A5008958000- Reproductive Biology and Fertility
- Sirtuins and Resveratrol in Medicine
- Adipose Tissue and Metabolism
- Ovarian function and disorders
- Peroxisome Proliferator-Activated Receptors
- Assisted Reproductive Technology and Twin Pregnancy
- Insurance, Mortality, Demography, Risk Management
- Reproductive Health and Technologies
- Lipid metabolism and biosynthesis
- Genetics, Aging, and Longevity in Model Organisms
- Hormonal Regulation and Hypertension
- Biochemical effects in animals
University of L'Aquila
2013-2016
SUMMARY ANSWERSIRT1 plays a pivotal role in the adaptive response of mouse germinal vesicle (GV) oocytes to OS and promotes signalling cascade leading up-regulation MnSod gene.
Nowadays, human oocytes/embryos are cryopreserved via slow freezing or vitrification. The aim of this study was to evaluate a rapid warming protocol for slow-frozen oocytes based on the standard procedure This prospective 216 sibling randomized either conventional thawing with vitrification solution. primary endpoint morphological assessment survival at 2h. Surviving were divided into two subgroups: (i) parthenogenetically activated; and (ii) fixed observed spindle/chromosome configuration....
Controlled ovarian stimulation (COS) leading to ovulation of multiple follicles is a crucial aspect biomedical infertility care. Nevertheless, biomarkers useful for COS management are still lacking. Peroxisome proliferator-activated receptors (PPARs) nuclear hormone relevant steroid metabolism in granulosa cells (GCs). We investigated whether PPARs and their steroidogenic targets were differentially expressed GCs differentiated under different recombinant or urinary gonadotropin...