s early diagnosis therapy after AMI. α-Klotho considered as an biomarker potential AKI recently. Previous studies reported that the expression of decreased rodents, supplement alleviated injury. Nevertheless, its effect has not been studied presenting Methods. A total 155 consecutive diagnosed AMI at...
Background Pulmonary thromboembolism is a common disease frequently encountered in the emergency room and has high mortality rate. Antiphospholipid syndrome (APS) high-risk factor for recurrent pulmonary embolism (PE). It critical to effectively administer anticoagulants avoid recurrence of thrombotic events. This study aims identify clinical characteristics APS patients with PE (APS-PE) develop risk score determining presence situations. Methods We retrospectively enrolled 76 this study, 46...
Introduction: Klotho has emerged as a potential protective factor for cardiovascular diseases recently. Nevertheless, the levels of serum in acute coronary syndrome (ACS) have not been reported. Hence, we undertook study to investigate correlation between and ACS patients. Method: This observational cohort was conducted at Peking University People’s Hospital May 2016 April 2020. Upon admission, collected patients’ clinical data ELISA tests measure their levels. Result: A total 349 patients...
Background Secondary hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disease of immune hyperactivation that arises in the context infectious, inflammatory, or neoplastic triggers. The aim this study was to establish predictive model for timely differential diagnosis original resulting HLH by validating clinical and laboratory findings further improve efficacy therapeutics HLH. Methods We retrospectively enrolled 175 secondary patients study, including 92 with hematologic...
Liver abscess (LA) is a serious medical condition that predisposes patients to sepsis. However, predicting sepsis in LA has rarely been explored. This study employed univariate and multivariate logistic regression analyses identify independent risk factors for sepsis, which would provide guidance clinical diagnosis treatment.
Background: This study aims to determine the clinical characteristics and prognosis of COVID-19 patients with comorbidities identify survival factors. Methods: A retrospective was conducted in Wuhan, China, between February 8, 2020, March 9, 2020. Based on underlying diseases, were assigned either comorbidity group or non-comorbidity group. The outcomes analyzed a Kaplan-Meier analysis used evaluate predictive value each comorbidity. Results: During period, 278 enrolled, 175 (62.95%) group,...
The aim of this study is to monitor, identify, and compare the adverse events (AEs) related tenecteplase alteplase, with objective exploring potential safety for acute ischemic stroke (AIS) guiding its use enhance patient safety.
BACKGROUND: Elevated troponin I (TnI) is common among trauma patients.TnI an indicator of myocardial injury, but clinical diagnosis blunt cardiac injury cannot be based solely on increase in TnI.Therefore, this study aims to explore the changes and signifi cance serum TnI patients. METHODS:The data consecutive patients admitted our center between July 1, 2017 31, 2020 were retrospectively analyzed.According levels within 24 hours admission, divided into elevated normal groups.According after...