A5070415173- Pancreatic and Hepatic Oncology Research
- Epigenetics and DNA Methylation
- Ovarian function and disorders
- Nanoparticle-Based Drug Delivery
- Sperm and Testicular Function
- Nigella sativa pharmacological applications
- Hormonal and reproductive studies
- Cancer Cells and Metastasis
- Cancer Research and Treatments
- Menopause: Health Impacts and Treatments
- Nanoplatforms for cancer theranostics
- Advanced biosensing and bioanalysis techniques
- Acne and Rosacea Treatments and Effects
- Reproductive Biology and Fertility
- Estrogen and related hormone effects
- Lanthanide and Transition Metal Complexes
- 14-3-3 protein interactions
- Fish Biology and Ecology Studies
- Reproductive Health and Technologies
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Pregnancy and preeclampsia studies
- Animal Diversity and Health Studies
- Plant and animal studies
- Ecology and Vegetation Dynamics Studies
University of Calcutta
2006-2024
Bose Institute
2006-2024
Zoological Survey of India
2023-2024
The University of Texas Southwestern Medical Center
2021-2023
Changshu Institute of Technology
2017-2022
Techno India University
2021
Aberdeen Maternity Hospital
2018
University of Aberdeen
2018
KPC Medical College and Hospital
2011-2017
All India Institute of Medical Sciences
2017
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual loading, efficient delivery and significantly inhibited tumor growth as well retarded metastasis in triple-negative breast cancer.
Abstract The degree of metastatic disease varies widely among patients with cancer and affects clinical outcomes. However, the biological functional differences that drive extent metastasis are poorly understood. We analyzed primary tumors paired metastases using a multifluorescent lineage-labeled mouse model pancreatic ductal adenocarcinoma (PDAC)—a tumor type in which most present metastases. Genomic transcriptomic analysis revealed an association between burden gene amplification or...
The detailed molecular mechanism of transferrin-tagged thymoquinone nanoparticle mediated apoptotic induction in non-small cell lung carcinoma showing the involvement p53 dependent synergistic activation miR-34a and miR-16 pathway.
AIM:To evaluate the protective activity of allylpyrocatechol (APC), major antioxidant constituent Piper betel , against indomethacin-induced stomach ulceration in rat model and correlates with its antioxidative mucin protecting properties. METHODS:Male Sprague-Dawley rats were divided into five groups.Normal control (group Ⅰ) given vehicle oral dose gum acacia distilled water (1 mL per rat); ulcerated treated (groups Ⅱ-Ⅴ) a single indomethacin (30 mg/kg body wt.); group Ⅱ sacrificed 4 h...
Seed germination is the key step for successful establishment, growth and further expansion of population especially alien plants with annual life cycle. Traits like better adaptability response were thought to be associated plant invasion. However, there are not enough empirical studies correlating adaptation environmental factors invasive plants. In this study, we conducted congeneric comparisons different such as light, pH, NaCl, osmotic soil burials among four amaranths that differ in...
This study develops water dispersible trivalent terbium cation incorporated zinc sulfide nanoparticles for potential anti-cancer therapy and cellular imaging.
Triple negative breast cancer (TNBC) tends to form aggressive tumors associated with high mortality and morbidity which urge the need for development of new therapeutic strategies. Recently, normal metabolite Methylglyoxal (MG) has been documented its anti‐proliferative activity against human cancer. However, mode action MG TNBC remains open question. In our study, we investigated anticancer in MDA MB 231 4T1 cell lines elucidated underlying mechanisms. dose‐dependently caused death, induced...
HepG2 cells (HCC), characterized by epithelial-like morphology, high proliferation rates, and nontumorigenicity, require cost-effective efficient treatment. Silymarin, a flavonoid extract of Silybum marianum, is effective in the treatment HCC. Here, we have reported comparative anticancer study well-characterized nanoformulations lactobionic acid-adorned porous PLGA-encapsulated silymarin (LA-PLGA-Sil) with only (PLGA-Sil) against cells. Treatment LA-PLGA-Sil produced significant...
Epidermal growth factor receptor (EGFR) normally over-expresses in non-small cell lung cancer (NSCLC) cells. Its mutations act as oncogenic drivers the cellular signal transduction pathway, and induce downstream activation of numerous key events involved proliferation survival. EGFR tyrosine kinase inhibitors (EGFR-TK inhibitors), such gefitinib erlotinib, have been used for a long time treatment NSCLC. However, they fail to overcome EGFR-TK mutation due acquisition drug resistance. It is...
Mushrooms are customary influential sources of pharmaceutically active metabolites. Usually lanostane-type triterpenoids from mushrooms had prospective for cancer disease treatments. Recently, a triterpenoid, astrakurkurol obtained the fresh basidiocarps edible mushroom Astraeus hygrometricus, drew attention as new cytotoxic therapeutic. The structural stability this triterpenoid been established with amalgamation density functional theory (DFT) calculations and study single-crystal X-ray...
Abstract Invasive alien plants threaten biodiversity across the world. Erigeron canadensis (horseweed) is one of most problematic agricultural weeds and represents a classic example intercontinental invasion. Here, we studied genetic diversity population structure invasive populations from Jiangsu Zhejiang Provinces in China native Alabama, USA. We used 10 polymorphic SSR loci to genotype 312 individuals 5 estimate structure. showed, on average, similar indicating no severe bottlenecks...
Multi drug resistance (MDR) in breast carcinoma still poses a significant impairment to successful chemotherapy. As the arsenal of anticancer agents increases with improved preclinical methods, growth therapeutic combinations is now unprecedented. The malignancies addressed by mono drugs often fail limit cancer progression, resulting resistant cancer, thereby offering combinatorial therapies terrific edge over monodrug regimes. However, selection required enough preliminary evidence for...
This work introduces APTMS capped Ti(Sm)O<sub>2</sub> nanoparticles as reporters for live-cell imaging with negligible cytotoxicity and resistance to photobleaching.
The computational capability of living systems has intrigued researchers for years. Primarily, the focus been on implementing aspects in devices. Computer literal peoples expand their hand to molecular biologist and chemist explore potential computation biological molecules line Deoxyribonucleic Acid (DNA) Ribonucleic (RNA) which are information carrying molecules. In this context, DNA is basically a collection specially selected strands whose combinations will result solution some problems....