- Palliative Care and End-of-Life Issues
- Patient Dignity and Privacy
- Childhood Cancer Survivors' Quality of Life
- Patient-Provider Communication in Healthcare
- Grief, Bereavement, and Mental Health
- Family and Patient Care in Intensive Care Units
- Health Systems, Economic Evaluations, Quality of Life
- Cancer survivorship and care
- Pharmacological Effects and Toxicity Studies
- Pharmaceutical Practices and Patient Outcomes
- Cancer Treatment and Pharmacology
- Cancer Risks and Factors
- Ethics in medical practice
- Anesthesia and Sedative Agents
- Pain Management and Opioid Use
- Drug Transport and Resistance Mechanisms
- Intensive Care Unit Cognitive Disorders
- Healthcare cost, quality, practices
- Pharmacogenetics and Drug Metabolism
- Geriatric Care and Nursing Homes
- Clinical practice guidelines implementation
- Family Support in Illness
- Pharmaceutical studies and practices
- Delphi Technique in Research
- Healthcare innovation and challenges
Amsterdam University Medical Centers
2021-2025
Vrije Universiteit Amsterdam
2021-2024
Cancer Center Amsterdam
2021-2024
Netherlands Center for Occupational Diseases
2021-2024
Amsterdam UMC Location Vrije Universiteit Amsterdam
2004-2024
University of Amsterdam
2021-2023
Erasmus MC Cancer Institute
2008-2022
Erasmus MC
2009-2022
General Department of Preventive Medicine
2021
Erasmus University Rotterdam
2009-2018
We studied the effect of Liverpool Care Pathway (LCP) on documentation care, symptom burden and communication in three health care settings. Between November 2003 February 2005 (baseline period), was provided as usual. 2006 (intervention LCP used for all patients whom dying phase had started. After death patient, a nurse relative filled questionnaire. In baseline period, 219 nurses 130 relatives questionnaire 220 deceased patients. intervention 253 139 255 The 197 them. significantly more...
To examine health professionals' experiences of and attitudes towards the provision chemotherapy to patients with end stage cancer.Purposive, qualitative design based on in-depth interviews. Setting Oncology departments at university hospitals general in Netherlands.14 physicians 13 nurses who cared for metastatic cancer.Physicians reported trying inform fully about their poor prognosis treatment options. They would carefully consider (side) effects sometimes doubted whether further...
Abstract Background During the first peak of COVID-19 pandemic in Netherlands, relatives patients with admitted to Intensive Care Units (ICUs) were severely restricted visiting their and communicating treating physicians. Family communication is a core element critical care, however, this forced medical ICU staff arrange alternative family support for instance by Support Teams (FSTs), consisting non-ICU affiliated who telephonically contacted relatives. This study aims examine relatives’...
<h3>Importance</h3> <i>Death rattle</i>, defined as noisy breathing caused by the presence of mucus in respiratory tract, is relatively common among dying patients. Although clinical guidelines recommend anticholinergic drugs to reduce death rattle after nonpharmacological measures fail, evidence regarding their efficacy lacking. Given that anticholinergics only decrease production, it unknown whether prophylactic application may be more appropriate. <h3>Objective</h3> To determine...
Good care of the dying has been defined as being able to die in place your choice, free from pain, cared for with dignity and supported by best possible care. This definition underpinned development '10/40 Model' dying, 2013. The model includes 10 'Key Principles' that underpin 40 'Core Outcomes' It was necessary update consensus on 10/40 Model ensure it remains clinically relevant applicable practice.Update international content Model.Delphi study utilising questionnaire completion; each...
Background Large, international cohort studies generate high-level evidence, but are resource intense. In end-of-life care such scarce. Hence, planning for future in terms of data on screening, recruitment, retention and survival remains a challenge. Objectives The aim was to describe follow-up multinational study patients’ relatives’ expectations, concerns preferences at the end life. Methods this 11-country with six months patients, >18 years old, were included basis an adapted...
Although guidelines advise titration of palliative sedation at the end life, in practice depth can range from mild to deep. We investigated physicians' considerations about continuous sedation.We performed a qualitative study which 54 physicians underwent semistructured interviewing last patient for whom they had been responsible providing sedation. also asked their practices and general attitudes toward found two approaches sedation: starting with only increasing if necessary, deep right...
In Brief BACKGROUND: Cisplatin is considered safe to use during the second and third trimesters of pregnancy in patients with cancer. CASE: A 34-year-old pregnant woman was diagnosed cervical She received five weekly dosages cisplatin paclitaxel, starting at 26 5/7 weeks gestation. An elective cesarean delivery performed 34 4/7 After birth, neonate severe bilateral perceptive hearing loss. CONCLUSION: may lead fetal ototoxicity. cause
At the end of life oral fluid intake is often reduced. Consensus about most appropriate management for terminally ill patients with limited lacking. The objective this study to investigate what extent amount intake, preceding and during dying phase, related occurrence death rattle terminal restlessness.A multicentre prospective observational was performed. Data on restlessness, opioid use expected die within a few days or hours were collected.371 included. Death reported at least once in 40%...
Purpose Involvement of palliative care experts improves the quality life and satisfaction with patients who are in last stage life. However, little is known about relation between expert involvement dying (QOD) hospital. We studied association team (PCT) consultation QOD hospital as experienced by relatives. Methods conducted a secondary analysis data from prospective study among relatives died cancer university compared characteristics for whom PCT was or not consulted. Results 175 out 343...