Tom Dymond
A5014738117- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intensive Care Unit Cognitive Disorders
- COVID-19 and healthcare impacts
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Contact Dermatitis and Allergies
- Kawasaki Disease and Coronary Complications
- Clostridium difficile and Clostridium perfringens research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Respiratory and Cough-Related Research
- Clinical Nutrition and Gastroenterology
- Gut microbiota and health
- Advanced Chemical Sensor Technologies
- Pharmacological Effects and Assays
- Healthcare cost, quality, practices
- Drug-Induced Adverse Reactions
- Pneumonia and Respiratory Infections
- Diabetes Treatment and Management
- Mechanical Circulatory Support Devices
- Infection Control and Ventilation
Cambridge University Hospitals NHS Foundation Trust
2013-2024
Addenbrooke's Hospital
2021
SARS-CoV-2 is notable both for its rapid spread, and the heterogeneity of patterns transmission, with multiple published incidences superspreading behaviour. Here, we applied a novel network reconstruction algorithm to infer viral transmission occurring between patients health care workers (HCWs) in largest clusters COVID-19 infection identified during first wave epidemic at Cambridge University Hospitals NHS Foundation Trust, UK. Based upon dates individuals reporting symptoms, recorded...
Polyethylene glycol (PEG) is the excipient found in mRNA COVID-19 vaccines. We previously demonstrated PEG allergy was a cause of severe anaphylaxis to Pfizer/BioNTech vaccine. widely used many household products, cosmetics and medicines. However rare, there have been few confirmed cases allergy. The potential concern AstraZeneca vaccine polysorbate 80 (PS80). Cross-reactivity between has suggested, based on their composition skin-test data. aim this study determine whether PEG-allergic...
Abstract Identifying linked cases of infection is a critical component the public health response to viral infectious diseases. In clinical context, there need make rapid assessments whether have arrived independently onto ward, or are potentially via direct transmission. Viral genome sequence data great value in making these assessments, but often not only form available. Here, we describe A2B-COVID, method for identification COVID-19 designed settings. Our combines knowledge about...
Two-thirds of small-bowel transplantation (SBT) recipients develop bacteremia, with the majority infections occurring within 3 months post-transplant. Sepsis-related mortality occurs in 31% patients and is commonly caused by bacteria gut origin, which are thought to translocate across implanted organ. Serial post-transplant surveillance endoscopies provide an opportunity study whether composition ileal colonic microbiota can predict emergence as well pathogen subsequent clinical SBT patient...
Abstract Face masks and personal respirators are used to curb the transmission of SARS-CoV-2 in respiratory droplets; filters embedded some protective equipment could be as a non-invasive sample source for applications, including at-home testing, but information is needed about whether suited capture viral particles detection. In this study, we generated inactivated virus-laden aerosols 0.3–2 microns diameter (0.9 µm mean by mass) dispersed aerosolized onto electrostatic face mask filters....
Objectives To analyse enrolment to interventional trials during the first wave of COVID-19 pandemic in England and describe barriers successful recruitment circumstance a further or future pandemics. Design We analysed registered trial data concurrently did prospective observational study hospitalised patients with who were being assessed for eligibility one RECOVERY, C19-ACS SIMPLE trials. Setting Interventional from clinicaltrials.gov International Standard Randomized Controlled Trial...
Abstract Identifying linked cases of infection is a key part the public health response to viral infectious disease. Viral genome sequence data great value in this task, but requires careful analysis, and may need be complemented by additional types data. The Covid-19 pandemic has highlighted urgent for analytical methods which bring together sources inform epidemiological investigations. We here describe A2B-COVID, an approach rapid identification coronavirus infection. Our method combines...
SARS-CoV-2 is notable both for its rapid spread, and the heterogeneity of patterns transmission, with multiple published incidences superspreading behaviour. Here, we applied a novel network reconstruction algorithm to infer viral transmission occurring between patients health care workers (HCWs) in largest clusters COVID-19 infection identified during first wave epidemic at Cambridge University Hospitals NHS Foundation Trust, UK. Based upon dates individuals reporting symptoms, recorded...