- Inflammatory Bowel Disease
- Microscopic Colitis
- Immunodeficiency and Autoimmune Disorders
- Molecular Biology Techniques and Applications
- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Celiac Disease Research and Management
- Cell Adhesion Molecules Research
- Salmonella and Campylobacter epidemiology
- Pharmaceutical studies and practices
- Proteoglycans and glycosaminoglycans research
- Iron Metabolism and Disorders
- Blood groups and transfusion
- Childhood Cancer Survivors' Quality of Life
- Autoimmune and Inflammatory Disorders
- Reproductive System and Pregnancy
- Hormonal and reproductive studies
- Blood transfusion and management
- Muscle and Compartmental Disorders
- Escherichia coli research studies
- Gut microbiota and health
- Acute Lymphoblastic Leukemia research
- Platelet Disorders and Treatments
- Listeria monocytogenes in Food Safety
Saveetha University
2020
Vellore Institute of Technology University
2019
Central Institute for Research on Buffaloes
2017-2019
Children's Healthcare of Atlanta
2013-2017
Emory University
2012-2017
Gut microbiome dysbiosis has been demonstrated in subjects with newly diagnosed and chronic inflammatory bowel disease (IBD). In this study we sought to explore longitudinal changes ascertain associations between markers of activity treatment outcome. We performed a prospective cohort 19 treatment-naïve pediatric IBD 10 healthy controls, measuring fecal calprotectin assessing the gut via repeated stool samples. Associations clinical characteristics were tested using generalized estimating...
ABSTRACT Background: Iron deficiency and anemia affect up to 50% 75% of patients with inflammatory bowel disease (IBD). in IBD may be difficult diagnose because the effect inflammation on iron status biomarkers. Thus, there is a need for better methods accurately determine IBD. Objective: The aim study was investigate association hemoglobin content reticulocytes (CHr) utility CHr comparison standard Methods: We conducted cross‐sectional children biomarkers (CHr, ferritin, soluble transferrin...
Crohn's disease (CD) is highly heritable. NOD2 has emerged as the main susceptibility gene among individuals of European ancestry; however, does not appear to contribute CD many non-European populations. Today's African American (AA) population represents an admixture West (80%) and (20%) ancestry. Since genotype-based tools are becoming increasingly available for CD, it important that we validate risk variants in different populations, such admixed AAs. We analyzed AAs (n = 321, 240 with...
Abstract Backgrounds Recent studies have identified the role of serologic markers in characterizing disease phenotype, location, complications, and severity among Northern Europeans (NE) with Crohn’s (CD). However, very little is known about serology CD African Americans (AA). Our study explored relationship between phenotype AA CD, while controlling for genetic ancestry. Methods AAs were enrolled as participants through multicenter collaborative efforts. Serological levels IgA...
Laboratory tests can be done on the cellular or fluid portions of blood. The use different blood collection tubes determines portion that analyzed (whole blood, plasma serum). Laboratories involved in studying genetic basis human disorders rely anticoagulated whole collected EDTA-containing vacutainer as source DNA for / genomic analysis. Because most clinical laboratories perform biochemical, serologic and viral testing a first step phenotypic outcome investigation, is also...
Enterohaemorragic Escherichia coli (EHEC) is a pathogenic E.coli which causes diarrhea or haemorrhagic colitis in human beings, may occasionally progress to hemolytic uremic syndrome (HUS).A total of 100 buffalo meat samples (buffen) were processed for finding out the presence enterohaemorrhagic E. (EHEC).Among them, thirty five found positive (35%), yielded 37 isolates belonging 17 different serogroups.However, one strain remained untypable.Further, coli, nine confirmed as EHEC and belonged...