Ryo Hasegawa

ORCID: 0000-0002-6732-3379
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Dental Health and Care Utilization
  • Tactile and Sensory Interactions
  • Molecular Biology Techniques and Applications
  • Dental Radiography and Imaging
  • COVID-19 and healthcare impacts
  • Advancements in Transdermal Drug Delivery
  • Cardiac Valve Diseases and Treatments
  • Bacterial Identification and Susceptibility Testing
  • Forensic and Genetic Research
  • Ureteral procedures and complications
  • Genetic Associations and Epidemiology
  • Infective Endocarditis Diagnosis and Management
  • Cardiac tumors and thrombi
  • Probiotics and Fermented Foods
  • Sarcoma Diagnosis and Treatment
  • Toxin Mechanisms and Immunotoxins
  • COVID-19 Clinical Research Studies
  • Pericarditis and Cardiac Tamponade
  • Advanced Drug Delivery Systems
  • HIV/AIDS oral health manifestations
  • Streptococcal Infections and Treatments
  • Otitis Media and Relapsing Polychondritis
  • Testicular diseases and treatments
  • Sarcoidosis and Beryllium Toxicity Research

Cardiovascular Institute Hospital
2025

Akita University
2023

St. Luke's International Hospital
2021-2023

Akita University Hospital
2023

Sapporo Medical University
2020

Tsurumi University
2020

Thermo Fisher Scientific (United States)
2017-2019

Akita Red Cross Hospital
2018

University of Electro-Communications
2015-2016

Saitama Municipal Hospital
2014

Background: In this international multicenter study, we aimed to determine the independent risk factors associated with increased 30 day mortality and impact of cancer novel treatment modalities in a large group patients without COVID-19 from multiple countries. Methods: We retrospectively collected de-identified data on cohort diagnosed between January November 2020 16 centers. Results: analyzed 3966 confirmed patients, 1115 2851 patients. Patients were more likely be pancytopenic have...

10.7554/elife.81127 article EN cc-by eLife 2023-01-30

Abstract Background Atrial fibrillation (AF) is associated with substantial mortality and morbidity, even when it asymptomatic and/or remains undetected. Clinical predictive models such as Charge-AF are not robust enough to be used in the clinical practice. We investigated benefits of adding echocardiographic risk variables model for its potential use targeted screening AF. Methods This study included 1108 consecutive patients aged 60±14 years old without a previous diagnosis AF referred...

10.1093/ehjci/jeae333.443 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

There are no national data available of the oral health in Myanmar. In this study, we examined dental caries status 187 school children located suburban area Naypyidaw, capital Myanmar, at age five and six analyzed by individual level tooth level. Maxillary D B were sensitive for almost same They less than maxillary A. Mandibular A tolerant caries. Prevalence Myanmar was still high. By applying item response theory multilevel modeling, analysis can be implemented to confirm tendency...

10.1155/2019/5948379 article EN cc-by International Journal of Dentistry 2019-04-28

Background: This study tested the hypothesis that dissolving microneedles are a useful transdermal drug delivery system (TDDS) for insulin. Methods: Insulin was loaded on patch (1.0 cm2) had 100 with chondroitin sulfate by microfabrication technology. Pharmacodynamic evaluation performed applying two or four patches to shaved abdominal skin of dogs, and blood samples were collected 360 min measure plasma glucose insulin levels. In diffusion experiment, containing fluorescein...

10.1089/dia.2009.0176 article EN Diabetes Technology & Therapeutics 2010-05-17

Erythropoietin (EPO) was successfully loaded on self-dissolving micropile array (SDMA) chip using chondroitin sulfate as the base polymer. "Drug glue" prepared by adding EPO solution to and SDMA formed micromolding fabrication technology. One chip, 1.0×1.0 cm, contained 100 arrays. Two types of SDMA, partially-loaded (p-SDMA) fully-loaded (f-SDMA), were prepared. The mean lengths SDMAs 474.8±8.1 μm for p-SDMA 473.4±5.2 f-SDMA. diameters basements 288.4±4.5 294.6±3.2 (f-SDMA). content...

10.1248/bpb.33.683 article EN Biological and Pharmaceutical Bulletin 2010-01-01

In developing countries, the prevalence of dental caries in children remains high, which means that implementing a simple and convenient classification is critical. The needs to be evidence-based reflect tooth-level information. this study, primary dentition 352 Myanmar school at ages 5, 6, 7 was analyzed tooth level clarify underlying data structure patterns population. Ninety-three percent subjects had mean number decayed teeth 7.54 ± 4.82. Based on item response theory analysis,...

10.3390/ijerph17207613 article EN International Journal of Environmental Research and Public Health 2020-10-19

Several studies have shown that the oral microbiome is related to systemic health, and a co-relation with several specific diseases has been suggested. The depends on environmental- community-level factors. In this observational study, microbiomes of children isolated mountain people were analyzed respect core etiology dental caries. We collected samples supragingival plaque from (age 9-13) living in Chin state Myanmar. After DNA extraction purification, next-generation sequencing V3-V4...

10.3390/ijerph17114033 article EN International Journal of Environmental Research and Public Health 2020-06-05

Metastatic spermatic cord (SC) tumor is extremely rare. Recently, we experienced a case of late-onset metastatic SC from cecal cancer. This 68-year-old man presenting with painless right mass. He had undergone hemicolectomy for cancer 6 years ago. Radical orchiectomy and adjuvant chemotherapy S-1 were performed. No recurrence was found after one year follow-up. We identified total 25 cases, including our case, on literature search via PubMed January 2000 to April 2015. The most frequent...

10.1155/2015/747261 article EN cc-by Case Reports in Urology 2015-01-01

Acute subdural hematoma (ASDH) is generally managed by large craniotomy with extended operating time and high relative blood loss. Recently, minimally invasive endoscopic evacuation of ASDH has been successfully demonstrated; however, non-elderly patients, moderate or massive cerebral contusion, enlarging are not accepted as indications for surgery. We report our experience two patients impending herniation evacuated via an surgery following emergent burr hole craniostomy. Case 1: A...

10.1016/j.inat.2018.01.005 article EN cc-by-nc-nd Interdisciplinary Neurosurgery 2018-02-03

<b><i>Introduction:</i></b> Aberrant methylation levels in the cytosine-phosphate-guanine island (CpGi) region from exon 1 to intron of zygote arrest <i>(ZAR1)</i> gene have been reported several types human cancers, including melanoma, brain tumor, and hepatocellular carcinoma. In present study, at CpGi <i>ZAR1</i> 1/intron bladder cancer specimens were analyzed using mass spectrometry. <b><i>Materials Methods:</i></b>...

10.1159/000365197 article EN Urologia Internationalis 2014-09-06

Summary Objective This study examines the reasons why Vietnamese do not avail or subscribe to Social Health Insurance (SHI). Methods collected data from Project of Development and Strengthening Management Provider Payment Basic Service Package Reimbursed by Fund in Vietnam implemented Japan International Cooperation Agency. In‐depth interviews nonsubscribers logistic regression analysis were conducted identify factors that influence enrolment Vietnam's SHI. Results The results showed...

10.1002/hpm.2941 article EN The International Journal of Health Planning and Management 2019-11-05

BACKGROUND:Fermented foods, such as yogurt, are often considered healthy; however, there have been numerous reported cases of bacteremia associated with their consumption. In this report, we present a case Bacillus subtilis var. natto (B. natto) related to the consumption natto, traditional Japanese food made from fermented soybeans. We also conducted literature review on B. bacteremia. CASE REPORT:We report 41-year-old woman who presented fever, had medical history congenital liver...

10.12659/ajcr.942553 article EN American Journal of Case Reports 2023-12-30

In this international multicenter study we aimed to determine the independent risk factors associated with increased 30-day mortality and impact of novel treatment modalities in a large group cancer non-cancer patients COVID-19 from multiple countries.We retrospectively collected de-identified data on cohort diagnosed between January November 2020, 16 centers.We analyzed 3966 confirmed patients, 1115 2851 patients. Cancer were more likely be pancytopenic, have smoking history, pulmonary...

10.1101/2022.08.25.22279181 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-08-26
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