A5071287367- Clinical Nutrition and Gastroenterology
- Organ Transplantation Techniques and Outcomes
- Organ and Tissue Transplantation Research
- Liver Disease and Transplantation
- Nutrition and Health in Aging
- Renal Transplantation Outcomes and Treatments
- Mycobacterium research and diagnosis
- Soft tissue tumor case studies
- Transplantation: Methods and Outcomes
- Tumors and Oncological Cases
- Cancer Diagnosis and Treatment
- Patient Safety and Medication Errors
- Biomedical Ethics and Regulation
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Gastric Cancer Management and Outcomes
- Central Venous Catheters and Hemodialysis
- Esophageal and GI Pathology
- Hypertrophic osteoarthropathy and related conditions
- Gastrointestinal motility and disorders
- Virology and Viral Diseases
- Childhood Cancer Survivors' Quality of Life
- Vascular Malformations and Hemangiomas
- Medical Education and Admissions
- Metastasis and carcinoma case studies
Cambridge University Hospitals NHS Foundation Trust
2014-2024
Addenbrooke's Hospital
2014-2024
University Hospital Southampton NHS Foundation Trust
2017-2023
University of Cambridge
2018-2023
University Gastroenterology
2022
NIHR Southampton Biomedical Research Centre
2019
British Society for Haematology
2017
Gartnavel General Hospital
2007
Western Regional Hospital
1965
University of St Andrews
1965
Although the pathogenesis of multiple sclerosis remains obscure, much pathological and clinical evidence suggests an infective agent as a possible aetiological factor. If such is responsible for initiating disease it seems probable that there latent period several years before develop ment features sclerosis. By time might be impossible to obtain laboratory incriminating organism. However, if remained in central nervous system provide constant anti genic stimulus manifesting itself high...
Background. Desmoid tumors are fibroblastic lesions which often have an unpredictable and variable clinical course. In the context of familial adenomatous polyposis (FAP), these frequently occur intra-abdominally, especially in small-bowel mesentery resulting sepsis, fistulation, invasion abdominal wall retroperitoneum. selected cases where other modalities failed, most radical option is to perform a total enterectomy intestinal transplantation (ITx). this study, we present our center’s...
Two-thirds of small-bowel transplantation (SBT) recipients develop bacteremia, with the majority infections occurring within 3 months post-transplant. Sepsis-related mortality occurs in 31% patients and is commonly caused by bacteria gut origin, which are thought to translocate across implanted organ. Serial post-transplant surveillance endoscopies provide an opportunity study whether composition ileal colonic microbiota can predict emergence as well pathogen subsequent clinical SBT patient...
Compared with other medical specialties, there are lower numbers of female trainees and rates flexible working in gastroenterology. This study aims to examine the experience male understand specialty demographics training.Gastroenterology training data were obtained from British Society Gastroenterology (BSG) trainee surveys 2014, 2018 2020, Royal College Physicians Medical Workforce unit between 2011 2019. Data on endoscopy measures 2021 Joint Advisory Group (JAG) gastrointestinal...
Background and study aims Colonic polypectomy is acknowledged to be a technically challenging part of colonoscopy. Training in recognized often inconsistent. This aimed ascertain worldwide practice training. Patients methods An electronic survey was distributed endoscopic trainees trainers 19 countries asking about their experiences receiving delivering Participants were also asked whether formal training guidance existed country. Results Data obtained from 610 colonoscopists. Of these...
Antifungal agents are routinely used in the post-transplant setting for both prophylaxis and treatment of presumed proven fungal infections. Micafungin is an echinocandin-class antifungal with broad cover favorable side effect profile but, notably, it has no activity against molds order Mucorales. A 47-year-old woman underwent multivisceral transplantation intestinal failure-associated liver disease. She had a prolonged post-operative recovery complicated by invasive candidiasis developed...
Background Several authors have studied the transition from medical student to junior doctor. There been several problems identified, one being prescribing. Junior doctors found be cause of most prescription errors in hospitals. These suggest improvements prescribing teaching, and describe their own innovations seeking correct these problems. Context As a district general hospital UK we had opportunity provide teaching small groups final-year students. We recently begun working as Foundation...
Abstract Introduction This study reports the incidence of chronic kidney disease (CKD) after intestinal transplant (IT) at a single, adult center in United Kingdom. Methods A retrospective review IT was undertaken. renal function assessment pre‐transplant were compared. Post‐transplant and sparing strategies analyzed. Results There 30% variation ( p < .001) estimated glomerular filtration rate (eGFR) normalized GFR assessment. In first 3 months post‐transplant, there 40% decline eGFR...
A 44 year old female with a history of superior mesenteric vein (SMV) thrombosis attributed to the oral contraceptive pill, on parenteral nutrition (PN) resulting intestinal failure-associated liver disease (IFALD) underwent liver/ small bowel transplant. Approximately 6 months post op, she developed new onset back pain and leg weakness. MRI confirmed spondylodiscitis T11-T12 spinal cord compression. Neurosurgical intervention took place immediate decompression. Bone biopsy intra operatively...
Aim of the study: Intestinal transplantation (IT) is a life-saving procedure for carefully selected patients with intestinal failure. We evaluated who had undergone simultaneous and kidney (SIKT) to determine whether UK guidelines inclusion renal allograft (dialysis dependent or estimated glomerular filtration rate ((eGFR)) < 45 ml/min/1.73 m2) are justified. Methods: A single centre analysis was undertaken adults undergoing IT at Cambridge Transplant Centre between December 2007 January...
<h3>Introduction</h3> There is limited data on nutritional outcomes post intestinal transplantation in adults. This cohort of patients will inevitably be at high risk and undergoing major surgery anticipated to have a further deleterious effect. <h3>Methods</h3> Pre transplant anthropometric status all or multivisceral from 2007 2013 who survived more than 30 days was collected prospectively. A dynamometer used assess grip strength the non-dominant hand. Bone density measured by dual x-ray...
<h3>Aim</h3> This project aimed to evaluate the time taken for formal reporting of blood culture results, associated impact this on prescribing appropriate antibiotic therapy and defining period starvation whilst PN is withheld patients with catheter related bloodstream infections (CRBSI) <h3>Method</h3> Clinical data were retrospectively collected from electronic paper records Type 1 intestinal failure diagnosed CRBSI outside an unit at a single centre April st 2016 March 31 2017. Data...
This project aimed to evaluate the time taken for formal reporting of blood culture results, associated impact this on prescribing appropriate antibiotic therapy and defining period starvation while parenteral nutrition (PN) is withheld patients with catheter-related bloodstream
<h3>Introduction</h3> Intestinal failure associated liver disease (IFALD) refers to injury due intestinal (IF) and parenteral nutrition (PN). This presents as steatosis cholestasis which can lead fibrosis cirrhosis. ESPEN recommends that IFALD should be diagnosed by the presence of abnormal function tests (LFTs) with radiological and/or histological evidence abnormality. Non-invasive such FIB-4, ELF Fibroscan<sup>®</sup> are not validated in patients IFALD. We assessed diagnostic correlation...