A5033554205- Ovarian function and disorders
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Gynecological conditions and treatments
- Pregnancy and preeclampsia studies
- Prenatal Screening and Diagnostics
- Birth, Development, and Health
- Sperm and Testicular Function
- Ovarian cancer diagnosis and treatment
- Sexual Differentiation and Disorders
- Lipid metabolism and disorders
- Uterine Myomas and Treatments
- Preterm Birth and Chorioamnionitis
- Healthcare and Venom Research
- Estrogen and related hormone effects
- Pregnancy and Medication Impact
- Plant Molecular Biology Research
- Homicide, Infanticide, and Child Abuse
- Gestational Trophoblastic Disease Studies
- Cancer Mechanisms and Therapy
- Urinary Bladder and Prostate Research
Wuhan University
2013-2023
Renmin Hospital of Wuhan University
2013-2023
Shanghai Jiao Tong University
2015
Intrauterine administration of autologous peripheral blood mononuclear cells (PBMCs) activated by HCG in vitro is reported to improve implantation rates patients with repeated failure IVF-ET. In this article, the impact intrauterine PBMCs on embryo implantation, pregnancy rate and underlying mechanisms will be investigated.Pregnant mice were randomly divided into three groups, including control group; dysfunction (EID) EID group. Uterine horns excised determine number pregnant sites Day 7.5...
We undertook this retrospective variables-control analysis to compare the reproductive outcomes of frozen-thawed embryo transfer using endometrial preparation with either natural cycle or hormone replacement therapy cycle. Patients were divided into three subgroups. Subgroup A (n = 32) consisted patients having 8-cell post-thawed embryos transferred. B 404) good quality C 578) two all intact and mitosis resumption Implantation rate, biochemical pregnancy clinical rate measured. In subgroup...
Problem Many researchers have demonstrated that the expression of interleukin‐17( IL ‐17) is higher in spontaneous abortion. However, whether Th17 cells are an independent factor inducing abortion not known. Method study This investigated effect exogenous recombinant ‐17 and anti‐ antibody a normal mouse model using flow cytometry, enzyme‐linked immunosorbent assay, real‐time PCR , Western blot. Results related factors, ROR γt, were significantly upregulated mice, Treg factor, Foxp3,...
Abstract Background Previous studies showed that thyroid dysfunction in women with gestational hypertension could negatively affect maternal and fetal outcomes. In this study, we aimed to investigate whether assessed the second half trimester contributed neonatal outcomes of pregnancy different subtypes disease. Methods We performed a retrospective case-control study collected data from 135 singleton pregnant disease their offspring who delivered Renmin Hospital Wuhan University January 2015...
Abstract In this study, we explored the optimal treatment for cesarean scar pregnancy (CSP). One hundred three women diagnosed with CSP received 1 of 3 treatments: local or systemic methotrexate (MTX) injection and surgery (MTX + Surg), uterine arterial embolization (UAE) (UAE Surg) only (Surg only). We compared their therapeutic effects follow-up results. There was no significant difference between groups in baseline clinical characteristic except initial β human chorionic gonadotropin...
In this paper, a retrospective cohort study was conducted to the high ovarian responders in GnRH-antagonist protocols of IVF/ICSI cycles. The purpose is investigate whether dual triggering final oocyte maturation with combination gonadotropin-releasing hormone (GnRH) agonist and human chorionic gonadotropin (HCG) can improve clinical outcome compared traditional dose (10000IU) HCG trigger low-dose (8000IU) for vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) Our included 226...
Embryo implantation is a highly synchronized bioprocess between an activated blastocyst and receptive uterus. In mice, successful relies on the dynamic interplay of estrogen progesterone; however, key mediators downstream these hormones that act competency endometrium receptivity acquisition are largely unknown. this study, we showed expression osteopontin (OPN) in mouse blastocysts regulated by ovarian uterine micro-environment. OPN mRNA up-regulated day 4 pregnancy, which associated with...
Spontaneous ovarian hyperstimulation syndrome (sOHSS) is extremely rare. It can be divided into four types according to its clinical manifestations and follicle stimulating hormone receptor mutations.Here we report two cases of sOHSS in Chinese women, one with a singleton gestation developing the first trimester who conceived naturally other twin pregnancy second after thawed embryo transfer cycle. Both patients were admitted hospital abdominal distension, ascites, enlarged ovaries....
The aim of this study was to assess fertility outcome and obstetrical prognosis 46 patients after hysteroscopic section uterine septa with neodysmium:yttrium-aluminum-garnet (Nd:YAG) laser.Approximately 15-25% spontaneous miscarriages are related Müllerian fusion defects, most which associated septa. Operative hysteroscopy is a safe effective treatment for septa.Forty-six sterile septate uterus received metroplasty Nd:YAG laser. Forty-one incomplete were under the guidance B-ultrasonography,...
Problem To examine the immunocontraceptive properties of plasmid pcDNA ‐ mCRISP 1 and compare them to corresponding recombinant ( r‐mCRISP 1). Method study RT‐PCR indirect immunofluorescence were performed observe protein expression in COS ‐7 cells. Three groups mice received three injections 1, or vector, respectively. ELISA Western blot used immune responses immunoreactivity antisera. Sperm‐egg penetration assay was effect anti‐ antibodies vitro fertilization mouse oocytes. Fertility mean...