A5103263620- Wound Healing and Treatments
- Head and Neck Surgical Oncology
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Spinal Dysraphism and Malformations
- Periodontal Regeneration and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Corneal Surgery and Treatments
- Urological Disorders and Treatments
- Surgical Sutures and Adhesives
- Tracheal and airway disorders
- Cerebrospinal fluid and hydrocephalus
- Silk-based biomaterials and applications
- Soft Robotics and Applications
- 3D Printing in Biomedical Research
- Diagnosis and Treatment of Venous Diseases
- Shoulder Injury and Treatment
- Bone Tissue Engineering Materials
- Tendon Structure and Treatment
- Urologic and reproductive health conditions
- Pelvic floor disorders treatments
- Pituitary Gland Disorders and Treatments
- Glioma Diagnosis and Treatment
Institute of Remote Sensing and Digital Earth
2021-2022
The University of Texas at El Paso
2016-2019
Tsinghua University
2015-2017
Background: This study aims to design a 3D printed handheld electrospinning device and evaluate its effect on the rapid repair of mouse skin wounds. Methods: The was developed by Solidworks Object 350 photosensitive resin printer. polylactic acid (PLA)/gelatin blend used as raw material fabricate in-situ degradable nanofiber scaffolds. Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), water vapor permeability test were properties...
Biomimetic design will significantly improve growth and regeneration of dural cells tissue for better repairing effects fewer complications in the native dura. This study designed a novel composite, biomimetic substitute based on characteristics dura extracellular matrix.This is expected to rapidly induce cell adhesion, migration, fast neotissue. The material (contact angle, surface charge, zeta potential were evaluated), vitro biological (cell stretch, connections between cells,...
Background: Numerous dura substitutes are commercially available, but no absorbable synthetic repair product has been used for both onlay and suture applications.Objective: The safety effectiveness of a new substitute composed Poly-L-lactide microfibers as dural graft were evaluated.Methods: Physical properties performance the microfibrous implanted an or suturable grafts compared with these commercial products, including CODMAN ETHISORB™ Dura Patch DuraGen™ Dural Graft Matrix, in canine...
Dural repair products are evolving from animal tissue-derived materials to synthetic as well inert absorbable features; most of them lack functional and structural characteristics compared with the natural dura mater. In present study, we evaluated properties tissue performance a new dural product biomimetic design. The patch exhibits unique three-dimensional nonwoven microfiber structure good mechanical strength biocompatibility. study showed that commercially material group presented...
Objective: This case series evaluates the safety and effectiveness of 3D-printed scaffold in chronic wounds. The is a composite natural synthetic materials, can be prepared form powder or membrane. Method: We recruited patients with pressure ulcera (PU) and/or diabetic foot ulcers (DFU). used two methods: scaffolds alone, 3D-printing mixed platelet-rich fibrinogen (PRF). Clinicians were asked to rate scaffold's ease application comfort during use. Results: A total five recruited; four PU one...
Growth-hormone-secreting pituitary adenoma (GHSPA) is a benign tumour with high incidence and large economic burden, which greatly affects quality of life. The aetiological factors are yet to be clarified for GHSPA. Conventional two-dimensional (2D) monolayer culture cells cannot ideally reflect the growth status tumours in physiological environment, insufficiencies vitro models have severely restricted progress cancer research. Three-dimensional (3D) bioprinting technology being...
This research was set up to determine the efficacy of a synthetic biomimetic skin substitute poly-L-lactide (PLLA)/gelatin nanofiber membrane in facilitating chronic cutaneous wound healing. The material physical properties and biological characteristics were evaluated. safety effectiveness further confirmed by clinical applications. Results indicated that average diameter nano pores 0.65 μm. mean contact angle 80.39°, tensile strength 4.42 ± 0.43 MPa. proliferation fibroblasts monocytes...
The aim of this study is to investigate the feasibility and efficacy a novel biomimetic poly-l-lactide (PLLA) nanofiber membrane in repairing anterior urethral strictures from both preclinic clinic. Biomimetic PLLA was fabricated layer by according structure human extracellular matrix. Microstructure, tensile strength, suture retention strength were fully assessed. Before clinical application, safety toxicology test performed vitro experimental animals. patients underwent urethroplasty used...
To evaluate the safety and effectiveness of polylactic acid/gelatin nanofibre membranes (PGNMs) in treating hard-to-heal lower extremity venous ulcer wounds.In this prospective study, patients with leg ulcers (VLUs) were treated PGNMs or standard care. Wounds assessed once a week until wound was fully healed.The treatment group comprised 10 VLUs, aged between 47-64 years, an average age 56.58±6.19 years. The wounds located and/or ankle. Average area 8.91±13.57cm2 (range: 1.5-52.5cm2)....
Objective: To evaluate the histocompatibility of an original Chinese-made mid-urethral sling (Repelvica sling). Methods: In total 10 female New Zealand white rabbits were implanted with Repelvica or tension-free vaginal tape-obturator tape (TVT-O; Gynecare). Both brands under deep fascia abdominal wall and in space between vagina bladder. All animal groups sacrificed at set time intervals (4 weeks 12 weeks), slings harvested for histological evaluation. Results: appeared to be well...