- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Automotive and Human Injury Biomechanics
- Fiscal Policy and Economic Growth
- Transportation Safety and Impact Analysis
- Venous Thromboembolism Diagnosis and Management
- Spinal Fractures and Fixation Techniques
- Diabetic Foot Ulcer Assessment and Management
- Neuroscience and Neuropharmacology Research
- Cerebrovascular and Carotid Artery Diseases
- Adenosine and Purinergic Signaling
- Long-Term Effects of COVID-19
- Blood Pressure and Hypertension Studies
- Forensic Anthropology and Bioarchaeology Studies
- S100 Proteins and Annexins
- Medical Imaging and Analysis
- Regional Development and Environment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Syncope and Autonomic Disorders
- Healthcare Systems and Practices
- Education and Work Dynamics
- Neurological Disease Mechanisms and Treatments
- Sirtuins and Resveratrol in Medicine
- China's Socioeconomic Reforms and Governance
- COVID-19 and healthcare impacts
Fudan University
2019-2023
The First Affiliated Hospital, Sun Yat-sen University
2023
Zhongshan Hospital
2023
Sun Yat-sen University
2023
Wannan Medical College
2019-2022
Minhang District Central Hospital
2019-2022
Dynamic Research (United States)
2020
Allen Institute for Brain Science
2013
Icahn School of Medicine at Mount Sinai
2013
Shanghai University of Finance and Economics
2005-2011
Sirtuins (SIRTs), class III histone deacetylases, are well characterized for their control of cellular physiology in peripheral tissues, but influence brain under normal and pathological conditions remains poorly understood. Here, we establish an essential role SIRT1 SIRT2 regulating behavioral responses to cocaine morphine through actions the nucleus accumbens (NAc), a key reward region. We show that chronic administration increases expression mouse NAc, while induces alone, with no...
This project implemented the Stroke 1-2-0 stroke awareness programme across China and investigated its impact over a 2-year period. We initiated educational campaign special task forces (STF) nation. Massive media coverage, community-based sessions with videos other related materials induction of STF were major means promotion. delivered survey at end 2016 2018 to evaluate our effort. A total 3066 participants responded first in 2016, 15 207 China. The acceptance rate for versus FAST (an...
本文利用1995年、2002年和2007年的数据, 分析了城镇工资的性别差距的演变特 点和影响因素。研究结果表明, 1995—2007年特别是2002—2007年期间工资的性别差 距显著扩大, 其中不可解释部分的比例也越来越大, 显示了性别歧视的严重化问题。 年纪轻、学历低、职业差、行业差的女性职工在劳动力市场中受到更为严重的歧视, 导致了低收入群体性别工资差距的迅速扩大。 关键词: 城镇 性别歧视 工资差距 Using data from the 1995, 2002 and 2007 surveys, paper attempts to investigate whether gender wage gap has continued widen during period under study. To answer question, this utilizes decomposition methodology decompose difference between male female employees into explained unexplained...
A shock absorber based on the progressive failure of a composite tube was developed. The is subjected to axial compression from pressing cap at one end and folds inward other under effect crush without debris overflow. crushed compacted into hollow increases resisting force once it reaches cap. For larger strokes load increase, hole made in for composite. Three caps with different curvatures inward-folding surface two tubes were evaluated through static dynamic tests. lowered initial peak...
Abstract Background Stroke 1‐2‐0 and FAST (Face, Arm, Speech, Time) are two popular stroke educational tools that have been used in many promotion campaigns. However, few researchers investigated awareness of these among older adults communities. Methods This study was a cross‐sectional survey community‐living adults. Two family physicians conducted face‐to‐face interviews with living Minhang district, Shanghai, between October 1, 2020 November 31, 2020. The comprised three parts: basic...
Background and purposes To investigate the impact of novel coronavirus disease 2019 (Covid-19) on behavior seeking medical attention for community residents with suspected transient ischemic attack (TIA) during pandemic. Methods This was a community-based cross-sectional study living in two communities located suburb Shanghai. A face-to-face interview prospectively conducted from 20 May 2020 to 30 June between physicians residents. Suspected TIA that happened pandemic identified by symptoms...
Background: This study aimed to investigate the disparities in stroke knowledge between older adults and oldest old. Methods: Family physicians conducted a cross-sectional survey through face-to-face interviews with old of two suburban communities Minhang district, Shanghai October 1, 2020, November 30, 2020. All participants were classified as (age ≥80 years) 60–79 years). Between-group differences investigated by multivariate logistic regression analysis. Results: Overall, 466 including...
Background. Previous studies indicated that intensive blood pressure (BP) control (systolic BP < 120 mm·Hg) compared with standard (<140 was associated an increased risk of type 2 diabetes (T2D) and impaired fasting glucose (IFG) among hypertensive patients normoglycemia. However, the impact on incidence T2D for those IFG is still unknown. Methods. This a secondary analysis SPRINT (Systolic Blood Pressure Intervention Trial) study. We included participants at randomization, which...
AbstractThe number of the collision accidents between Unmanned Aerial Vehicle (UAV) and people on ground increase in recent years. It is necessary to clarify human injury characteristics brought by impact UAV promote its management. This study focuses head neck risk resulted from with a relatively large mass, difference small mass. First, model Y3-dummy (Hybrid III 50th) developed. Second, simulations are conducted analyse Y3's under different velocities, angles, locations. With increasing...
Drop test of the mine protected seat is process simulating explosion shock waveform by drop platform. And it plays an important role in stage development, design optimization, stereotype and mass production. So, simulated method for proposed this article to detonation wave, identification designing debugging generator elastic material established here. In article, principle modeling are given based on specific process, correction actual data. The methods used multiple tests. At last,...
Abstract Background To develop and validate a novel integer-based score to predict the unfavorable outcome at 3-month after ischemic stroke using dataset from Chinese population. Methods We retrospectively included 394 patients presented our center within 24 hours symptom onset. 70% of them were randomly selected as model derivation remaining 30% validation dataset. Step-wise logistic regression applied identify strong predictors outcome, which was defined modified Rankin Scale (mRS) >2....
Background and Purposes: Through this study, we hope to gain more insights into the differences in outcome following an ischemic stroke between floating population indigenous of Shanghai. Method: In retrospective cohort analyzed patients with first-ever acute who were admitted a comprehensive center Minhang district, Shanghai, from January 1, 2019, December 31, 2020. All patient's demographic data medical histories prospectively collected they followed up for at least 3 months. The...