A5100767634- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Sleep and Wakefulness Research
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Respiratory Support and Mechanisms
- Sleep and related disorders
- Cardiovascular and Diving-Related Complications
- Medical Research and Treatments
- EEG and Brain-Computer Interfaces
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Nutrition and Health in Aging
- Cardiac Imaging and Diagnostics
- Medical Imaging and Pathology Studies
- Phytochemicals and Medicinal Plants
- Gastroesophageal reflux and treatments
- Gout, Hyperuricemia, Uric Acid
- Sleep and Work-Related Fatigue
- Cardiac pacing and defibrillation studies
- Nasal Surgery and Airway Studies
- Cardiac Valve Diseases and Treatments
- Platelet Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
Beijing Tongren Hospital
2016-2025
Capital Medical University
2016-2025
Henan Provincial People's Hospital
2020-2025
Fujian Medical University
2015-2025
Second Affiliated Hospital of Fujian Medical University
2015-2025
Nanjing Agricultural University
2025
Jilin Agricultural University
2022-2024
Zhengzhou University
2024
Tianjin People's Hospital
2024
Ministry of Education of the People's Republic of China
2018-2024
The financing difficulty of green innovation projects has always been an obstacle to enterprises’ innovation. Digital financial inclusion provides a new opportunity solve the Based on construction theoretical framework for digital influence innovation, this study empirically analyzes impact and mechanism by using provincial panel data China from 2011 2020. results show that significant positive promotion effect development is mainly driven depth use digitalization inclusion. intermediary...
To validate the hypothesis that fat tissue accumulation adjacent to upper airway contributes a predisposition obstructive sleep apnea (OSA), irrespective of body mass index (BMI), as well investigate effect volume on pharyngeal mechanical loads.Fourteen subjects and 14 controls were enrolled in this study. Pharyngeal anatomy (the retropalatal region retroglossal region) evaluated using magnetic resonance imaging. Whether had segmental closing pressure higher than atmospheric was determined...
To test whether the integration of both anatomical and nonanatomical parameters (ventilatory control, arousal threshold, muscle responsiveness) in a physiology-based model will improve ability to predict outcomes after upper airway surgery for obstructive sleep apnea (OSA).In 31 patients who underwent OSA, loop gain threshold were calculated from preoperative polysomnography (PSG). Three models compared: (1) multiple regression based on an extensive list PSG alone; (2) multivariate using...
Abstract Purpose To develop an automated framework for sleep stage scoring from PSG via a deep neural network. Methods An network was proposed by using multi-model integration strategy with multiple signal channels as input. All of the data were collected one single medical center July 2017 to April 2019. Model performance evaluated overall classification accuracy, precision, recall, weighted F1 score, and Cohen’s Kappa. Results Two hundred ninety-four studies included in this study; 122...
The variability of the apnea-hypopnea index（AHI） measured in first and second halves night is significant patients with obstructive sleep apnea hypopnea syndrome（OSAHS）. This variation may be related to fluid redistribution caused by supine position during sleep.
Antimicrobial peptides (AMPs) present a promising avenue to combat the growing threat of antibiotic resistance. The ruminant gastrointestinal microbiome serves as unique ecosystem that offers untapped potential for AMP discovery.
The effect of targeted temperature management (TTM) combined with decompressive craniectomy (DC) on poor-grade aneurysmal subarachnoid hemorrhage (aSAH) has not been previously addressed in the literature. This study aims to investigate therapeutic outcomes combination TTM and DC patients aSAH. represents a secondary analysis Multicenter Clinical Research Targeted Temperature Management Poor-grade Aneurysmal Subarachnoid Hemorrhage (High-Quality for PaSAH), multicenter prospective conducted...
This study aims to evaluate the clinical utility of metagenomic next-generation sequencing (mNGS) for diagnosing central nervous system infections (CNSIs) during perioperative period in neurosurgical intensive care unit (ICU) patients. In this prospective study, we included patients suspected CNSIs who were admitted Neurosurgical-ICU at Henan Provincial People's Hospital. Clinical samples tested using both mNGS and conventional pathogen culture methods. Based on comprehensive diagnoses,...
Background This study evaluates the performance of GPT-4o in detecting errors ACR TIRADS ultrasound reports and its potential to reduce report generation time. Methods A retrospective analysis 200 thyroid from Second Affiliated Hospital Fujian Medical University was conducted, with categorized as correct or containing up three errors. GPT-4o's compared physicians varying experience levels error detection processing Results detected 90.0% (180/200) errors, slightly less than best-performing...
Antimicrobial resistance (AMR) presents a pressing global health crisis, particularly in the post-pandemic era, underscoring urgent need for innovative therapeutics. peptides (AMPs) hold promises combating multidrug-resistant infections but are hindered by challenges clinical translation, including limited hemocompatibility and inefficient design processes. To overcome these obstacles, we developed AIPAMPDS, an AI-driven computational platform that integrates deep generative model with...
Triphala is an Ayurvedic rasayana formulation reputed for its antitumour activities, and chebulinic acid chebulagic acid, along with other phenolic acids, have been proposed to be responsible effects. In this study, the anti-proliferative activities of these agents were evaluated in colorectal carcinoma cell lines three phenotypes exposed several batches triphala samples different quantities acid. The pro-apoptotic anti-migratory probable mechanisms more potent phytochemical also...
Controversy exists as to whether elevated loop gain is a cause or consequence of obstructive sleep apnea (OSA). Upper airway surgery commonly performed in Asian patients with OSA who have failed positive pressure therapy and are thought anatomical predisposition OSA. We hypothesized that high would decrease following surgical treatment due reduced severity.Polysomnography was preoperatively postoperatively assess severity 30 Chinese participants underwent upper surgery. Loop calculated using...
This paper investigates the effect of crop insurance-subsidies on agricultural land-use allocation. Since objective insurance is to help farmers with risk management, expected profit from production under might be improved, leading allocate more land production. In this paper, type classified by irrigated/unirrigated farmland and cropland/woodland/pastureland. The data come counties all continental states. Considering fractional outcome share, we apply a multinomial-fractional-logit model...
We assessed the effectiveness and safety of target temperature management (TTM) in treating patients with poor-grade aneurysmal subarachnoid hemorrhage (aSAH). The primary objective was to evaluate neurological outcome at 3 months. Secondary objectives were assess mortality, delayed cerebral ischemia, edema, hydrocephalus, midline shift, laboratory indicators related TTM.
Background Obstructive sleep apnea (OSA) is a sleeping disorder that can cause multiple complications.
To explore whether the variables resulting from anatomical and physiological examinations can be combined to predict outcomes of velopharyngeal surgery for obstructive sleep apnea (OSA).Prospective design with a retrospective review.A total 119 patients OSA received surgery, including revised uvulopalatopharyngoplasty uvula preservation transpalatal advancement pharyngoplasty. The preoperative these patients, polysomnography (PSG), physical examination, three-dimensional computer tomography...
Rationale: Obstructive sleep apnea (OSA) has multiple pathophysiological causes. A low respiratory arousal threshold (ArTh) and a high loop gain (unstable ventilatory control) can contribute to recurrent events in patients with OSA. Prior studies have shown that donepezil, an acetylcholinesterase inhibitor, might improve OSA, but the mechanism is unknown.Objectives: To determine whether single dose of donepezil lowers apnea–hypopnea index by modulating ArTh or gain.Methods: In this...