A5101957763- Effects and risks of endocrine disrupting chemicals
- Microplastics and Plastic Pollution
- Privacy-Preserving Technologies in Data
- Air Quality and Health Impacts
- Asthma and respiratory diseases
- Indoor Air Quality and Microbial Exposure
- Medical Image Segmentation Techniques
- Dermatology and Skin Diseases
- Graphene and Nanomaterials Applications
- Cryptography and Data Security
- Explainable Artificial Intelligence (XAI)
- Contact Dermatitis and Allergies
- Topic Modeling
- Cancer, Hypoxia, and Metabolism
- Medical Imaging Techniques and Applications
- biodegradable polymer synthesis and properties
- Cancer-related molecular mechanisms research
- Cancer Research and Treatments
- Pain Management and Treatment
- Access Control and Trust
- Genetics, Aging, and Longevity in Model Organisms
- Advanced Radiotherapy Techniques
- Genomics and Rare Diseases
- Adversarial Robustness in Machine Learning
- Immunotoxicology and immune responses
Central China Normal University
2016-2025
Huazhong University of Science and Technology
2025
Jining Medical University
2025
Google (United States)
2019-2024
Renmin University of China
2023
Jiangnan University
2020-2023
Tianjin University
2022
Kunming University of Science and Technology
2020
University of Pittsburgh
2016
UPMC Hillman Cancer Center
2016
Microplastics and phthalates are prevalent emerging pollutants that pose a potential impact on human health. Previous studies suggest both microplastics can adversely affect the reproductive systems of humans mammals. However, combined these female system remains unclear. Here we show impacts exposure to polystyrene (PS-MPs) di-2-ethylhexyl phthalate (DEHP) Sprague-Dawley rats' systems. We find co-exposure PS-MPs DEHP results in marked increase cystic atretic follicles, oxidative stress,...
Abstract Background Increasing attention is being paid to the environmental and health impacts of nanoplastics (NPs) pollution. Exposure with different charges functional groups may have adverse effects after ingestion by organisms, yet potential ramifications on mammalian blood glucose levels, risk diabetes remain unexplored. Results Mice were exposed PS-NPs/COOH/NH 2 at a dose 5 mg/kg/day for nine weeks, either alone or in T2DM model. The findings demonstrated that exposure PS-NPs modified...
Proline accumulation has been shown to correlate with tolerance drought and salt stresses in plants. We attempt introduce the wild-type, mutant, fusion proBA genes derived from Bacillus subtilis into Arabidopsis thaliana under control of a strong promoter cauliflower mosaic virus 35S (CaMV35S). The transgenic plants produced higher level free proline than overproduction resulted increased osmotic stress Besides, mutation genes, which were proved lead <TEX>$\alpha$</TEX>-glutamyl kinase...
Abstract Background Cardiac shock wave therapy (CSWT) improves cardiac function in patients with severe coronary artery disease (CAD). We aimed to evaluate the clinical outcomes of a new CSWT treatment regimen. Methods The 55 CAD were randomly divided into 3 groups. control group ( n = 14) received only medical therapy. In A 20), was performed times within months. B 21), underwent sessions/week, and 9 sessions completed 1 month. Primary outcome measurement 6-minute walk test (6MWT). Other...
To improve real-world applications of machine learning, experienced modelers develop intuition about their datasets, models, and how the two interact. Manual inspection raw data - representative samples, outliers, misclassifications is an essential tool in a) identifying fixing problems data, b) generating new modeling hypotheses, c) assigning or refining human-provided labels. However, manual problematic for privacy sensitive such as those representing behavior individuals. Furthermore,...
Safe and effective therapeutic management of refractory coronary artery disease (CAD) in heart patients is critical to enhance cardiovascular function improve quality life. Current therapies for CAD are inadequate ameliorating angina promoting revascularization ischemic myocardium.Cardiac shock wave therapy (CSWT) a safe noninvasive intervention the with CAD.The study enrolled 9 male age 50 70 years (5.11 ± 5.46 years) diagnosis stent implantation (3.00 2.24 stents). CSWT was carried out 3...
Dibutyl phthalate (DBP) is mainly taken up by the general population from food intake. To estimate intake of phthalates, determining distribution and accumulation DBP in biological materials was a critical need. In this work, we set two novel approaches with monoclonal antibody specific to determine vivo. The contents liver, kidney, stomach testes were detected immunofluorescence assays indirect competitive ELISA. This data give directly evidence that indicates Double-label assay provides...
Several epidemiological studies have suggested a possible link between exposure to Diisononyl phthalate (DINP) and the development of allergies. These findings remain controversial since there is insufficient scientific evidence assess ability DINP influence allergic immune responses. In addition, mechanisms behind DINP-caused diseases not been fully elucidated. this study, Balb/c mice were orally exposed for 3 weeks then sensitized with fluorescein isothiocyanate (FITC). We showed that oral...
Autoimmune thyroid disease (AITD) is the most common autoimmune that causes hypothyroidism. High iodine a well-known factor can induce disorders, including Hashimoto's thyroiditis, one of main types AITD. Recent epidemiological studies have indicated phthalates, especially di-n-butyl phthalate (DBP) may disease. In this study, we aim to determine effects and underlying mechanisms high and/or DBP exposure on Female Wistar rats were modeled with thyroglobulin exposed DBP. We investigated...
Chronic lymphocytic thyroiditis (CLT) is a common autoimmune disorder. The possible pathogenic role and mechanism of dibutyl phthalate (DBP) in CLT still controversial. Experiments were conducted after 35-days oral exposure to the three concentrations DBP or saline, immunizations with thyroglobulin (TG). Healthy female Wistar rats randomly divided into ten groups (n = 8 each): (A) saline control, (B) 0.5 mg/kg/d DBP, (C) 5 (D) 50 (E) TG-immunized group, (F) TG- combined (G) (H) (I) plus 100...