Sílvia Graciela Ruginsk

ORCID: 0000-0002-0534-0077
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About
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Research Areas
  • Neuroendocrine regulation and behavior
  • Stress Responses and Cortisol
  • Neuroscience of respiration and sleep
  • Regulation of Appetite and Obesity
  • Sleep and Wakefulness Research
  • Renin-Angiotensin System Studies
  • Electrolyte and hormonal disorders
  • Cannabis and Cannabinoid Research
  • Musculoskeletal pain and rehabilitation
  • Birth, Development, and Health
  • Circadian rhythm and melatonin
  • Nitric Oxide and Endothelin Effects
  • Myofascial pain diagnosis and treatment
  • Neuropeptides and Animal Physiology
  • Dietary Effects on Health
  • Acupuncture Treatment Research Studies
  • Pancreatic function and diabetes
  • Biochemical Analysis and Sensing Techniques
  • Nerve Injury and Rehabilitation
  • Medical research and treatments
  • Heart Rate Variability and Autonomic Control
  • Healthcare during COVID-19 Pandemic
  • Occupational Health and Burnout
  • Tryptophan and brain disorders
  • Sulfur Compounds in Biology

Universidade Federal de Alfenas
2015-2025

Universitario Francisco de Asís
2021-2025

Universidade de São Paulo
2003-2019

Universidade de Ribeirão Preto
2003-2014

Universidade Brasil
2009-2013

To evaluate the effects of auricular acupuncture on pain intensity, its impact daily activities, relief provided by intervention, and threshold in people with back musculoskeletal disorders.Randomized clinical trial carried out randomly allocated into three groups: treatment, placebo, control. Evaluations were performed using Brief Pain Inventory a digital algometer before (initial) after (final) treatment 15-day follow-up period.The sample was 110 people. There decrease intensity placebo...

10.1590/s1980-220x2018009003418 article EN cc-by Revista da Escola de Enfermagem da USP 2019-01-01

Fluid volume and osmolality balance are maintained by complex neuroendocrine liquid-salt intake behavior, cardiovascular renal mechanisms, gastrointestinal adjustments. Mechanical stretching of the right atrium (AS) enhances central venous pressure heart rate while decreasing gastric emptying (GE) liquid in rats. We evaluated effect AS on GE plasma levels atrial natriuretic peptide (ANP), oxytocin (OT), corticosterone (CORT) to determine whether ANP contributes OT-mediated delay liquids due...

10.1152/ajpregu.00172.2024 article EN AJP Regulatory Integrative and Comparative Physiology 2025-02-12

Important inputs originating in the forebrain circumventricular organs and also central amygdala (CeA) trigger essential water deprivation (WD)-induced behaviors, such as thirst sodium appetite. Together with secretion of neurohypophysial peptides vasopressin (AVP) oxytocin (OT), these behavioral responses seek to maintain normalcy ECF osmolality volume. Within this context, main hypothesis tested by present study was that CeA type 1 cannabinoid receptors (CB1Rs) were for maintenance body...

10.1152/ajpregu.00241.2024 article EN AJP Regulatory Integrative and Comparative Physiology 2025-02-18

Ethanol (ETOH) consumption has been associated with endocrine and autonomic changes, including the development of hypertension. However, sequence pathophysiological events underlying emergence this effect is poorly understood. Aims: This study aimed to establish a time-course correlation between neuroendocrine cardiovascular changes contributing hypertension following ETOH consumption. Methods: Male adult Wistar rats were subjected intake increasing concentrations in their drinking water...

10.1093/alcalc/agt040 article EN Alcohol and Alcoholism 2013-06-02

to assess the action of ear acupuncture on disability and tissue temperature in people with chronic pain spinal column.a clinical trial a sample 110 people, randomized into three groups: Treatment, Placebo Control. The assessment instruments were Rolland Morris Disability Questionnaire (RMDQ) thermographic camera, administered before first treatment session, one week after 15 days (follow-up) fifth session acupuncture. In analysis data, Kruskal Wallis, Student-Newman Keuls Wilcoxon tests...

10.1590/1518-8345.2678.3050 article EN cc-by Revista Latino-Americana de Enfermagem 2018-09-03

Glucocorticoids have major effects on food intake, demonstrated by the decrease of intake following adrenalectomy. Satiety signals are relayed to nucleus solitary tract (NTS), which has reciprocal projections with arcuate (ARC) and paraventricular (PVN) hypothalamus. We evaluated glucocorticoids activation hypothalamic NTS neurons induced in rats subjected adrenalectomy (ADX) or sham surgery 7 days before experiments. One-half ADX animals received corticosterone (ADX+B) drinking water (B: 25...

10.1152/japplphysiol.90865.2008 article EN Journal of Applied Physiology 2008-11-20

ABSTRACT In the present study, we investigated whether curcumin administration would interfere with main renal features of l ‐NAME‐induced hypertension model. For this purpose, conducted both in vitro and vivo experiments to evaluate indicators inflammation, oxidative stress, metalloproteinases (MMPs) expression/activity. Hypertension was induced by ‐NAME (70 mg/kg/day), Wistar rats from control hypertensive groups were treated (50 or 100 mg/kg/day; gavage) vehicle for 14 days. Blood kidneys...

10.1002/cbf.4119 article EN Cell Biochemistry and Function 2024-09-08

The aim of the present work was to establish a time-course correlation between vascular and autonomic changes that contribute development hypertension during ethanol ingestion in rats. For this, male Wistar rats were subjected intake increasing concentrations their drinking water four weeks. Ethanol effects investigated at end each week. Mild already observed first week treatment, progressive blood pressure increase along evaluation period. Increased pressor response phenylephrine from...

10.1016/j.taap.2014.08.012 article EN publisher-specific-oa Toxicology and Applied Pharmacology 2014-08-20

The endocannabinoid system includes important signaling molecules that are involved in several homeostatic and neuroendocrine functions. In the present study, we evaluated effects of type 1 cannabinoid (CB(1)) receptor antagonist, rimonabant (10 mg/kg, p.o.), on hormone secretion, neuronal activation mRNA expression hypothalamus following isotonic (I-) or hypertonic (H-) extracellular volume expansion (EVE). total nitrate content PVN SON was also assessed under same experimental conditions....

10.1016/j.expneurol.2010.03.001 article EN publisher-specific-oa Experimental Neurology 2010-03-09

(1) The aim of the present study was to evaluate effects intracerebroventricular administration anandamide (AEA), an inhibitor fatty acid amide hydrolase activity (URB597) and a CB1 receptor (CB1 R) antagonist (AM251) on homeostatic responses elicited by extracellular volume expansion (EVE) in male adult rats. (2) Pretreatment with AEA (100 ng/4 μL) significantly reduced effect hypertonic (H-) EVE plasma concentrations prolactin (PRL), oxytocin (OT) corticosterone, but not vasopressin (AVP)....

10.1111/1440-1681.12155 article EN Clinical and Experimental Pharmacology and Physiology 2013-07-23

Abstract Aims and objectives To compare the efficacy of Chinese French ear acupuncture in people with chronic back pain. Background Chronic pain is a common public health problem worldwide. An intervention for this condition acupuncture. Several approaches are used acupuncture, particularly guidelines. Methods open, randomised controlled clinical trial, followed recommendations CONSORT Checklist. One hundred eleven were selected into three groups: Control. Evaluations performed before first...

10.1111/jocn.14983 article EN Journal of Clinical Nursing 2019-06-25

Fluoxetine, a serotonin reuptake inhibitor (SSRI), has other effects in addition to blocking reuptake, including changes the vasomotor tone. Whereas many studies focused on acute of fluoxetine vasculature, its chronic are still limited. In present study, we tested hypothesis that treatment modulates adrenergic vascular responses by interfering with post- and pre-synaptic mechanisms. Wistar rats were treated vehicle (water) or (10 mg/kg/day) for 21 days. Blood pressure (BP) heart rate...

10.1016/j.ejphar.2017.02.029 article EN publisher-specific-oa European Journal of Pharmacology 2017-02-17

The present study investigated the type 1 cannabinoid receptor (CB1R) as a potential candidate to mediate homeostatic responses triggered by 24 h of water deprivation, which constitutes primarily hydroelectrolytic challenge and also significantly impacts energy homeostasis. results demonstrated for first time that CB1R mRNA expression is increased in hypothalamus water-deprived (WD) rats. Furthermore, administration ACEA, selective agonist, potentiated WD-induced dipsogenic effect, whereas...

10.1152/ajpregu.00536.2014 article EN AJP Regulatory Integrative and Comparative Physiology 2015-10-15

Abstract Excessive sodium (Na + ) intake in modern society has been associated with several chronic disorders such as hypertension. Several studies suggest that early life events can program physiological systems and lead to functional changes adulthood. Therefore, we investigated behavioral neuroendocrine responses under basal conditions after 48 h of water deprivation adult (60‐day‐old Wistar rats) male, rats originating from dams were offered only or 0.15 mol/L NaCl during pregnancy...

10.14814/phy2.13210 article EN cc-by Physiological Reports 2017-03-01
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