- Advanced machining processes and optimization
- Advanced Surface Polishing Techniques
- Advanced Numerical Analysis Techniques
- Iterative Learning Control Systems
- Manufacturing Process and Optimization
- Tribology and Lubrication Engineering
- Advanced Measurement and Metrology Techniques
- Protein Structure and Dynamics
- Protein Kinase Regulation and GTPase Signaling
- Water Quality Monitoring and Analysis
- Advanced oxidation water treatment
- Adhesion, Friction, and Surface Interactions
- Receptor Mechanisms and Signaling
- Sports Dynamics and Biomechanics
- Photosynthetic Processes and Mechanisms
- Plant nutrient uptake and metabolism
- Advanced Machining and Optimization Techniques
- Metal and Thin Film Mechanics
- Enzyme Structure and Function
- Metallurgy and Material Forming
- Mass Spectrometry Techniques and Applications
- Nonlinear Optical Materials Studies
- Optical Coatings and Gratings
- Gear and Bearing Dynamics Analysis
- Pharmaceutical and Antibiotic Environmental Impacts
Zhejiang University
2021-2024
University of North Carolina at Chapel Hill
2019-2024
Research Center for Eco-Environmental Sciences
2021-2023
Chinese Academy of Sciences
2017-2023
University of Chinese Academy of Sciences
2017-2023
Henan Agricultural University
2023
Henan University
2023
Institute of Biophysics
2017
Center for Excellence in Education
2017
Zhejiang University of Technology
2004-2010
Streptomyces bacteria form reproductive aerial hyphae that are covered with a pattern of pairwise aligned fibrils called rodlets. The presence the rodlet layer requires two homologous rodlin proteins, RdlA and RdlB, functional amyloid chaplin ChpA-H. In contrast to redundancy shared among eight chaplins, both RdlB indispensable for establishment this structure. By using comprehensive biophysical approach combined in vivo characterization we found but not RdlA, readily assembles into fibrils....
Fei Loua, Tigran M. Abramyanb, Haiyan Jiaa, Alexander Tropshab & Alan Jonesac* a Departments of Pharmacology, University North Carolina at Chapel Hill, NC, USA; b Division Chemical Biology and Medicinal Chemistry, UNC Eshelman School Pharmacy, c USA
Segregated pathways enable AtRGS1 endocytosis to transduce signal-specific responses in Arabidopsis .
Electrical energy consumption per order (EEO) is an important figure-of-merit for the selection and optimization of ultraviolet (UV)-based advanced oxidation processes (UV-AOPs). However, EEO applications are limited by lack accurate facilitative evaluation method because presents reactor property dependence. In this study, we developed prediction multiscale UV-AOP reactors micropollutant removal in water. The utilized reaction rate constants determined a reference (e.g., mini-fluidic...
The curvature of the NURBS curve varies along its trajectory, therefore, commonly used feedrate-planning method, which based on acceleration/deceleration (Acc/Dec) model, is difficult to be directly applied in CNC machining a curve. To address this problem, method critical constraint feedrate (CCC) proposed. Firstly, problems existing methods and their causes are analyzed. Secondly, by considering both kinematic during Acc/Dec process, concept CCC represents relationship between...
Extracellular signals perceived by 7-transmembrane (7TM)-spanning receptors initiate desensitization that involves the removal of these from plasma membrane. Agonist binding often evokes phosphorylation in flexible C-terminal region and/or intracellular loop 3 many 7TM G-protein-coupled animal cells, which consequently recruits a cytoplasmic intermediate adaptor, β-arrestin, resulting clathrin-mediated endocytosis (CME) and downstream signaling such as transcriptional changes. Some undergo...
A novel lapping mode is developed on the base of present eccentric v-grooves for precise balls. The kinematics analysis shows that ball spin axis can wiggle up to 180° under mode, so trace will be dispersed onto whole surface ball. effect offsetting and groove radius uniformity in v-grooves, traditional are compared, advantage impact less while has no impact.
9Cr18 is a type of martensite stainless steel. It has high hardness, chemical stability, fine anticorrosion, wearable and quench stability. been used in different areas with high-anticorrosion polishing surface as mirror. So it requires for the level quality after lapping polishing. In this paper, (surface roughness flatness) discussed parameters which include velocity, load time distribution two steps(rough Ultra-precision lapping). order to optimize those parameters, an optimization...
Potassium Titanium Oxide Phosphate (KTP) is a new nonlinear frequency-conversion crystal. It has chemical stability, high coefficient, damage threshold, easily-polished surface, and broad transparency range. be used in solid green laser with medium low power widely. The requirement for surface roughness less than 1nm.In this paper, the removal rate are discussed different velocity, pressure size of abrasive powder. In order to satisfy requirement, polishing techniques ultra-precision plane...
A generic co-expression strategy for site-specific incorporation of a single donor-acceptor dye pair into any position in dimeric protein, allowing molecule FRET study proteins previously inaccessible to this technique, such as the intrinsically disordered prion N-domain Ure2 context its globular C-domain.
Streptococcus suis seriously harms people and animals, importantly, causes great economic losses in the pig industry. Similar to most Gram-positive pathogenic bacteria, sortase A (SrtA) of S. can mediate anchoring a variety virulence factors that contain specific sorting sequences surface bacterial cell wall envelope participate pathogenicity. The purpose this study is clarify molecular mechanism epigallocatechin-3-gallate (EGCG) inhibiting SrtA provide more evidence for development novel...
STAVAX ESR(S-136)is a type of high stainless steel, used in precision mould widely . It has fine anticorrosion, polishing-alike, wearable,good process capacity and quench stability. To obtain the smooth surface ESR, material removal mechanism paper is discussed. The experiment processed on ultra-precision plane polishing machine (Nanopoli-100). processes are as follows. Rough lapping Ultra-precision lapping: pads cast iron. #1000Al203 (10wt%) abrasive powders rough lapping. Finally,...
ABSTRACT Plants uniquely have a family of proteins called extra-large G (XLG) that share homology in their C-terminal half with the canonical Gα subunits; we carefully detail here Arabidopsis XLG2 lacks critical residues requisite for nucleotide binding and hydrolysis which is consistent our quantitative analyses. Based on microscale thermophoresis, binds GTPγS an affinity 100-1000 times lower than to subunits. This means given concentration range guanine plant cells, not likely bound by GTP...
Chemical mechanical polishing has emerged recently as an indispensable processing technique in large scale integration. In chemical and process, principle is the vital factor removal process. Little known about what occurring beneath a wafer during Mechanical Polishing (CMP) processes. The paper provides LIF technology to visualize fluid flow between pad. this paper, experiment setup built. And then, images of fluorescence intensity excited by have been obtained from CCD. Finally,...
The ultra-precision lapping processes to obtain the damage-free surfaces at Å level surface roughness of Potassium titanyl phosphate (KTiOPO4, KTP) crystal is studied in this paper. influence parameters on stoke removal rate and material mechanism process discussed, evolution lapped also observed with electric telescope. A super-smooth quartz Ra 0.8667 has been obtained by adopting fine SiO2 abrasive powders elastic polyurethane pad study.
When the CNC machining of continuous small line segments is performed, direction machine tool movement will change abruptly at corner adjacent segments. Therefore, a reasonable constraint on feedrate prerequisite for achieving high-speed and high-precision machining. To achieve this goal, feedrate-constraint method based nominal acceleration was proposed. The proposed obtains predicted value during process by trajectory prediction filtering. Then, constrained, according to acceleration....