A5023013987- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Semiconductor materials and devices
- Gastric Cancer Management and Outcomes
- Thin-Film Transistor Technologies
- Silicon and Solar Cell Technologies
- Electronic and Structural Properties of Oxides
- Silicon Carbide Semiconductor Technologies
- Genetic factors in colorectal cancer
- Liver Disease Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- T-cell and B-cell Immunology
- Copper Interconnects and Reliability
- Pulmonary Hypertension Research and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Semiconductor materials and interfaces
- RNA modifications and cancer
- Sphingolipid Metabolism and Signaling
- Acoustic Wave Resonator Technologies
- Gastrointestinal Tumor Research and Treatment
- Photonic and Optical Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myeloid Leukemia Research
- Silicon Nanostructures and Photoluminescence
The First People's Hospital of Changde
2025
Jiangjin Central Hospital
2024
Weatherford College
2024
Affiliated Hospital of Guizhou Medical University
2022-2024
Guiyang Medical University
2022-2024
GTx (United States)
2001-2024
Shanghai Jiao Tong University
2024
Shanxi Medical University
2019-2023
Jiangsu Vocational College of Medicine
2020-2023
Shanxi Academy of Medical Sciences
2022-2023
Abstract Background Laryngeal squamous cell carcinoma (LSCC) is a common malignant tumor of the head and neck. LSCC patients have seriously impaired vocal, respiratory, swallowing functions with poor prognosis. Circular RNA (circRNA) has attracted great attention in cancer research. However, expression patterns roles circRNAs remain largely unknown. Methods sequencing was performed on 57 pairs matched adjacent normal mucosa tissues to construct circRNA, miRNA, mRNA profiles. RT-PCR, qPCR,...
Ischemia reperfusion injuries (IRI) are unavoidable in solid organ transplantation. IRI augments alloimmunity but the mechanisms involved poorly understood. Herein, we examined effect of on antigen specific alloimmunity. We demonstrate that ischemia promotes alloimmune activation, leading to more severe histological features rejection, and increased CD4
Depression represents a significant clinical concern for individuals diagnosed with non-small cell lung cancer (NSCLC) following surgical resection. This study aimed to investigate the potential of preoperative peripheral blood parameters, including neutrophil/lymphocyte ratio (NLR), lymphocyte/monocyte (LMR), and platelet/lymphocyte (PLR), as predictive indicators risk developing depression within initial 90-day postoperative period in NSCLC patients. A prospective cohort was conducted,...
BACKGROUND Multiple primary malignant tumors refer to the occurrence of two or more in same organ multiple organs tissues at time successively patient, and can occur anywhere body. The treatment guidelines for patients with are currently controversial. CASE SUMMARY A 51-year-old male patient liver cancer portal hypertension received 42 months co-treatment atezolizumab bevacizumab. After that, disease was rated stable disease. then diagnosed gastric cancer. Since not sensitive anti-programmed...
Hepatocellular carcinoma (HCC) is one of the most common cancers in world and particularly prevalent China. China also a hyperendemic area for hepatitis B virus (HBV) infection. Although strong association between HBV infection HCC has been established previously, role C (HCV) interaction HCV development not adequately explored. The major objective this study to determine relationship or by use case-control Henan, In all, 152 patients 115 control were collected from four hospitals January...
BACKGROUND:Coronary heart disease (CHD) is a cardiovascular characterized by high morbidity and mortality. Vascular endothelial growth factor (VEGF) its receptor, named kinase insert domain-containing receptor (KDR, or VEGFR2), which are involved with angiogenesis vascular repair, could partly contribute to the development of CHD. The aim this study, therefore, was investigate potential correlations between genetic polymorphisms on VEGF KDR susceptibility CHD, integrative role SNPs combined...
Maladaptive right ventricular (RV) remodeling is the most important pathological feature of pulmonary hypertension (PH), involving processes such as myocardial hypertrophy and fibrosis. A growing number studies have shown that mitochondria-associated endoplasmic reticulum membranes (MAMs) are involved in various physiological processes, calcium homeostasis, lipid metabolism, inflammatory response, mitochondrial dynamics, autophagy/mitophagy. The abnormal expression MAMs-related factors...
Abstract STRIP2 (FAM40B) was reported to regulate tumor cell migration. Our study aims discuss the effect of in mouse aortic smooth muscle (MOVAS) proliferation and migration processes, which contributes greatly atherosclerosis formation. In MOVAS cells, depletion suppressed migration, were related a remarkable decrease matrix metalloproteinases‐2 (MMP‐2)/MMP‐9 expression. Additionally, P38 mitogen‐activated protein kinases Protein kinase B (AKT) are inactivated while extracellular...
Abstract Fascin actin‐bundling protein 1 (FSCN1) is an evolutionarily conserved that plays a critical role in cell migration, motility, adhesion, and cellular interactions. Although multiple clinical studies have implicated the expression of FSCN1 laryngeal squamous carcinoma (LSCC) progression, precise mechanism process has not been clearly elucidated. To define function, we characterized FSCN1‐interacting proteins LSCC cells by immunoprecipitation followed mass spectrometry (MS). After...
Envafolimab is a novel inhibitor for programmed cell death protein-ligand 1 (PD-L1) that can be administered subcutaneously. It has been found to effective and safe in the treatment of advanced high microsatellite unstable (MSI-H) / mismatch repair deficient (dMMR) solid tumors. Currently, efficacy protein-1 (PD-1) inhibitors stable (MSS) tumors not clear. We report case colon cancer with MSS metastases bilateral clavicle, mediastinum, retroperitoneum, hilum, left side thoracic 11/12...
Abstract: Currently, effective therapies for advanced gastric cancer with systemic metastasis are lacking. Pharmacological research has been slowly progressing over the past decades. Here, we report case of a 56-year-old female human epidermal growth factor receptor 2 (HER2) expression (IHC 2+/FISH-) in metastasis. The first-line therapeutic regime consisted administration camrelizumab, local arterial infusion oxaliplatin and embolization, oral apatinib, PS scheme (oral...
The guidelinesthat specify whether antibiotic prophylaxis should be administered before laparoscopic clean-contaminated wound to prevent postoperative surgical site infection (SSI) need improved. Studies have shown that elective cholecystectomy with does not require prophylaxis. However, there are no studies on the effect of SSI after appendectomy for chronic appendicitis (LCA), which is a wound.We conducted single-center, double-blind, randomized controlled clinical trial. A total 106...