A5017074579- Inflammatory Bowel Disease
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Gallbladder and Bile Duct Disorders
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Autoimmune and Inflammatory Disorders
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Diagnosis and treatment of tuberculosis
- Liver Disease Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- Microscopic Colitis
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Amoebic Infections and Treatments
- Colorectal and Anal Carcinomas
- Autoimmune Bullous Skin Diseases
- Gastrointestinal Bleeding Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Chronic Lymphocytic Leukemia Research
- Foreign Body Medical Cases
- COVID-19 Clinical Research Studies
- Colorectal Cancer Screening and Detection
Hospital Universitario Río Hortega
2020-2025
Hospital Universitario Infanta Leonor
2024-2025
Hospital Universitario de Torrejón
2025
The Japanese Society of Gastroenterological Surgery
2021
Iwate Medical University
2021
Showa University
2021
Jikei University School of Medicine
2021
Abstract Background and Aims Clinical trials real-life studies with ustekinumab in Crohn’s disease [CD] have revealed a good efficacy safety profile. However, these data are scarcely available elderly patients. Therefore, we aim to assess the effectiveness of patients CD. Methods Elderly [>60 years old] from prospectively maintained ENEIDA registry treated due CD were included. Every patient was matched two controls under 60 age, according anti-tumour necrosis factor use smoking...
Carriers of the human leucocyte antigen variant HLADQA1*05 (rs2097432) are at risk developing antibodies against infliximab and adalimumab with reduced tumor necrosis factor (TNF) antagonist persistence. The impact proactive therapeutic drug monitoring (PTDM) on this association has been barely assessed.We conducted a retrospective single-center cohort study including patients inflammatory bowel disease starting anti-TNF therapy between January 2017 March 2021. Proactive was defined as...
Abstract Background Upadacitinib has shown to be more effective than placebo for treating extraintestinal manifestations (EIM) in post-hoc analyses. However, real-world data on the effectiveness of upadacitinib patients with inflammatory bowel disease (IBD) and EIMs are lacking. Methods A multicenter, retrospective observational study was conducted at 18 Spanish hospitals. Patients IBD active when initiating were eligible. The primary outcome EIM improvement weeks 8-12. assessment based...
We present an interesting case of severe ulcerative colitis flare, challenging management because a cytomegalovirus co-infection, in which upadacitinib achieved clinical and biochemical remission after poor responses to ganciclovir tofacitinib.
Background/Objectives: Data on the natural history and endoscopic treatment outcomes of recurrent anastomotic biliary stricture (RABS) after orthotopic liver transplantation (OLT) are limited. This study aimed to evaluate incidence RABS OLT. Methods: A retrospective single-center OLT patients who underwent successful ABS was conducted. The RABS, risk factors for recurrence, repeat therapy were recorded. Results: total 131 with treatment, which 119 successfully completed an course. After a...
Clinical trials have demonstrated the efficacy and safety of ustekinumab in Crohn's disease (CD). However, more data are necessary on effectiveness bio-naïve patients real-life studies.The aim our study was to evaluate with CD refractory or intolerant conventional therapy without previous exposure biological drugs.We performed a nationwide, observational, retrospective, multicentre including CD, which used as first drug.The corticosteroid-free clinical response remission were analysed at...
The impact of biologics on the risk postoperative complications (PC) in inflammatory bowel disease (IBD) is still an ongoing debate. This lack evidence more relevant for ustekinumab and vedolizumab.To evaluate PC.A retrospective study was performed 37 centres. Patients treated with within 12 weeks before surgery were considered "exposed". exposure 30-day PC infections assessed by logistic regression propensity score-matched analysis.A total 1535 surgeries 1370 patients. Of them, 711...
Intra-abdominal abscesses complicating Crohn's disease [CD] are a challenging situation. Their management, during hospitalisation and after resolution, is still unclear. Adult patients with CD complicated intra-abdominal abscess. who required hospitalisation, were included from the prospectively maintained ENEIDA registry GETECCU. Initial strategy effectiveness safety to resolve abscess was assessed. Survival analysis performed evaluate recurrence risk. Predictive factors associated...
different endoscopic procedures have been proposed for the management of surgical leaks. Endoscopic internal drainage using trans-fistulary double-pigtail plastic stents has emerged as an alternative strategy, especially in fistulae presenting after laparoscopic gastric sleeve.a retrospective case series was performed at a single tertiary care center including all upper gastrointestinal post-surgical leaks primarily managed with insertion stents. Clinical success defined absence...
Obesity is considered a risk factor for perioperative complications, but its effect on patients undergoing liver transplantation (LT) remains unclear. This study was conducted to analyze the impact of obesity early morbidity and mortality following LT.A multicenter outcomes in submitted LT between 2009 2019 conducted. Recipients were stratified into obese (BMI ≥ 30 kg/m2) nonobese < kg/m2). Early postoperative complications compared 30-day 1-year patient graft survival assessed by...
Abstract Background Ustekinumab (UST) is usually employed in Crohn’s disease (CD) after anti-tumor necrosis factor (TNF) therapy failure or if anti-TNF contraindicated. Higher UST trough levels have been associated with better clinical/endoscopic outcomes, so dose escalation (reducing dosing intervals reinduction) widely used. Intravenous (iv) maintenance has proposed, but it barely assessed. Methods Single center, retrospective case series. All patients CD starting treatment and receiving...
The evidence suggests that most vulnerable subjects to COVID-19 infection suffer from patients with comorbidities or immunosuppression, including liver transplant recipients. Liver graft dysfunction may be a rare complication. Some complain about the post-COVID-19 syndrome. aim of this study was assess medium- and short-term outcomes in patients.A retrospective case series performed at tertiary referral center. We screened 845 who had (LT) our All consecutive LT during Spanish outbreak March...
Abstract Background Inflammatory bowel disease (IBD) is a chronic condition of the gastrointestinal tract. Around 20% patients develop at least one extraintestinal manifestation, most frequent being articular, followed by cutaneous and ocular. Among those involving skin, erythema nodosum (EN) pyoderma gangrenosum (PG) are frequently observed. Methods Our aim was to describe characteristics PG EN in both ulcerative colitis (UC) Crohn’s (CD), provide detailed description their treatment,...
Abstract Background Few small studies have assessed the efficacy of topical therapy with tacrolimus in patients ulcerative colitis (UC). The aim our study was to evaluate its effectiveness and safety a real-world setting. Methods A multicenter observational retrospective at 25 Spanish GETECCU hospitals performed. Adult UC who received from January 2009 2023 were eligible. Inclusion criteria proctitis, left-sided, or extensive persistent distal colonic activity confirmed endoscopically during...