A5100786467- Dialysis and Renal Disease Management
- Parathyroid Disorders and Treatments
- Birth, Development, and Health
- Chronic Kidney Disease and Diabetes
- Nutrition and Health in Aging
- Advanced oxidation water treatment
- Genetic Syndromes and Imprinting
- Acute Kidney Injury Research
- Plant and Fungal Interactions Research
- Research in Cotton Cultivation
- Renal Diseases and Glomerulopathies
- Ion Transport and Channel Regulation
- Parkinson's Disease and Spinal Disorders
- Natural Antidiabetic Agents Studies
- RNA Research and Splicing
- Caveolin-1 and cellular processes
- Nosocomial Infections in ICU
- Industrial Gas Emission Control
- Urinary Bladder and Prostate Research
- Health, Environment, Cognitive Aging
- Toxic Organic Pollutants Impact
- NF-κB Signaling Pathways
- Skin Protection and Aging
- Effects and risks of endocrine disrupting chemicals
- Environmental remediation with nanomaterials
Anhui University of Science and Technology
2025
Fudan University
2010-2024
Huashan Hospital
1998-2024
Guangzhou University of Chinese Medicine
2024
Jilin Jianzhu University
2024
MaineHealth
2024
Guizhou Provincial People's Hospital
2015
Central South University
2010-2014
Third Xiangya Hospital
2010-2014
Zhejiang University
2011
<b><i>Background:</i></b> Residual kidney function (RKF) has consistently been a predictor of greater survival in maintenance hemodialysis (MHD) patients. The relationship between (HD) treatment frequency and RKF preservation not well examined. We hypothesized that initial twice-weekly HD helps maintaining longer RKF. <b><i>Methods:</i></b> In dialysis center Shanghai, 168 ESRD patients were screened finally 85 identified for this main cohort...
Angiogenesis plays an important role in the pathogenesis of diabetic nephropathy (DN). In present study, we investigated therapeutic potential resveratrol, a polyphenol with antiangiogenic activity DN. type 1 rat model, resveratrol treatment blunted increases urine albumin excretion, kidney weight and creatinine clearance rate. The glomerular diameter, mesangium accumulation, basement membrane thickness renal fibrosis rats were also reduced by treatment. kidney, increased expression vascular...
Diabetes is one of the most costly chronic diseases and increasing in epidemic proportions developing countries. It has been found that some antioxidants play a role protection against oxidative stress, which associated with diabetes. In this study, enzyme-released feruloyl oligosaccharides from wheat bran were given intragastrically (ig) to test their effect on antioxidant capacity, body weight restoring serum glucose level alloxan-induced diabetic Sprague−Dawley (SD) rats, using sodium...
BackgroundUrinary excretion of bisphenol A (BPA) and alkylphenols (APs) was used as a biomarker in most previous studies, but no study has investigated whether urinary these environmental phenols differed by renal function.ObjectiveWe estimated the association between function BPA APs.MethodsAnalyses were conducted using data from National Health Nutrition Examination Survey (NHANES) 2003–2006. Renal measured glomerular filtration rate (eGFR) calculated Modification Diet Disease (MDRD) Study...
Introduction.Acute kidney injury (AKI) is a major complication in patients with sepsis and an independent predictor of mortality. However, the optimal intensity renal replacement therapy for such still controversial.
The authors examined the association between cigarette smoking and risk of erectile dysfunction among 7,684 Chinese men aged 35–74 years without clinical vascular disease. Cigarette were assessed by questionnaire. Vascular factors measured according to standard methods. After adjustment for age, education, alcohol consumption, physical inactivity, diabetes, hypertension, overweight, hypercholesterolemia, odds ratio was 1.41 (95% confidence interval (CI): 1.09, 1.81) smokers compared with...
As a noninvasive examination, urinary proteomics is very useful tool to identify renal disease. The purpose of the present study was find differential proteins among women with preeclampsia, gestational hypertension and normal pregnancy, screen potential biomarkers for early diagnosis preeclampsia.Urinary were identified by iTRAQ labeling coupled 2-D LC-MS/MS. bioinformatics analysis performed Metacore software International Protein Index (IPI) Gene Ontology (GO) Database. differentially...
BACKGROUND Inguinal hernias are common after surgery. Tension-free repair is widely accepted as the main method for managing inguinal hernias. Adequate exposure, coverage, and of myopectineal orifice (MPO) necessary. However, due to differences in race sex, people’s body shapes vary. According European guidelines, patch should measure 10 cm × 15 cm. If any part MPO dissected, injury nerves, vascular network, or organs may occur during surgery, thereby leading discomfort, pain, seroma...
Secondary hyperparathyroidism (SHPT) in uremic patients is characterized by parathyroid gland (PTG) hyperplasia and hormone (PTH) elevation. Previously, we demonstrated that NF-κB activation contributed to cell proliferation rats with chronic kidney disease. Although vitamin D inhibits inflammation ameliorates SHPT, the contribution of deficiency SHPT via local remains be clarified. PTGs collected from 10 advanced were used test expressions receptor (VDR), NF-κB, proliferating nuclear...
Abstract Low-protein diet plus ketoacids (LPD+KA) has been reported to decrease proteinuria in patients with chronic kidney diseases (CKD). However, the mechanisms have not clarified. As over-activation of intrarenal renin–angiotensin system (RAS) shown play a key role progression CKD, current study was performed investigate direct effects LPD+KA on RAS, independently renal haemodynamics. In this study, 3/4 subtotal ablated rats were fed 18 % normal-protein (Nx-NPD), 6 low-protein (Nx-LPD)...
Objective. There is a high prevalence of sarcopenia in maintenance hemodialysis (MHD) patients, which known to be associated with increased mortality. This study aimed at analyzing the risk factors affecting muscle mass decline MHD patients. Methods. retrospective included patients who underwent two body composition assessments October 2013 and November 2017. Depending on whether there was loss or not, were divided into normal (NMM) group (MMD) group. According rate, MMD further classified...
The present study aimed to investigate the distribution of paired box 2 (PAX2) gene polymorphisms in healthy populations and patients with Henoch‑Schönlein purpura (HSP), focusing on association between PAX2 susceptibility clinical characteristics HSP. Genomic DNA was extracted from peripheral venous blood 100 children (mean age: 5 ± 1.9 years) 118 HSP 10.2 2.3 years). Polymerase chain reaction (PCR) used amplify exons 1‑12 gene. Denaturing high performance liquid chromatography sequencing...
Cryptic transcription initiation has been previously linked to activation of oncogenic transcripts. However, the prevalence and impact cryptic antisense from opposite strand protein-coding genes were mostly unknown in cancer. Applying a robust computational pipeline publicly available transcriptome epigenome datasets, we identified hundreds unannotated polyadenylated transcripts (CAPTs) that enriched tumor samples. We showed was associated with increased chromatin accessibility active...
Secondary hyperparathyroidism (SHPT) is a frequent complication of chronic kidney disease (CKD) associated with morbidity and mortality. This study aims to identify potential biomarkers that may be used predict the progression SHPT elucidate molecular mechanisms pathogenesis at transcriptome level.We analyzed differentially expressed genes (DEGs) between diffuse nodular parathyroid hyperplasia patients from GSE75886 dataset, then verified DEG levels GSE83421 data file primary (PHPT)...
To overcome the limitations of Fe( ii )-activated percarbonate process for ACT removal, this study introduced cysteine as a complexing agent into )/SPC system and enhanced degradation efficiency ACT.
Abstract Parathyroid hormone (PTH) is secreted by the parathyroid glands (PTGs) and an important regulating mineral metabolism. Previous studies reported that high sodium diet will cause increase in serum PTH, but specific mechanism unknown. Consequently, present study aims to investigate effects mechanisms of on PTH synthesis secretion from PTGs. We developed a tissue culture model using normal rat PTGs, discovered elicited promoted concentration-dependent time-dependent secretion. Changes...
The purpose of this study was to explore the contribution each factor phosphorus metabolism network following diet intervention via Granger causality analysis.In study, a total six healthy male volunteers were enrolled. All participants sequentially received regular, low-, and high-phosphorus diets. Consumption lasted for five days, with 5-day washout period between different Blood urinary samples collected on fifth day consumption at 9 time points (00:00, 04:00, 08:00, 10:00, 12:00, 14:00,...