- Laser-Matter Interactions and Applications
- Laser-Plasma Interactions and Diagnostics
- Perovskite Materials and Applications
- Polysaccharides and Plant Cell Walls
- Conducting polymers and applications
- Advanced Fiber Laser Technologies
- Wound Healing and Treatments
- Physics of Superconductivity and Magnetism
- Superconductivity in MgB2 and Alloys
- Immunotherapy and Immune Responses
- 3D Printing in Biomedical Research
- Organic Light-Emitting Diodes Research
- Rare-earth and actinide compounds
- Advancements in Transdermal Drug Delivery
- CAR-T cell therapy research
- Inorganic Fluorides and Related Compounds
- Microbial Metabolites in Food Biotechnology
- Orbital Angular Momentum in Optics
- Seaweed-derived Bioactive Compounds
- Nanoplatforms for cancer theranostics
- Mass Spectrometry Techniques and Applications
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Ginger and Zingiberaceae research
- Photonic and Optical Devices
University of Chinese Academy of Sciences
2009-2025
Zhejiang Lab
2021-2025
Shenzhen Technology University
2024
Lishui Central Hospital
2024
Wenzhou Medical University
2020-2024
Zhejiang Shuren University
2024
Nanjing Drum Tower Hospital
2022-2024
Nanjing University of Chinese Medicine
2024
Advanced Neural Dynamics (United States)
2024
Nanyang Technological University
2022-2023
Immunotherapy has recently garnered significant research interest in the field of clinical cancer management. The potential tumor immunotherapy been demonstrated for targeting a variety tumors, both vivo and vitro, yielding some remarkable therapeutic effects. Herein, inspired by stem cell niche, we developed scale-up approach to generating porous microspheres with encapsulated natural killer (NK) cells via microfluidic electrospray situ immunotherapy. generated contained microstructures...
Abstract Emerging biologics, such as monoclonal antibodies (mAbs), are the most promising treatment for psoriasis, while their effective delivery to local inflammatory area of skin is a challenge. Here, novel photo‐thermally dissolvable hyaluronic acid microneedle patch presented with biologics IL‐17 mAbs and MXene encapsulation psoriasis treatment. As microneedles possess suitable mechanical strength great biocompatibility, they can puncture minimal immune response. In addition, owing...
Hydrogel dressings have received extensive attention for the skin wound repair, while it is still a challenge to develop smart hydrogel adapting dynamic healing process. Herein, we novel graphene oxide (GO) hybrid scaffold with adjustable mechanical properties, controllable drug release, and antibacterial behavior promoting healing. The was prepared by injecting benzaldehyde cyanoacetate group-functionalized dextran solution containing GO into collection pool of histidine. As possesses...
Microneedle patches have been extensively employed for wound healing, while the lack of rapid hemostasis efficiency and multiple tissue-repair properties restrict their values in hemorrhagic applications. Herein, we propose a Yunnan Baiyao-loaded multifunctional microneedle patch, namely (BY + EGF)@MN, with deep tissue penetration, regenerative healing. The EGF)@MNs are designed BY-loaded Bletilla striata polysaccharide (BSP) base epidermal growth factor (EGF)-loaded GelMA tips subsequent As...
Longan is a delicious subtropical fruit with great health-beneficial effects. It has been utilized for disease prevention and health care since ancient age. To explore the chemicals responsible benefits, water-soluble polysaccharides were extracted from longan flesh in this work. A pure polysaccharide (LPS1) was obtained through column purification. Analysis by gas chromatography showed LPS1 homopolysaccharide of glucose glycosidic linkage →6)-d-Glc-(1→. Nuclear magnetic resonance (NMR)...
The high-order harmonic generation process of ${\mathrm{H}}_{2}{}^{+}$ in a co-rotating two-color circularly polarized laser pulse was investigated by numerically solving the time-dependent Schr\"odinger equation. Compared with target atom, intensity is remarkably enhanced. Moreover, approaches its maximum when electric field amplitude ratio fundamental frequency and second one approximately 1:2.3. By analyzing evolution wave packets, enhancement may be attributed to an increase probability...
Reproduction is the most important event for continuation of life. Unfortunately, infertility a widespread problem. Recently, biomaterials have been widely used in reproductive biology, including tissue engineering, regenerative medicine and contraception. In this review, we summarize research progress applied follicle culture, artificial ovary, We first introduce applications advantages different culture ovary. Then, engineering biology. Also, Besides, some emerging technologies are also...
Abstract Extracellular vesicles (EVs) derived from immune cells have shown great anti-cancer therapeutic potential. However, inefficiency in EV generation has considerably impeded the development of EV-based basic research and clinical translation. Here, we developed a seesaw-motion bioreactor (SMB) system by leveraging mechanical stimuli such as shear stress turbulence for generating EVs with high quality quantity natural killer (NK) cells. Compared to production traditional static culture...
It is important to develop new antibiotics aimed at novel targets. The investigation found that the leaf extracts from five maples (Acer platanoides, Acer campestre, rubrum, saccharum and truncatum Bunge collected in Denmark, Canada China) their component tannic acid displayed antibacterial ability against 24 standard bacteria strains with minimum inhibitory concentration of 0.3-8.0 mg/mL. Unlike antibiotic levofloxacin (LFX), these samples inhibited Gram-positive more effectively than they...
Ganoderma is a large and diverse genus containing fungi that cause white rot to infect number of plant families. This study describes G. phyllanthicola suae as new species from Southwest China, based on morphological molecular evidence. characterized by dark brown purplish black pileus surface with dense concentric furrows, pale yellow margin, irregular pileipellis cells, small pores (5–7 per mm) ellipsoid sub-globose basidiospores (8.5–10.0 × 6.0–7.5 µm). reddish oxblood red lead gray...
Abstract A multifunctional polydopamine/mesoporous silica nanoparticles loaded cryptotanshinone (PDA/MSN@CTS) was synthesized and subjected to investigating its physicochemical properties anti‐gastric cancer (GC) effects. Utilizing network pharmacology molecular docking techniques, CTS identified as our final research target. The structural morphology of PDA/MSN@CTS were examined. Near‐infrared (NIR) laser employed evaluate the photothermal PDA/MSN@CTS, along with pH‐responsive NIR‐triggered...
Eupafolin is a flavonoid extracted from the common sage herb which has been used in China as traditional medicine.Previous studies had reported that eupafolin antioxidative, anti-inflammatory and antitumor effects.However, function mechanism of to exert its activity, especially effect on tumor angiogenesis, have not elucidated.Herein, we showed significantly inhibited vascular endothelial growth factor (VEGF)-induced cell proliferation, migration tube formation human umbilical cells (HUVECs)...
Abstract We theoretically investigate the ionization process of interaction between a strong circular polarized laser pulse and an atom, whose initial state has different orbital angular momenta. When rotation direction vector field is opposite to that bound state, probability significantly higher than co-rotating case, in which rotational electron. Especially, with increase incident laser’s wavelength, enhanced for it on contrary counter-rotating case. By analyzing electronic trajectories...