A5015801925- Collagen: Extraction and Characterization
- Bone Tissue Engineering Materials
- Silk-based biomaterials and applications
- Advanced biosensing and bioanalysis techniques
- Protein Hydrolysis and Bioactive Peptides
- biodegradable polymer synthesis and properties
- Meat and Animal Product Quality
- 3D Printing in Biomedical Research
- Nanopore and Nanochannel Transport Studies
- DNA and Nucleic Acid Chemistry
- Marine Biology and Environmental Chemistry
- Electrospun Nanofibers in Biomedical Applications
- Carbon and Quantum Dots Applications
- Supercapacitor Materials and Fabrication
- Proteins in Food Systems
- Periodontal Regeneration and Treatments
- Chemical Synthesis and Reactions
- Tendon Structure and Treatment
- Nanocluster Synthesis and Applications
- Wound Healing and Treatments
- Advanced Battery Materials and Technologies
- Quantum Dots Synthesis And Properties
- Extracellular vesicles in disease
- Advancements in Battery Materials
- Bone and Dental Protein Studies
Wuhan Polytechnic University
2013-2024
Royal Society of Chemistry
2024
Centre National pour la Recherche Scientifique et Technique (CNRST)
2024
Huazhong University of Science and Technology
2014-2018
Battery Park
2016
China University of Geosciences
2016
Collagen has shown promising potential in biomedical fields due to its high biocompatibility, abundance of resources, ease flexible modification, and for active targeting. The capacity is largely influenced by their unique structure properties. typically extracted from tissues organs that are commonly discarded as waste. extraction collagen agricultural sideline resources an environmentally friendly method utilizing byproducts generating high-value products. methods can significantly impact...
Differences between CDs prepared by microwave reaction and conventional hydrothermal methods were systematically compared to guide the optimization of parameters biomass-derived CDs.
The uncontrollable migration of cancer cells is one the reasons for poor prognosis. interaction between collagen and cellular processes usually dominated by full triple‐helix structure collagen. However, it remains to be explored how configuration affects behaviors cells. Michigan foundation‐7 are chosen study this relationship. Meanwhile, grass carp representative fish species in Hubei virtually unaffected zoonotic diseases. Therefore, carp‐derived prepared used modulate behaviors. sample...
Stem cells serve as promising candidates for regenerative medicine. The migration capability of stem may determine the treatment efficacy. Currently, chemotaxis and thigmotaxis are two plausible approaches to regulate...
Chirality is one of the fundamental biochemical properties in a living system, and lot biological physiological processes are greatly influenced by chirality molecules. Inspired this phenomenon, we study covalent assembly DNA on chiral molecule modified surfaces further discuss hybridization with nucleic acids. Take methylene blue (MB) as model molecule, show that peak current L-NIBC (NIBC, N-isobutyryl-L(D)-cysteine) gold surface (L-surface) larger than D-surface because stronger...
Recently, the incorporation of biomolecules in Metal-organic frameworks (MOFs) attracts many attentions because controlling functions, properties and stability trapped molecules. Although there are few reports on protein/MOFs composites their applications, none DNA/MOFs composite is reported, as far we know. Here, report a new material which self-assembled from 3D DNA (guest) pre-synthesized MOFs (host) by electrostatic interactions hydrophilic well-dispersed fashion. Its biophysical...
Almost all of the important functions DNA are realized by proteins which interact with specific DNA, actually happens in a limited space. However, most studies about protein–DNA binding an unconfined Here, we propose new method, nanopore-based DNA-probe sequence-evolution (NDPSE), includes up to 6 different systems successively designed nanoscale confined space unveil more realistic characteristics phenomena. There several features; for example, first, edge-hindrance and core-hindrance...
The "Plug and Play" template can be individually or successively grafted by dual-responsive molecules on the α-CD modified channels host–guest interactions peeled off UV irradiation. artificial present six kinds of responses cycling among four states responding to three environment stimuli, as light, pH, temperature. As a service our authors readers, this journal provides supporting information supplied authors. Such materials are peer reviewed may re-organized for online delivery, but not...
Xenogeneic collagen coassembly (XCCA) offers a new view for the design and performance regulation of novel collagen-based biomaterials. But there is still lack accurate sensitive method monitoring XCCA. In this study, simple efficient graphene-oxide (GO)-based fluorescence resonance energy transfer (FRET) platform has been developed to sense We first designed fluorescein isothiocyanate (FITC)-labeled porcine skin (PSC) that adsorbed on GO surface effectively quenched its fluorescence. Upon...
Although extensively used in all fields of chemistry, molecular recognition still suffers from a significant limitation: host-guest binding displays fixed, hyperbolic dose-response curve, which limits its usefulness many applications. Here we take advantage the high programmability DNA chemistry and propose universal strategy to engineer biorecognition-based sensors with dual programmable dynamic ranges. Using aptamers as our model element electrochemistry readout signal, first designed...
Nanopore ionic current measurement is currently a prevailing readout and offers considerable opportunities for bioassays. Extending conventional electrochemistry to nanoscale space, albeit noteworthy, remains challenging. Here, we report versatile array established on nanofluidic platform by controllably depositing gold layers the two outer sides of anodic aluminum oxide (AAO) nanopores, leading form an electrochemical microdevice capable performing amperometry in label-free manner....
Abstract The limitations of native collagen, such as thermal stability and solubility in physiological environments, can be improved by applying bioconjugation synthetic chemistry techniques. However, the exquisite control modification site collagen remains a challenge. In this work, pH-responsive poly(acrylic acid) (PAA) with different chain lengths was attached to N-terminal α-amino groups succinylated using site-specific strategy. Additionally, structure, stability, pH sensitivity were...
Systematic analysis of the differential impact collagen structural changes on its binding efficiency with cancer cells and normal cells.