A5059959020- Lung Cancer Diagnosis and Treatment
- Salivary Gland Disorders and Functions
- Nutrition and Health in Aging
- Protein purification and stability
- Monoclonal and Polyclonal Antibodies Research
- Alzheimer's disease research and treatments
- Body Composition Measurement Techniques
- Antibiotic Use and Resistance
- Acute Ischemic Stroke Management
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Radiomics and Machine Learning in Medical Imaging
- interferon and immune responses
- Neurogenesis and neuroplasticity mechanisms
- Cardiovascular Function and Risk Factors
- Plant Reproductive Biology
- Neutrino Physics Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Antibiotic Resistance in Bacteria
- Medicinal Plant Pharmacodynamics Research
- Hippo pathway signaling and YAP/TAZ
- Polysaccharides and Plant Cell Walls
- Plant Molecular Biology Research
- Rheumatoid Arthritis Research and Therapies
- Vascular Procedures and Complications
WuXi AppTec (China)
2022-2025
Anhui Science and Technology University
2025
Anhui University of Science and Technology
2025
Ningxia Medical University
2022-2024
Zhejiang University
2010-2024
Huashan Hospital
2018-2024
First Affiliated Hospital Zhejiang University
2017-2024
SUNY Upstate Medical University
2024
Ningxia Center for Diseases Prevention and Control
2023-2024
Affiliated Hospital of Taishan Medical University
2024
// Jing Zhang 1, * , Ge Wang Shao-Jun Chu 2 Jin-Shui Zhu 1 Rui Wen-Wen Lu Li-Qiong Xia Yun-Min Wei Da Qun Sun Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 200233, China Gerontology, These authors have contributed equally to this work Correspondence to: Zhu, e-mail: zhujs1803@163.com Keywords: large tumor suppressor YAP, metastasis, prognosis, gastric cancer Received: June 28, 2015 Accepted: January 05, 2016 Published: February 22, ABSTRACT...
Abstract This study aimed to reveal the effects of increasing levels rubber seed cake (RSC) on growth performance, nutrient digestion metabolism, serum biochemical parameters, and rumen microbiota in Hu sheep. In this study, 48 sheep, weighing 17.01 ± 0.57 kg at 3 months age, were randomly divided into four treatments: 0% (RSC0%), 6% (RSC6%), 12% (RSC12%) 18% (RSC18%), with 12 sheep per group. Compared RSC0%, ADG DMI RSC6% RSC12% increased ( P > 0.05). The apparent digestibility OM EE...
The aim of this study was to investigate potential biomarkers Alzheimer's disease (AD). Changes in protein expression brain tissues from AβPP/PS1 transgenic mice were evaluated using two-dimensional gel electrophoresis combined with LC-MS/MS. A
Currently, both non-alcoholic fatty liver disease (NAFLD) and sarcopenia have attracted extensive attention in public health. However, the relationship between NAFLD remains unclear. This study aimed to clarify sex-specific association according Asian Working Group for Sarcopenia (AWGS).Dual-energy X-ray absorptiometry (DXA) hepatic ultrasonography were measured 578 participants (92 men 486 women) during their annual health examinations. Multivariate logistic regression models used explore...
Abstract Selective induction of tumor thrombus infarction is a promising antitumor strategy. Non‐persistent embolism due to non‐compacted and activated fibrinolytic system within the large blood vessels margin recurrence are main therapeutic bottlenecks. Herein, an erythrocyte membrane‐coated invisible acoustic‐sensitive nanoparticle (TXA+DOX/PFH/RBCM@cRGD) described, which can induce by precisely damaging vascular endothelium. It revealed that TXA+DOX/PFH/RBCM@cRGD effectively accumulate on...
There were limited studies specifically evaluating whether the difference of prevalence sarcopenia exists in men and women older adults from rural areas China. The aim this study was to compare between a area eastern China explore underlying causes.This included 1,105 participants aged 60-89 years. Muscle mass measured by bio-electrical impedance analysis. Hand grip strength Jamar Hydraulic Dynamometer. Sarcopenia diagnosed according Asian Working Group for Sarcopenia-2019 Consensus. Data...
Hepatocellular carcinoma (HCC) is a common malignancy with poor prognosis and high mortality. This study aimed to explore the oncogenic mechanisms of TRAF5 in HCC provide novel therapeutic strategy for HCC.Human cell lines (HepG2, HuH7, SMMC-LM3, Hep3B), normal adult liver epithelial cells (THLE-2), human embryonic kidney (HEK293T) were utilized. Cell transfection was performed functional investigation. qRT-PCR western blotting used detect mRNA expression TRAF5, LTBR, NF-κB protein...
The Microphthalmia-associated Transcription Factor (MITF) governs numerous cellular and developmental processes. In mice, it promotes specification differentiation of the retinal pigmented epithelium (RPE), in humans, some mutations MITF induce congenital eye malformations. Herein, we explore function regulation Mitf Drosophila development uncover two roles. We find that knockdown results displacement (RDis), a phenotype associated with abnormal formation. functions peripodial (PE), support...
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by sustained fibrotic lesions. Orally administered drugs usually fail to efficiently penetrate the tissue and reach lesions, resulting in low treatment efficiency. Luteolin (Lut) natural flavonoid, active metabolites of which possess antioxidant, anti‐inflammatory, anti‐fibrotic, anti‐apoptotic properties. In this study, nano‐formulation developed loading Lut into hyaluronidase...
Abstract Purpose To investigate the effect of total glucoside paeony (TGP) on gut microbiota in NOD mice with Sjögren’s syndrome (SS), using high-throughput sequencing 16SrRNA gene. Methods Twenty-four were randomly assigned to 4 groups (n = 6 per group): sham group receiving deionized water (0.4 ml), hydroxychloroquin TGP and + 0.4 ml hydroxychloroquin. Balb/c 6) used as a control group. After intragastric injection drugs for 8 weeks, feces collected Results The gene resulted 3686 OTUs, 10...
Background: To explore the role of qualitative and quantitative imaging features pulmonary subsolid nodules (SSNs) in differentiating invasive adenocarcinoma (IAC) from minimally (MIA) preinvasive lesions. Methods: We reviewed clinical records our institute October 2010 to December 2015 included 316 resected SSNs 287 patients: 260 pure ground-glass nodules, 47 part-solid with solid components ≤5 mm, 9 (GGNs) cystic airspaces. According pathologic review results, 307 addition nine GGNs...
Enterovirus 71 (EV71) is an etiological agent of hand foot and mouth disease can also cause neurological complications in young children. However, there are no approved drugs as yet to treat EV71 infections. In this study, we conducted antiviral drug screening by using a Food Drug Administration (FDA)-approved library. We identified five that showed dose-dependent inhibition viral replication. Sertraline was further characterized because it exhibited the most potent activity with highest...
In order to discover and identify the key protein biomarkers in aging process, we performed a differential proteomic analysis of hippocampus cortex 5- 15-month old senescence-accelerated mouse prone 8 (SAMP8) as well control stra
The aim of this study is to identify and validate protein change in the serum from PD patients. We used samples 21 patients 20 age-matched normal people as control conduct a comparative proteomic study. performed 2-DE analyzed differentially expressed spots by LC-MS/MS. In group 13 were shown be compared group. They identified 6 proteins. Among these, 3 proteins confirmed Western blot analysis. It showed that frequency fibrinogen γ-chain (FGG) appeared 70% PD, which could not detected...
Abstract This study aims to evaluate the application of color Doppler ultrasound in monitoring complications autologous arteriovenous fistula hemodialysis patients. Patients with maintenance who underwent were enrolled this cross-sectional study. Ultrasound was used detect (stenosis and thrombosis), brachial artery diameter, hemodynamic parameters. The parameters analyzed screened identify most important indicator for complications. In all, 89 patients included. showed 72 cases (80.90%) had...