Lin Chen

ORCID: 0000-0002-7767-1772
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About
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Research Areas
  • Stochastic processes and financial applications
  • Metal Extraction and Bioleaching
  • Differential Equations and Numerical Methods
  • Extraction and Separation Processes
  • Economic theories and models
  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Market Dynamics and Volatility
  • Iron and Steelmaking Processes
  • Metallurgical Processes and Thermodynamics
  • Advanced Mathematical Modeling in Engineering
  • Complex Systems and Time Series Analysis
  • Parasites and Host Interactions
  • Insurance, Mortality, Demography, Risk Management
  • Numerical methods for differential equations
  • Nanoparticle-Based Drug Delivery
  • Pancreatic and Hepatic Oncology Research
  • Caching and Content Delivery
  • Internet Traffic Analysis and Secure E-voting
  • Monetary Policy and Economic Impact
  • Energy, Environment, Economic Growth
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Mobile Ad Hoc Networks
  • Advanced Nanomaterials in Catalysis

Huazhong University of Science and Technology
2009-2024

Central South University
2015-2024

Corden Pharma (United States)
2024

Jiangxi University of Finance and Economics
2015-2024

Tongji Hospital
2015-2024

University of Nottingham Ningbo China
2023-2024

Jiaxing University
2024

Columbia University
2024

Sun Yat-sen University
2021-2023

North China University of Water Resources and Electric Power
2023

Sodium layered oxides are considered to be cathode candidates with the most potential for large-scale energy storage because of their high reversible capacity and wide availability sodium resources. A significant hurdle application these lies in simultaneously satisfying high-energy density long cycle life intrinsic problems associated structural irreversibility. Herein, a O3/O'3-P2 core-shell composite that integrates specific from O-type Ni-based core good stability P2-type Mn-rich shell...

10.1021/acsami.9b19260 article EN ACS Applied Materials & Interfaces 2020-01-21

The use of chloroquine treatment for Plasmodium falciparum malaria was abandoned in China 1979 because widespread drug resistance. Subsequent studies found decreases the prevalence chloroquine-resistant strains. To evaluate these and assess current status sensitivity Hainan, China, we determined P. resistance transporter (PfCRT) 76T marker DNA blood samples collected from 1978 to 2001. Results showed presence PfCRT 101 112 (90%) 1981, 30 43 (70%) 1986, 22 34 (65%) 1997 1998, 37 68 (54%) thus...

10.4269/ajtmh.2005.72.410 article EN American Journal of Tropical Medicine and Hygiene 2005-04-01

ABSTRACT Understanding protective immunity to malaria is essential for the design of an effective vaccine prevent large number infections and deaths caused by this parasitic disease. To date, whole-parasite immunization with attenuated parasites most method confer sterile protection against infection in clinical trials. Mouse model studies have highlighted role that CD8 + T cells play preerythrocytic stages malaria; however, there mounting evidence antibodies are also important these stages....

10.1128/iai.02320-14 article EN Infection and Immunity 2014-09-30

Static loading tests were conducted on 16 steel–concrete composite beams and two steel to investigate shear resisting mechanisms the strength of beams. The main experimental parameters span aspect ratio simply supported beams, width thickness concrete flanges. Based strain measurements, stress in beam was analyzed using theories elasticity plasticity, vertical that resisted calculated. resistance flange then obtained by subtracting contribution from total load applied. It found could sustain...

10.1061/(asce)0733-9445(2004)130:8(1206) article EN Journal of Structural Engineering 2004-07-16

China’s bond market is an emerging market. The number of defaults has been increasing in recent years, but the data set severely imbalanced. Based on financial total 6731 corporate issuers which 50 had defaulted, this paper uses XGboost algorithm and Over-sampling method named SMOTE to predict default issuers. results show that advantages over traditional processing imbalanced data, one effective methods deal with samples. Then, way risk

10.4236/tel.2021.112019 article EN Theoretical Economics Letters 2021-01-01

10.1016/j.cam.2021.113482 article EN Journal of Computational and Applied Mathematics 2021-02-15

Pancreatic cancer is the seventh leading cause of death worldwide, which demonstrated with remarkable resistance to radiotherapy and chemotherapy. The identification prognosis signature novel prognostic markers will facilitate patient stratification an individualized precision therapy strategy. In this study, TCGA-PAAD was used screen E3 ubiquitin ligases establish signatures, GEO database verify accuracy signatures. Functional analysis, in vitro experiments clinical cohort studies were...

10.3389/fimmu.2023.1332626 article EN cc-by Frontiers in Immunology 2024-01-18

Named Data Networking (NDN) is recognized as one of the most promising future Internet architectures, employing semantic classification to identify devices, thereby enhancing network usability, scalability, and resilience compared traditional configurations. However, an emergent technology, NDN necessitates further development, particularly in areas like signature privacy data security. This paper primarily addresses detection mitigation cache pollution attacks, a significant issue existing...

10.1016/j.iot.2024.101142 article EN cc-by Internet of Things 2024-02-29

Background Hepatitis B and schistosomiasis are most prevalent in Africa Asia, co-infections of both frequent these areas. The immunomodulation reported to be induced by schistosome infections might restrict immune control hepatitis virus (HBV) leading more severe viral infection. Vaccination is the effective measure prevent HBV infection, but there evidence for a reduced response vaccine patients with chronic japonica. Methodology/Principal Findings In this paper, we demonstrate mouse model...

10.1371/journal.pone.0051512 article EN cc-by PLoS ONE 2012-12-14

The Epstein-Barr virus latent membrane protein 1 (LMP1) is an integral protein. LMP1 has been reported to activate the NF-κB and mitogen-activated kinase pathways. However, these effects alone are unable account for profound oncogenic properties of LMP1. TAZ one nuclear effectors Hippo-related pathways highly expressed in many human tumors. Here, we that was frequently LMP1-positive nasopharyngeal carcinoma. In NPC cell lines, showed promoted expression. Gelsolin important inhibitor...

10.18632/oncotarget.13775 article EN Oncotarget 2016-12-02
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