A5083885486- Plant Stress Responses and Tolerance
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Lipid metabolism and biosynthesis
- Alzheimer's disease research and treatments
- Algal biology and biofuel production
- Neuroinflammation and Neurodegeneration Mechanisms
- RNA modifications and cancer
- Resilience and Mental Health
- Genetics and Plant Breeding
- Stress Responses and Cortisol
- ATP Synthase and ATPases Research
- Sphingolipid Metabolism and Signaling
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Coenzyme Q10 studies and effects
- Eating Disorders and Behaviors
- Fibroblast Growth Factor Research
- Extracellular vesicles in disease
- Advanced Photocatalysis Techniques
- Polysaccharides and Plant Cell Walls
- MicroRNA in disease regulation
- Plant responses to elevated CO2
Shenzhen University
2019-2025
South China Agricultural University
2019-2024
South China Botanical Garden
2019-2024
Beijing Sport University
2017-2024
General Hospital of Guangzhou Military Command
2024
University of Chinese Academy of Sciences
2019-2023
China National Botanical Garden
2023
Chinese Academy of Sciences
2021-2023
State Key Laboratory of Plant Genomics
2021-2023
Third Affiliated Hospital of Southern Medical University
2021
Alzheimer’s disease (AD) is characterized by deficits in learning and memory. A pathological feature of AD the alterations number size synapses, axon length, dendritic complexity, spine numbers hippocampus prefrontal cortex. Treadmill exercise can enhance synaptic plasticity mouse or rat models stroke, ischemia, dementia. The aim this study was to examine effects treadmill on memory, structural 3×Tg-AD mice, a model AD. Here, we show that 12 weeks beginning three-month-old mice improves...
Abstract Background The regulation of lipid biosynthesis is essential in photosynthetic eukaryotic cells. This occurs during the direct synthesis fatty acids and triacylglycerols (TAGs), as well other controlling processes main carbon metabolic pathway. Results In this study, mRNA levels Chlamydomonas citrate synthase (CrCIS) were found to decrease under nitrogen-limited conditions, which suggests suppressed gene expression. Gene silencing by RNA interference (RNAi) was conducted determine...
Light functions as the primary environmental stimulus and brassinosteroids (BRs) important endogenous growth regulators throughout plant lifecycle. Photomorphogenesis involves a series of vital developmental processes that require suppression BR-mediated seedling growth, but mechanism underlying light-controlled regulation BR pathway remains unclear. Here, we reveal nuclear factor YC proteins (NF-YCs) function essential repressors during hypocotyl in Arabidopsis thaliana. In light, NF-YCs...
Abstract This study aimed to elucidate the clinical diagnostic value of plasma catecholamines and their metabolites for pheochromocytoma paraganglioma (PPGL)‐induced secondary hypertension using ultraperformance liquid chromatography‐mass spectrometry (UPLC‐MS/MS). The population included 155 patients with PPGL that were divided into ( n = 79) a without 76) groups, 90 healthy volunteers primary as control groups. UPLC‐MS/MS was performed detect levels metabolites, including dopamine,...
Purpose The role of exercise to prevent or reverse aging-induced cognitive decline has been widely reported. This neuroprotection is associated with changes in the synaptic structure plasticity. However, mechanisms exercise-induced plasticity aging brain are still unclear. Thus, aim present study investigate aging-related alterations Rho-GTPase and modulatory influences training. Methods Young old rats were used this study. Old subjected different schedules aerobic (12 m/min, 60 min/d, 3d/w...
Physical exercise improves memory and cognition in physiological aging Alzheimer’s disease (AD), but the mechanisms remain poorly understood. Here, we test hypothesis that Aβ oligomer accumulation, neuroinflammation, glial cell activation may lead to disruption of synaptic transmission prefrontal cortex 3 × Tg-AD Mice, resulting impairment learning memory. On other hand, treadmill could prevent pathogenesis exert neuroprotective effects. used immunohistochemistry, western blotting,...
Accumulating evidence underscores exercise as a straightforward and cost-effective lifestyle intervention capable of mitigating the risk slowing emergence progression Alzheimer’s disease (AD). However, intricate cellular molecular mechanisms mediating these exercise-induced benefits in AD remain elusive. The present study delved into impact treadmill on memory retrieval performance, hippocampal synaptic plasticity, morphology, expression activity...
Increasing concentration of CO2 has significant impacts on many biological processes in plants, and its impact is closely associated with changes the ratio photosynthesis to photorespiration. Studies have reported that high can promote carbon fixing alleviate plant oxidative damage response environmental stresses. However, effect fatty acid (FA) metabolism cellular redox balance FA-deficient plants rarely reported. In this study, we identified a high-CO2 -requiring mutant cac2 through...
WD40 repeat-containing protein (WD40 protein) acts as versatile scaffolds for interactions and participates in a variety of biological processes, such plant stress hormone responses. In recent study, we show that XPO1-Interacting 1 (XIW1) is nuclear accumulated by abscisic acid (ABA), which interacts with ABA insensitive 5 (ABI5) the nucleus maintains its stability, thereby affecting seed germination seedling growth. Here, XIW1 promotes salt inhibition (SSG). Mutation reduced induction ABI5...
A decline in cardiovascular modulation is a feature of the normal aging process and associated with diseases such as hypertension stroke. Exercise training known to promote adaptation young animals positive effects on motor cognitive capabilities, well brain plasticity for all ages mice. Here, we examine question whether aerobic exercise interventions may impact GABAergic neurons paraventricular nucleus (PVN) aged rats which have been observed integration function. In present study, (2...
Translocase of inner mitochondrial membrane 17A (TIMM17A) is overexpressed in breast cancer (BRCA), and upregulation can increase the aggressiveness BRCA cells. This study examined influence TIMM17A gene network on outcome.Expression levels were compared between normal tumor tissues from OncomineTM database, association with patient survival was analyzed using Kaplan-Meier Plotter. Clinical factors influencing expression studied by UALCAN. cBioPotal then used to identify genes interacting...
ABSTRACT Photorespiration is a complex metabolic process linked to primary plant metabolism and influenced by environmental factors, yet its regulation remains poorly understood. In this study, we identified the asprs3‐1 mutant, which displays photorespiratory phenotype with leaf chlorosis, stunted growth, diminished photosynthesis under ambient CO 2 , but normal growth elevated conditions. Map‐based cloning genetic complementation AspRS3 as mutant gene, encoding an aspartyl‐tRNA synthetase....
Abstract: Bladder cancer is one of the most commonly diagnosed cancers worldwide and causes highest lifetime treatment costs per patient. likely to metastasize through lymphatic ducts, once lymph nodes are involved, prognosis poorly finitely improved by current modalities. The underlying metastatic mechanism for bladder thus becoming a research focus date. To identify relevant published data, an online search PubMed/Medline archives was performed locate original articles review regarding...