A5082339147- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive System and Pregnancy
- Birth, Development, and Health
- Ectopic Pregnancy Diagnosis and Management
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Gestational Diabetes Research and Management
- COVID-19 Impact on Reproduction
- Pregnancy and Medication Impact
- Renal and related cancers
- Neonatal and fetal brain pathology
- Vascular anomalies and interventions
- Microscopic Colitis
- Congenital Heart Disease Studies
- Central Venous Catheters and Hemodialysis
- Pregnancy-related medical research
- Systemic Lupus Erythematosus Research
- Hip and Femur Fractures
- Congenital heart defects research
- Gestational Trophoblastic Disease Studies
- Bone and Joint Diseases
Magna Graecia University
2025
Anna University, Chennai
2025
University of Ferrara
2010-2024
Arcispedale Sant'Anna
2017-2024
Ospedale Sant'Anna
2019-2024
IRCCS Policlinico San Donato
2022-2023
Istituto Superiore di Sanità
2023
University of Bologna
2006-2011
Abstract Objectives To evaluate the strength of association between maternal and pregnancy characteristics risk adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis a multinational, cohort study on all consecutive pregnant women laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 73 centers 22 different countries. A case was defined as positive result real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay...
To investigate pregnancy outcomes in women with autoimmune rheumatic diseases (ARD) the Italian prospective cohort study P-RHEUM.it.
Abstract Background Gastrointestinal Infections (GIs) pose a significant challenge in patients with inflammatory bowel diseases (IBD), complicating its management and triggering IBD relapses. The overlap clinical symptoms makes complex differentiating GIs from flares, impacting therapeutic decisions. This study aims at evaluating the long-term impact of patients. Methods From January 2020 to September 2024, 102 (mean age 45±16 yrs; 78 ulcerative colitis, UC 24 Crohn’s disease, CD)...
Objective To determine the performance of screening for late pre‐eclampsia (PE) by maternal characteristics, uterine artery Doppler and a set biochemical markers at 11 + 0 to 13 6 weeks' gestation. Methods Prospectively enrolled women weeks. Maternal highest UtA pulsatility index serum placental biomarkers including pregnancy‐associated plasma protein‐A, growth factor, soluble fms‐like tyrosine kinase 1, P‐selectin neutrophil gelatinase‐associated lipocalin were recorded. Results The rate PE...
Objective Prospective assignment at 11 + 0 to 13 6 weeks of risk for late pre‐eclampsia (PE) using eight logistic regression‐based statistical models. Methods Five hundred and fifty‐four pregnancies. Uterine artery pulsatility index, parity, body mass mean arterial pressure, pregnancy‐associated plasma protein‐A, free β‐human chorionic gonadotrophin maternal age, were combined obtain ‘ a posteriori PE’. Results We observed 39 cases (7%) PE. There 12 severe PE 27 mild According the models...
Objective The aim of this study was to evaluate whether the quantitative distribution a panel circulating mRNAs from maternal whole blood normal pregnancies is statistically different those complicated with preeclampsia (PE) or without intrauterine growth restriction (IUGR). Methods Maternal six subjects mild severe PE IUGR and 30 matched controls (1:5 match for gestational age) were retrospectively examined mRNA markers. Seven specific markers identified chosen based on previous microarray...
Abstract Objectives To determine the gene expression profile in chorionic villous samples (CVS) of women destined to develop preeclampsia. Method cDNA microarray technology was employed. Ten singleton fetuses who subsequently developed preeclampsia where compared with a pool 50 controls. The mRNA some genes previously found be up‐ or down‐regulated were validated by RT‐PCR peripheral blood from 23 pregnant at term affected and Results Altered among several including those involved invasion...
To compare, using a unified approach, standardized estimated fetal weight (EFW) trajectories from the second trimester to birth and birth-weight (BW) measurements in in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) pregnancies obtained after frozen-thawed vs fresh blastocyst transfer (BT).This was secondary analysis of prospective longitudinal cohort study performed at Fetal Medicine Obstetric Departments San Raffaele Hospital Milan, Italy, January 2016 December 2020....
Abstract Objectives To determine the gene expression profile in chorionic villous samples (CVSs) of women destined to develop pre‐eclampsia (PE). Method Case‐control study encompassing five PE [cases matched for gestational age with 30 controls]. We quantified mRNA on tissue from CVS normal and patients. then assessed expressions cathepsin (CTSD), angiopoietin 2 (ANGPT2), interleukin 8, chemokine (C‐X‐C motif) ligand 10, neurokinin B (NKB), matrix metallopeptidase 9, major histocompatibility...
Abstract STUDY QUESTION Do uterine arteries Doppler studies show different pulsatility index (UtA-PI) measurements in IVF/ICSI pregnancies with oocyte donation (OD) as compared to natural conceptions? SUMMARY ANSWER In OD, UtA-PI is reduced by an average of about 40% conception. WHAT IS KNOWN ALREADY OD present worse pregnancy outcomes conception, particularly for increased incidence pre-eclampsia (PE). Recent evidence shows that frozen blastocyst transfer also higher prevalence PE and 15%...
Cyclic adenosine 3′-5′-monophosphate (cAMP) is a second messenger, which exerts an important role in the control of human first-trimester trophoblast functions. In present study we demonstrate existence mechanism that able to extrude cAMP from trophoblast-derived cell lines, and show evidence indicating involvement multidrug resistance protein (MRP) 1, transporter belonging ATP-binding cassette family, egress. MRP1 expressed lines efflux highly reduced by inhibitor, MK-571. addition,...
•The use of ICIs is associated with an increased risk developing different forms colitis.•The 12-month clinical outcome ICI-induced colitis and the factors lack remission are poorly known.•A Crohn's disease-like pattern was a worse rate.•Having histopathological signs microscopic better rate. BackgroundData regarding patients immune checkpoint inhibitor (ICI)-induced scant. We aimed to describe colitis.Materials methodsThis retrospective, European, multicentre study....