A5074515229- Stress Responses and Cortisol
- Renin-Angiotensin System Studies
- Tryptophan and brain disorders
- Renal function and acid-base balance
- Protease and Inhibitor Mechanisms
- Pain Management and Opioid Use
- Nanoparticles: synthesis and applications
- Vitamin C and Antioxidants Research
- Adenosine and Purinergic Signaling
- Neuropeptides and Animal Physiology
- Occupational Health and Burnout
- Alcohol Consumption and Health Effects
- Nicotinic Acetylcholine Receptors Study
- Neuroendocrine regulation and behavior
- Diet, Metabolism, and Disease
- Opioid Use Disorder Treatment
- Acute Kidney Injury Research
- Pain Mechanisms and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Apelin-related biomedical research
- COVID-19 and Mental Health
- Free Radicals and Antioxidants
- Curcumin's Biomedical Applications
- Healthcare during COVID-19 Pandemic
- Biochemical Analysis and Sensing Techniques
Universidade Federal de Alfenas
2020-2025
University of Limerick
2023
Mental disorders affect the population widely, and university students are considered a risk group due to challenges of academic life. Furthermore, COVID-19 pandemic has had major impact on this population, intensifying symptoms anxiety depression. On other hand, there is high consumption psychoactive substances among academics, which initially aim minimize internal tensions, but can, in chronic manner, harm health. Given this, quantitative, descriptive, cross-sectional study was carried out...
ABSTRACT In the present study, we investigated whether curcumin administration would interfere with main renal features of l ‐NAME‐induced hypertension model. For this purpose, conducted both in vitro and vivo experiments to evaluate indicators inflammation, oxidative stress, metalloproteinases (MMPs) expression/activity. Hypertension was induced by ‐NAME (70 mg/kg/day), Wistar rats from control hypertensive groups were treated (50 or 100 mg/kg/day; gavage) vehicle for 14 days. Blood kidneys...
Several clinical and experimental studies have documented a compelling critical role for the full-length matrix metalloproteinase-2 (FL-MMP-2) in ischemic renal injury, progressive fibrosis, diabetic nephropathy. A novel N-terminal truncated isoform of MMP-2 (NTT-MMP-2) was recently discovered, which is induced by hypoxia oxidative stress activation latent promoter located first intron MMP2 gene. This NTT-MMP-2 enzymatically active but remains intracellular or near mitochondria. In this...
AbstractThe association between death from Covid-19 and case management, especially in small medium-sized municipalities, is still uncertain. To analyze sociodemographic, clinical, pharmacological factors associated with patients Coronavirus Disease 2019 (COVID-19), a Brazilian referral public hospital. This cross-sectional study, data the hospital records of (≥ 18 years old) diagnosed COVID-19, March 2020 to 2021. The sample was classified according clinical outcome into two groups (death...
Chronic ethanol consumption and sepsis cause oxidative stress renal dysfunction. This study aimed to examine whether chronic sensitizes the mouse kidney sub-lethal cecal ligation puncture (SL-CLP) sepsis, leading impairment of function by tissue inflammatory damage. Male C57BL/6J mice were treated for 9 weeks with (20%, v/v) before SL-CLP was induced. Systolic blood pressure (SBP), survival rate, creatinine plasma, stress, parameters, inducible nitric oxide synthase (iNOS), cytokines,...
Nicotine has been used during pregnancy and lactation as a tobacco harm reduction strategy. However, it is unclear whether nicotine exposure critical development period negatively impacts stress responses in adulthood. This study investigated how nicotine, administered via breastfeeding, affects the brain-derived neurotrophic factor (BDNF), synaptic proteins levels, anxiety-like behavior adult female mice subjected to stress. Female Swiss were exposed saline or (8 mg/kg/day) through...