Zhimei Song

ORCID: 0000-0002-7967-6606
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Curcumin's Biomedical Applications
  • Advanced Drug Delivery Systems
  • Advancements in Transdermal Drug Delivery
  • Pharmacological Effects of Natural Compounds
  • Catalytic Processes in Materials Science
  • Nanocomposite Films for Food Packaging
  • Natural product bioactivities and synthesis
  • Antimicrobial agents and applications
  • Dendrimers and Hyperbranched Polymers
  • Chemical Synthesis and Analysis
  • Magnolia and Illicium research
  • Surfactants and Colloidal Systems
  • Drug Solubulity and Delivery Systems
  • Nanomaterials for catalytic reactions
  • Nail Diseases and Treatments
  • Nanoplatforms for cancer theranostics
  • Essential Oils and Antimicrobial Activity
  • Chemical Synthesis and Reactions
  • Phytochemistry and biological activity of medicinal plants
  • Polyoxometalates: Synthesis and Applications
  • Polymer Nanocomposites and Properties
  • Antifungal resistance and susceptibility
  • Mesoporous Materials and Catalysis
  • Zeolite Catalysis and Synthesis

University of Jinan
2015-2024

Liaoning Normal University
2024

Shenyang Institute of Automation
2022

John Wiley & Sons (United States)
2020

Smith College
2020

Syracuse University
2020

University of Rochester
2020

Shandong First Medical University
2013

Chengdu Women's and Children's Central Hospital
2011

Shandong University
2009-2010

Background: Curcumin (CUR) has been linked with antioxidant, anti-inflammatory, antimicrobial, anti amyloid, and antitumor effects, but its application is limited because of low aqueous solubility poor oral bioavailability. Methods: To improve bioavailability water solubility, we synthesized two series poly (ε-Caprolactone)-poly (ethylene glycol)-poly (ε-Caprolactone) triblock copolymers by ring-opening polymerization glycol) ε-Caprolactone, stannous 2-ethylhexanoate as the catalyst....

10.2147/ijn.s33607 article EN cc-by-nc International Journal of Nanomedicine 2012-07-01

10.1016/j.ijpharm.2014.05.059 article EN International Journal of Pharmaceutics 2014-06-02

Abstract To expand the market capacity of p ‐diethylbenzene (PDEB), core‐shell zeolite (TS‐1@MCM‐48) is designed as a catalyst for PDEB oxidation. TS‐1@MCM‐48 synthesized by in‐situ crystallization method and characterized X‐ray diffraction (XRD), transmission electron microscope (TEM), scanning (SEM), photoelectron spectroscopy (XPS), N 2 adsorption‐desorption, paramagnetic resonance (EPR) 29 Si nuclear magnetic ( MAS‐NMR). Oxidation H O was investigated systematically in liquid phase. The...

10.1002/chem.202303739 article EN Chemistry - A European Journal 2024-01-30

Inflammation and excessive reactive oxygen species production are the main reason for slow wound healing, which necessitates an efficient therapy in clinic.

10.1039/d1nj04719a article EN New Journal of Chemistry 2022-01-01

Purpose: To improve curcumin’s pharmacokinetic, in vitro cytotoxicity and release property.Methods: A novel linear-dendrimer methoxy-poly (ethylene glycol)-b-poly (ɛ-caprolactone) copolymer was synthesized through O-alkylation, basic hydrolysis ring-opening polymerization reaction with glycol), epichlorohydrin ɛ-caprolactone as raw materials. Its structure characterized by 1H-NMR GPC. The copolymer’s hemolysis micellar encapsulation for curcumin thin-film hydration were studied....

10.3109/10717544.2014.901436 article EN Drug Delivery 2014-04-14

Although curcumin possesses anti-atherogenic and anti-inflammatory properties, its application is limited because of low aqueous solubility poor oral bioavailability. Recently, our group synthesized a novel linear-dendrimer methoxy-poly (ethylene glycol)-b-poly(ε-caprolactone) copolymer nanoparticle loading (Cur-NPs) which could improve release property curcumin. In the present study, we further evaluated anti-atherosclerotic effect in apolipoprotein E −/− mice. Our results demonstrated that...

10.1177/0885328218815328 article EN Journal of Biomaterials Applications 2018-12-12

HPW/β-T+S has the best desulfurization activity among composite catalysts supported by polyoxometalates with different structures.

10.1039/d4nj00214h article EN New Journal of Chemistry 2024-01-01

Ketoconazole is a broad spectrum imidazole antifungal drug. For the treatment of superficial fungal infections with ketoconazole, it needs to be permeated deep skin layers. In order develop topical formulation ketoconazole for improving its deposition and water-solubility, ketoconazole-loaded methoxy poly (ethylene glycol)-b-poly (δ-valerolactone) micelles were developed through thin-film hydration method. Particle size, drug loading capacity, infrared X-ray diffraction drug-loaded...

10.1080/09205063.2016.1244371 article EN Journal of Biomaterials Science Polymer Edition 2016-10-03
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