Christina Roels

ORCID: 0000-0002-6537-5810
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Stroke Rehabilitation and Recovery
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Alcoholism and Thiamine Deficiency
  • Cerebral Venous Sinus Thrombosis
  • Epilepsy research and treatment
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Intensive Care Unit Cognitive Disorders
  • Venous Thromboembolism Diagnosis and Management
  • Peripheral Artery Disease Management
  • Neurological and metabolic disorders
  • Pharmacological Effects and Toxicity Studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Shoulder Injury and Treatment
  • Neuroscience of respiration and sleep
  • Anatomy and Medical Technology
  • Electrolyte and hormonal disorders
  • MRI in cancer diagnosis
  • Neonatal and fetal brain pathology
  • Intracranial Aneurysms: Treatment and Complications
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Nursing Education, Practice, and Leadership

United Nations Economic and Social Commission for Asia and the Pacific
2021-2024

Novant Health Forsyth Medical Center
2013-2023

Novant Health
2018-2021

KU Leuven
2016

University of Missouri–Kansas City
2005

Ziekenhuisnetwerk Antwerpen Stuivenberg
2000

José G. Romano Hannah Gardener Iszet Campo‐Bustillo Yosef Khan Sofie Tai and 95 more Nikesha Riley Eric E. Smith Ralph L. Sacco Pooja Khatri Heather M. Alger Brian Mac Grory Deepak Gulati Navdeep Sangha Jeffrey M. Craig Karin Olds Curtis Benesch Adam G. Kelly Scott S Brehaut Amit Kansara Lee H. Schwamm Brian Mac Grory Mayumi Oka Christina Roels Cherylee W. J. Chang Jennifer L. Moran Nicholas Lanciano C. Romero David Salvatore Neel Shah Rodney Leacock A. Rochester Jerry C. Martin Vikas Grover Maheen Malik W. R. Logan Muhib Khan Arun Babu Jestin N. Carlson Gabriel Vidal Jennifer A. Lynch Kathryn Kirchoff Jennifer Rasmussen-Winkler G.E. Thompson Stephen Martino Gillian Gordon Perue Kasey Gildersleeve Timothy C. Parsons John W. Chen David Lombardi Amer Malik Amy Guzik Robert Hoesch Dorothea Altschul Miran Salgado Indrani Acosta Terry A. Neill Abhineet Chowdhary José R. Romero Refat Assad Rebecca Sugg Muhammad M. Alvi Jonathan Hartman Ankur Garg Curtis A. Given Jeffrey Hilburn Christopher Commichau Changsoo Hahm Angel Pulido Nima Ramezan‐Arab Anna Khanna Armistead Williams R. Nagaraja Reddy Bhupat Desai Laurence Ufford Keith O. Jones Stephen Martino Elizabeth H. Wise Gauhar Chaudhary Joseph Hanna Franklin A. Marden Ajay Arora Raymond Reichwein Kelly Matmati Kumiko Owada Ashish Masih Larry Shepherd Stephen T. Gancher Matthew Smith Joseph Mazzola Edward Plyler James Napier Amer Alshekhlee Tarakad S. Ramachandran David Michael Jorolemon Padalino Collin Maloney Laxmi Dhakal Truman J. Milling Harish Shownkeen Paul A. Cullis Sajjad Mueed

Background and Purpose: Although most strokes present with mild symptoms, these have been poorly represented in clinical trials. The objective of this study is to describe multidimensional outcomes, identify predictors worse explore the effect thrombolysis population. Methods: This prospective observational included patients ischemic stroke or transient attack, a baseline National Institutes Health Stroke Scale (NIHSS) score 0 5, presenting within 4.5 hours from symptom onset. primary...

10.1161/strokeaha.120.032809 article EN Stroke 2021-05-05

Maintaining carotid patency and avoiding symptomatic intracranial hemorrhage are competing concerns in tandem occlusions. This study provides data regarding the safety efficacy of eptifibatide stroke from occlusion extracranial artery or middle cerebral artery.This is a retrospective analysis 58 consecutive patients who received low-dose (135-mcg/kg bolus, 1-mcg/kg/min infusion) during treatment Brain imaging sonography were performed at 24-36 hours. mRS was documented 90 days, sonography,...

10.3174/ajnr.a6985 article EN cc-by American Journal of Neuroradiology 2021-02-04

Background Emergent neuroendovascular stenting presents challenges for the utilization of antiplatelet agents. Methods This was a multicenter, retrospective cohort patients who underwent emergent stenting. The primary endpoints were thrombotic and bleeding events in relation to timing administration, route choice intravenous (IV) agent study investigated practice variability utilization. Results Five-hundred seventy screened across 12 sites. Of those, 167 included data analysis. For...

10.1177/15910199231180003 article EN Interventional Neuroradiology 2023-07-04
José G. Romano Hannah Gardener Eric E. Smith Iszet Campo‐Bustillo Yosef Khan and 95 more Sofie Tai Nikesha Riley Ralph L. Sacco Pooja Khatri Heather M. Alger Brian Mac Grory Deepak Gulati Navdeep Sangha Karin Olds Curtis Benesch Adam G. Kelly Scott S Brehaut Amit Kansara Lee H. Schwamm Scott Moody Weiping Ye Vena Sobhawongse Jeffrey M. Craig Heloisa Pearson Deborah Summers Christine Boerman Christy Rice Robin Kintner Mayumi Oka Sarah Baran Christina Roels Maureen Dosunmu Cherylee W. J. Chang Jennifer L. Moran Denise Ditrich Nicholas Lanciano Aimee Mann C. Romero B L Thiele David Salvatore Annette Kujawski Taylor Neel Shah Rodney Leacock A. Rochester Fanny Guillerminet Jerry C. Martin Johnny Jones Nicol Brandon Vikas Grover Maryika Gibson Maheen Malik C. Crawford Mechem W. R. Logan Camilla Cook Muhib Khan Christa Rood Arun Babu Leah Steinig Jestin N. Carlson Mélanie Henderson Gabriel Vidal Bethany Jennings Jennifer A. Lynch Jessica Ratcliff Kathryn Kirchoff Khadean Moncrieffe Jennifer Rasmussen-Winkler Leigh Allen G.E. Thompson Christopher Firek Stephen Martino Baher Georgy Gillian Gordon Perue Nina Vekima Kasey Gildersleeve Marian Skewes Christina Valdovinos Timothy C. Parsons Cynthia Marques John W. Chen David Lombardi Brenda Perez Amer Malik Kathy Hesse Amy Guzik Sandra E. Norona Robert Hoesch Jacki Anderson Dorothea Altschul Farah Fermin Miran Salgado Jonathan Muller Indrani Acosta Brooke Hartwell Terry A. Neill Carrie Hundley Abhineet Chowdhary Tina Fortney José R. Romero Brandon Finn

Clinical fluctuations in ischemic stroke symptoms are common, but before hospital arrival have not been previously characterized.A standardized qualitative assessment of was obtained an observational study that enrolled patients with mild (National Institutes Health Stroke Scale [NIHSS] score 0-5) present on to within 4.5 hours onset, a subset 100 hospitals participating the Get With The Guidelines-Stroke quality improvement program. number fluctuations, direction, and overall or worsening...

10.1161/strokeaha.121.034124 article EN Stroke 2021-10-14

Background: Generalized epileptic convulsions frequently exhibit transient respiratory symptoms and non-infectious leukocytosis. While these peri-ictal effects appear to arise independently from one another, the possibility that they stem a common ictal pathophysiological response has yet be explored. We aimed investigate whether postictal leukocytosis coexist. Methods: performed single center retrospective chart review of 446 patients brought our emergency department between January 1, 2017...

10.3389/fneur.2019.01291 article EN cc-by Frontiers in Neurology 2019-12-06

Background and Purpose: Post-stroke depression is common, with an estimated prevalence of 30-35%. This study assessed the null hypothesis that PHQ-9 screening equivalent to standard care (suicide + provider assessment) in detection post-stroke depression. A secondary outcome was assess optimal timing setting perform after stroke. Methods: screenings modified Rankin Scales were conducted a prospective population (n=49) at three time points - inpatient within 48 hours admission for stroke, 7...

10.1161/str.45.suppl_1.wp316 article EN Stroke 2014-02-01

1Novant Health Forsyth Medical Center, Winston Salem, NC 2Novant Winston-Salem,

10.1097/01.ccm.0000458061.92707.7c article EN Critical Care Medicine 2014-11-18

<h3>Background</h3> Intracranial atherosclerosis (ICAD) is much less common than embolism as a cause of emergency large vessel occlusion (ELVO) in patients presenting for endovascular therapy. The presence ICAD may be known pre-operatively or discovered during the course intervention. angioplasty and/or stenting employed to establish patency target vessel, and emergent anti-platelet medical therapy required maintain patency. latter must balanced with risk causing intracranial hemorrhage...

10.1136/neurintsurg-2017-snis.94 article EN 2017-07-01

<h3>Background</h3> Tandem occlusion of the cervical internal carotid artery and terminus or middle cerebral represents a special, more challenging, type emergent large vessel occlusion. Unlike straightforward case cardiogenic embolism, tandem presents simultaneous problem an intracranial embolus, acute thrombotic event in artery. occlusions challenge neurointerventionalist to balance competing priorities preventing hemorrhage with establishing preserving patency The optimal medical regimen...

10.1136/neurintsurg-2017-snis.93 article EN 2017-07-01

Background and Purpose: Thrombophilic states are an uncommon primary mechanism of ischemic stroke in adults. The role screening for inherited thrombophilia is unclear, but may be considered cryptogenic stroke. aim this study was to assess the clinical utility costs testing. A secondary characterize demographics risk factors tested individuals. Methods: Two year, two center, retrospective, observational patients with testing obtained during inpatient admission. Economic burden calculated as...

10.1161/str.49.suppl_1.tp215 article EN Stroke 2018-01-22

<h3>Introduction</h3> Tandem intracranial/extracranial occlusion presents a challenge due to the coincident risks of symptomatic intracranial hemorrhage (SICH) and carotid re-occlusion. Various anti-thrombotic regimens have been reported with mixed results for SICH, but infrequent analysis cervical patency. We present single center, retrospective tandem patients treated low dose eptifibatide, emphasis on rates rigorous reporting artery The work is unique completeness vessel imaging...

10.1136/neurintsurg-2020-snis.134 article EN 2020-08-01
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