- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Alcoholism and Thiamine Deficiency
- Cerebral Venous Sinus Thrombosis
- Epilepsy research and treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Intensive Care Unit Cognitive Disorders
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Neurological and metabolic disorders
- Pharmacological Effects and Toxicity Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Shoulder Injury and Treatment
- Neuroscience of respiration and sleep
- Anatomy and Medical Technology
- Electrolyte and hormonal disorders
- MRI in cancer diagnosis
- Neonatal and fetal brain pathology
- Intracranial Aneurysms: Treatment and Complications
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Nursing Education, Practice, and Leadership
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Novant Health Forsyth Medical Center
2013-2023
Novant Health
2018-2021
KU Leuven
2016
University of Missouri–Kansas City
2005
Ziekenhuisnetwerk Antwerpen Stuivenberg
2000
Background and Purpose: Although most strokes present with mild symptoms, these have been poorly represented in clinical trials. The objective of this study is to describe multidimensional outcomes, identify predictors worse explore the effect thrombolysis population. Methods: This prospective observational included patients ischemic stroke or transient attack, a baseline National Institutes Health Stroke Scale (NIHSS) score 0 5, presenting within 4.5 hours from symptom onset. primary...
Maintaining carotid patency and avoiding symptomatic intracranial hemorrhage are competing concerns in tandem occlusions. This study provides data regarding the safety efficacy of eptifibatide stroke from occlusion extracranial artery or middle cerebral artery.This is a retrospective analysis 58 consecutive patients who received low-dose (135-mcg/kg bolus, 1-mcg/kg/min infusion) during treatment Brain imaging sonography were performed at 24-36 hours. mRS was documented 90 days, sonography,...
Background Emergent neuroendovascular stenting presents challenges for the utilization of antiplatelet agents. Methods This was a multicenter, retrospective cohort patients who underwent emergent stenting. The primary endpoints were thrombotic and bleeding events in relation to timing administration, route choice intravenous (IV) agent study investigated practice variability utilization. Results Five-hundred seventy screened across 12 sites. Of those, 167 included data analysis. For...
Clinical fluctuations in ischemic stroke symptoms are common, but before hospital arrival have not been previously characterized.A standardized qualitative assessment of was obtained an observational study that enrolled patients with mild (National Institutes Health Stroke Scale [NIHSS] score 0-5) present on to within 4.5 hours onset, a subset 100 hospitals participating the Get With The Guidelines-Stroke quality improvement program. number fluctuations, direction, and overall or worsening...
Background: Generalized epileptic convulsions frequently exhibit transient respiratory symptoms and non-infectious leukocytosis. While these peri-ictal effects appear to arise independently from one another, the possibility that they stem a common ictal pathophysiological response has yet be explored. We aimed investigate whether postictal leukocytosis coexist. Methods: performed single center retrospective chart review of 446 patients brought our emergency department between January 1, 2017...
Background and Purpose: Post-stroke depression is common, with an estimated prevalence of 30-35%. This study assessed the null hypothesis that PHQ-9 screening equivalent to standard care (suicide + provider assessment) in detection post-stroke depression. A secondary outcome was assess optimal timing setting perform after stroke. Methods: screenings modified Rankin Scales were conducted a prospective population (n=49) at three time points - inpatient within 48 hours admission for stroke, 7...
1Novant Health Forsyth Medical Center, Winston Salem, NC 2Novant Winston-Salem,
<h3>Background</h3> Intracranial atherosclerosis (ICAD) is much less common than embolism as a cause of emergency large vessel occlusion (ELVO) in patients presenting for endovascular therapy. The presence ICAD may be known pre-operatively or discovered during the course intervention. angioplasty and/or stenting employed to establish patency target vessel, and emergent anti-platelet medical therapy required maintain patency. latter must balanced with risk causing intracranial hemorrhage...
<h3>Background</h3> Tandem occlusion of the cervical internal carotid artery and terminus or middle cerebral represents a special, more challenging, type emergent large vessel occlusion. Unlike straightforward case cardiogenic embolism, tandem presents simultaneous problem an intracranial embolus, acute thrombotic event in artery. occlusions challenge neurointerventionalist to balance competing priorities preventing hemorrhage with establishing preserving patency The optimal medical regimen...
Background and Purpose: Thrombophilic states are an uncommon primary mechanism of ischemic stroke in adults. The role screening for inherited thrombophilia is unclear, but may be considered cryptogenic stroke. aim this study was to assess the clinical utility costs testing. A secondary characterize demographics risk factors tested individuals. Methods: Two year, two center, retrospective, observational patients with testing obtained during inpatient admission. Economic burden calculated as...
<h3>Introduction</h3> Tandem intracranial/extracranial occlusion presents a challenge due to the coincident risks of symptomatic intracranial hemorrhage (SICH) and carotid re-occlusion. Various anti-thrombotic regimens have been reported with mixed results for SICH, but infrequent analysis cervical patency. We present single center, retrospective tandem patients treated low dose eptifibatide, emphasis on rates rigorous reporting artery The work is unique completeness vessel imaging...