A5081955813- Air Quality and Health Impacts
- Environmental Justice and Health Disparities
- Climate Change and Health Impacts
- Birth, Development, and Health
- Health disparities and outcomes
- Health, Environment, Cognitive Aging
- Conservation, Biodiversity, and Resource Management
- Noise Effects and Management
- Obesity, Physical Activity, Diet
- Global Health Care Issues
- Statistical Methods and Bayesian Inference
- Epigenetics and DNA Methylation
- Pregnancy and preeclampsia studies
- Statistical Methods and Inference
- Advanced Causal Inference Techniques
- Gestational Diabetes Research and Management
- Diabetes and associated disorders
- Advanced Statistical Methods and Models
- Gene expression and cancer classification
- Land Rights and Reforms
- Indoor Air Quality and Microbial Exposure
- Urban Green Space and Health
- Spectroscopy and Chemometric Analyses
- Energy and Environment Impacts
- Ectopic Pregnancy Diagnosis and Management
Imperial College London
2016-2024
The Alan Turing Institute
2022-2024
Turing Institute
2022-2024
MRC Centre for Environment and Health
2016-2022
Medical Research Council
2021
National Institute for Health Research
2020
MRC Unit for Lifelong Health and Ageing
2018
University of Bologna
2008-2017
Agenzia Regionale Prevenzione e Ambiente della Regione Emilia-Romagna
2011-2015
The widely recommended procedure of Bayesian model averaging is flawed in the M-open setting which true data-generating process not one candidate models being fit. We take idea stacking from point estimation literature and generalize to combination predictive distributions, extending utility function any proper scoring rule, using Pareto smoothed importance sampling efficiently compute required leave-one-out posterior distributions regularization get more stability. compare several...
Rights-holders, practitioners, and researchers recognize the importance of Indigenous-led resource management for building a more ecologically just world addressing climate change biodiversity loss. Yet, it remains unclear how to support them in way that increases their spatial extent ensuring impact on equitable conservation. We address this gap by using Diffusion Innovations theory explain rapid spread an network Locally Managed Marine Areas Fiji. found 74.9 percent adopters had previous...
This Personal View is intended for early-career researchers who are not yet experts in statistics. The focuses on common but usually avoidable flaws the context of observational studies. I point out how study design, data collection, and statistical methods impact results research conclusions. With particular attention to planning, sample selection, biases, lack transparency misinterpretations.
Birth weight is a strong predictor of infant mortality, morbidity and later disease risk. Previous work from the 1980s indicated shift in UK towards heavier births; this descriptive analysis looks at more recent trends.Office for National Statistics (ONS) registration data on 17.2 million live, single births 1986 to 2012 were investigated temporal trends mean birth weight, potential years change changes proportions very low (<1500 g), (<2500 g) high (≥4000 weight. Analysis used multiple...
OPINION article Front. Public Health, 09 February 2021 | https://doi.org/10.3389/fpubh.2021.638767
The few studies that have investigated the relationship between emissions from municipal solid-waste incinerators and adverse pregnancy outcomes had conflicting results. We conducted a study to assess effects of air eight currently in operation Emilia-Romagna Region Italy on reproductive (sex ratio, multiple births, preterm small for gestational age [SGA] births).We considered all births (n = 21,517) women residing within 4-km radius an incinerator at time delivery during period 2003-2010...
Recent evidence highlights the epidemiological value of blood DNA methylation (DNAm) as surrogate biomarker for exposure to risk factors non-communicable diseases (NCD). DNAm exposures predicts and longevity better than self-reported or measured in many cases. Consequently, disease prediction models based on surrogates may outperform current state-of-the-art models. This study aims develop novel cardiovascular (CVD) a composite predictive CVD risk. We compared performance our newly developed...
Objective Prospective assignment at 11 + 0 to 13 6 weeks of risk for late pre‐eclampsia (PE) using eight logistic regression‐based statistical models. Methods Five hundred and fifty‐four pregnancies. Uterine artery pulsatility index, parity, body mass mean arterial pressure, pregnancy‐associated plasma protein‐A, free β‐human chorionic gonadotrophin maternal age, were combined obtain ‘ a posteriori PE’. Results We observed 39 cases (7%) PE. There 12 severe PE 27 mild According the models...
Aging | doi:10.18632/aging.203872. Anna Freni-Sterrantino, Giovanni Fiorito, Angelo D'Errico, Oliver Robinson, Marianna Virtanen, Leena Ala-Mursula, Marjo-Riitta Järvelin, Justiina Ronkainen, Paolo Vineis
Some studies have reported associations between municipal waste incinerator (MWI) exposures and adverse birth outcomes but there are few of modern MWIs operating to current European Union (EU) Industrial Emissions Directive standards. Associations modelled ground-level particulate matter ≤10 μm in diameter (PM10) from MWI emissions (as a proxy for emissions) within 10 km each MWI, selected infant mortality were examined all 22 Great Britain 2003–10. We also investigated with proximity...
Municipal Waste Incineration (MWI) is regulated through the European Union Directive on Industrial Emissions (IED), but there ongoing public concern regarding potential hazards to health. Using dispersion modeling, we estimated spatial variability in PM10 concentrations arising from MWIs at postcodes (average 12 households) within 10 km of Great Britain (GB) 2003–2010. We also investigated change points emissions relation introduction EU (EU-WID) (subsequently transposed into IED) and...
Abstract Aims/hypothesis Type 1 diabetes is an autoimmune disease affecting ~400,000 people across the UK. It likely that environmental factors trigger process in genetically susceptible individuals. We assessed associations between a wide range of and childhood type incidence England, using agnostic, ecological environment-wide association study (EnWAS) approach, to generate hypotheses about triggers. Methods undertook analyses at local authority district (LAD) level national hospital...
Unintentional non-fire related (UNFR) carbon monoxide (CO) poisoning is a preventable cause of morbidity and mortality. Epidemiological data on UNFR CO can help monitor changes in the magnitude this burden, particularly through comparisons multiple countries, to identify vulnerable sub-groups population which may be more at risk. Here, we collected age- sex- specific number hospital admissions with primary diagnosis England (2002-2016), aggregated small areas, alongside area-level...
1. Forest restoration has the potential to contribute climate, biodiversity, and human well-being, responding multiple global sustainable development goals. Yet, little is known about factors associated with local actors’ choice engage in forest restoration, limiting of effective scaling strategies. 2. Our study examines spatial socio-ecological landowners’ engagement documented by Atlantic Restoration Pact Brazil. To meet this aim, we draw on Diffusion Innovations theory model associations...
To investigate long-term associations between metal components of particulate matter (PM) and mortality lung cancer incidence.Small area (ecological) study.Population living in all wards (~9000 individuals per ward) the London Oxford England, comprising 13.6 million individuals.We used land use regression models originally Transport related Air Pollution Health Impacts-Integrated Methodologies for Assessing Particulate Matter study to estimate exposure copper, iron zinc ambient air PM. We...
Occupation-related stress and work characteristics are possible determinants of social inequalities in epigenetic aging but have been little investigated. Here, we investigate the association several with age acceleration (AA) biomarkers. The study population included employed unemployed men women (n = 631) from UK Understanding Society study. We evaluated employment related to job type, stability; schedule; autonomy influence at work; occupational physical activity; feelings regarding four...
There is limited evidence on potential health risks from Municipal Waste Incinerators (MWIs), and previous studies birth outcomes show inconsistent results. Here, we evaluate whether the opening of MWIs associated with infant mortality sex ratio in surrounding areas, extending Interrupted Time Series (ITS) methodological approach to account for spatial dependencies at small area level.We specified a Bayesian hierarchical model investigate annual sex-ratio (female relative male) within 10 km...
Bioaerosols have been associated with adverse respiratory-related health effects and are emitted in elevated concentrations from composting facilities. We used modelled Aspergillus fumigatus concentrations, a good indicator for bioaerosol emissions, to assess associations hospital admissions. Mean daily were estimated each site first full year of permit issue 2005 onwards 2014 Census Output Areas (COAs) within 4 km 76 facilities England, as previously described (Williams et al., 2019)....
Background: There is an increasing body of evidence associating short-term ambient nitrogen dioxide (NO 2 ) exposure with asthmarelated hospital admissions in children.However, most studies have relied on temporally resolved information, potentially ignoring the spatial variability NO .We aimed to investigate how daily estimates from a highly spatio-temporal model are associated risk emergency admission for asthma children England.Methods: We conducted time-stratified case-crossover study...
Abstract Forest restoration can potentially contribute to multiple global sustainable development goals. Yet, little is known about the factors associated with local actors' choice engage in restoration, limiting of effective scaling strategies. Our study examines spatial socio‐ecological landowners' engagement forest documented by Atlantic Restoration Pact Brazil. We draw on Diffusion Innovations theory model associations between and explanatory variables among 222,000 private properties...