A5101570895- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Pharmacological Effects of Natural Compounds
- Pelvic and Acetabular Injuries
- Lymphatic System and Diseases
- Angiogenesis and VEGF in Cancer
- Cervical and Thoracic Myelopathy
- Reconstructive Surgery and Microvascular Techniques
- Cancer-related molecular mechanisms research
- Respiratory Support and Mechanisms
- Infectious Diseases and Tuberculosis
- Anesthesia and Pain Management
- Epilepsy research and treatment
- Cancer Mechanisms and Therapy
- Facial Trauma and Fracture Management
- Shoulder Injury and Treatment
- Fungal Biology and Applications
- Cannabis and Cannabinoid Research
- COVID-19 Clinical Research Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Ocular Infections and Treatments
- Sleep and Work-Related Fatigue
- Neuroscience and Neuropharmacology Research
- Pharmacovigilance and Adverse Drug Reactions
Qujing Normal University
2024
Kunming Medical University
2024
Gansu Provincial Hospital
2024
Chenzhou First People's Hospital
2005-2023
First Affiliated Hospital of Heilongjiang University of Chinese Medicine
2022
Southwest Forestry University
2022
University of South China
2018-2021
University of Kentucky
2018-2020
Southern Medical University
2020
First Affiliated Hospital of Soochow University
2006-2017
Abstract Background Extracellular matrix protein 1 (ECM1) and vascular endothelial growth factor-C (VEGF-C) are secretory glycoproteins that associated with lymphangiogenesis; these proteins could, therefore, play important roles in the lymphatic dissemination of tumors. However, very little is known about their potential lymphangiogenesis. The aim this study was to investigate whether correlations exist between ECM1 VEGF-C human breast cancer, lymphangiogenesis, clinicopathological...
Background Severe coronavirus disease 2019 (COVID -19) has led to severe pneumonia or acute respiratory distress syndrome (ARDS) worldwide. we have noted that many critically ill patients with COVID-19 present typical sepsis-related clinical manifestations, including multiple organ dysfunction syndrome, coagulopathy, and septic shock. The molecular mechanisms underlie COVID-19, ARDS sepsis are not well understood. objectives of this study were analyze potential identify drugs for the...
AIM:To study the expression of vascular endothelial growth factor A (VEGF -A) and VEGF -C to determine whether presence -A was associated with clinicopathologic characteristics pancreatic cancer. METHODS:VEGF mRNA transcripts were examined by Northern blot in 6 human cancer cell lines 8 normal tissues carcinoma specimens.The proteins Western tested immunohistochemical stain 50 samples. RESULTS:VEGF present all lines.Immunoblotting revealed lines.Northern analysis total RNA 3.0-fold 3.6 -fold...
Abstract Recently, several studies have reported that the pharmacological effects exerted by cannabidiol (CBD) are partially related to regulation of autophagy. Increasing evidence indicates autophagy provides protection against ischemia‐induced brain injury. However, protective effect CBD mitochondrial‐dependent apoptosis in hemorrhagic shock (HS)‐induced injury has not been studied. In present study, we observed neural a rat model HS. addition, increased Beclin‐1 and LC3II expression...
Assessing the safety and feasibility of chronic delivery compounds to brain using convection-enhanced (CED) is important for further development this therapeutic technology. The objective study was follow model distribution a compound delivered by CED into putamen rhesus monkeys.The authors sequentially implanted catheters 4 sites spanning left right in each 6 monkeys. were connected pumps, which programmed deliver 5-mM solution MRI contrast agent Gd-DTPA at 0.1 μl/minute 7 days 0.3 an...
Abstract Three new lanostanoid triterpenes named 3β,7β‐di‐ hydroxy‐11,15,23‐trioxo‐lanost‐8,16‐dien‐26‐oic acid (1), 3β,7β‐dihydroxy‐11,15,23‐trioxo‐lanost‐8,16‐dien‐26‐oic methyl ester (2), and 12β‐acetoxy‐3β,7β‐dihydroxy‐11,15,23‐trioxo‐lanost‐8,16‐dien‐26‐oic (3) were isolated from the fruit bodies of Ganoderma lucidum . They all show a Δ 16, 17 double bond unprecedented in such types possessing side chain at C‐17. The complete NMR assignments for these compounds carried out using 1 H, 13...
Glioblastoma is the most aggressive primary brain tumor that originates from glial cells in adults. Aberrant angiogenesis essential for malignant glioblastoma tumorigenesis, development and metastasis. Lenvatinib a multi‑targeted anticancer agent targets of receptor tyrosine kinases including vascular endothelial growth factor 1 2, fibroblast 1, platelet‑derived β v‑kit Hardy‑Zuckerman 4 feline sarcoma viral oncogene homolog. In present study, therapeutic effects lenvatinib as treatment were...
BACKGROUND Despite literature supporting the efficiency of percutaneous balloon kyphoplasty (PKP) in treating osteoporotic and malignant vertebral compression fractures, few reports exist that document its use for treatment symptomatic Schmorl's nodes (SNs) refractory to conservative treatment. Patients with SNs could have pain vertebrae similar an acute fracture. MRI is very helpful diagnosing when x-ray CT scan are unremarkable. In painful cases, bone marrow around hyperintense on...
Glucose‑regulated protein 75 (GRP75) is a member of the heat shock 70 family and previous studies have demonstrated that GRP75 involved in diseases central nervous system. However, biological function intracerebral hemorrhage (ICH) remains to be clarified. Thus, aim present study was evaluate effects rat model ICH. Western blotting used detect expression GRP75, active caspase‑3, Bax, Bcl‑2, p‑Akt Akt brain tissues following The levels tumor necrosis factor‑α (TNF‑α) interleukin (IL)‑1β were...
To investigate the value of modified ROX (mROX) index in predicting outcome patients with acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 infection treated high-flow nasal cannula oxygen therapy (HFNC).
Adipose-derived mesenchymal stem cells (ADSCs) have received significant attention in the field of cartilage tissue repair. Angelica sinensis polysaccharide (ASP) can enhance both proliferation and differentiation cells. Therefore, we intend to explore effect ASP on chondrogenic ADSCs vitro, elucidate underlying mechanisms.
胡奕 1,2)** 刘朋朋 2)** 张志明 3) 卢鹤真 2,4) 罗静 2)王承民 2) 刘军须 4) 赵宝华 1)*** 何宏轩 2)***( 1) 河北师范大学生命科学学院，石家庄 050016； 中国科学院动物研究所，国家野生动物疫病研究中心，北京 100101；3) 北京市野生动物救护中心，北京 100101； 河北省实验动物中心，河北省实验动物重点实验室，石家庄 050017)摘要 对高致病性禽流感病毒感染最为有效的治疗应采用抗病毒和抗炎症的联合治疗． 本试验用流感病毒 H5N1 感染不同细 胞株(A549 细胞和 MDCK 细胞)，采用不同浓度格尔德霉素对病毒感染细胞培养物作用不同时长，检测流感病毒滴度； ELISA 检测格尔德霉素作用于流感病毒 感染