Ying Guo

ORCID: 0000-0003-4010-355X
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Microbial infections and disease research
  • biodegradable polymer synthesis and properties
  • Polyoxometalates: Synthesis and Applications
  • Aquaculture disease management and microbiota
  • Catalytic Processes in Materials Science
  • Animal Virus Infections Studies
  • Reproductive Biology and Fertility
  • Chemical Synthesis and Reactions
  • Pharmacological Effects of Natural Compounds
  • Catalysis for Biomass Conversion
  • Venous Thromboembolism Diagnosis and Management
  • Stroke Rehabilitation and Recovery
  • RNA modifications and cancer
  • Plant-based Medicinal Research
  • Traditional Chinese Medicine Analysis
  • Neurological Disease Mechanisms and Treatments
  • Adipose Tissue and Metabolism
  • Cardiac Health and Mental Health
  • Flavonoids in Medical Research
  • Gestational Diabetes Research and Management
  • Prenatal Screening and Diagnostics
  • Endometriosis Research and Treatment
  • Zeolite Catalysis and Synthesis
  • Ovarian function and disorders

Zhejiang Chinese Medical University
2009-2025

Hangzhou First People's Hospital
2025

Zhejiang University
2011-2025

Shenyang Agricultural University
2012-2024

Tianjin University of Traditional Chinese Medicine
2013-2024

Liaoning Normal University
2021-2024

International Peace Maternity & Child Health Hospital
2024

Shanghai Jiao Tong University
2015-2024

First Affiliated Hospital of Xi'an Jiaotong University
2023-2024

Puer University
2024

BACKGROUND: Whether it is effective and safe to extend the time window of intravenous thrombolysis up 24 hours after last known well unknown. We aimed determine efficacy safety tenecteplase in Chinese patients with acute ischemic stroke due large/medium vessel occlusion within an extended window. METHODS: Patients presenting 4.5 from well, a favorable penumbral profile associated occlusion, were randomized 1:1 either 0.25 mg/kg or best medical treatment. A was defined as hypoperfusion lesion...

10.1161/strokeaha.124.048375 article EN Stroke 2025-01-02

A highly efficient catalyst for the simultaneous catalytic oxidation of bulky and small-molecule sulfides was designed in this work.

10.1039/d3nj01058a article EN New Journal of Chemistry 2023-01-01

Abstract To expand the market capacity of p ‐diethylbenzene (PDEB), core‐shell zeolite (TS‐1@MCM‐48) is designed as a catalyst for PDEB oxidation. TS‐1@MCM‐48 synthesized by in‐situ crystallization method and characterized X‐ray diffraction (XRD), transmission electron microscope (TEM), scanning (SEM), photoelectron spectroscopy (XPS), N 2 adsorption‐desorption, paramagnetic resonance (EPR) 29 Si nuclear magnetic ( MAS‐NMR). Oxidation H O was investigated systematically in liquid phase. The...

10.1002/chem.202303739 article EN Chemistry - A European Journal 2024-01-30

Background The performance of intravenous tenecteplase in patients who had an acute ischaemic stroke with large/medium vessel occlusion or severe stenosis extended time window remains unknown. We investigated the promise efficacy and safety different doses manufactured China, beyond 4.5-hour window. Methods CHinese Acute tissue-Based imaging selection for Lysis In Stroke-Tenecteplase was investigator-initiated, umbrella phase IIa, open-label, blinded-endpoint, Simon’s two-stage randomised...

10.1136/svn-2023-002820 article EN cc-by-nc Stroke and Vascular Neurology 2024-01-29

The fluorolytic sol–gel route sets a milestone in the development of synthesis methods for nanoscopic fluoride materials. They exhibit fundamentally distinct properties comparison to classically prepared metal fluorides. To broaden this area, we report paper first ZnF2. obtained sol was studied with dynamic light scattering (DLS). dried ZnF2 xerogel investigated elemental analysis, thermal powder X-ray diffraction (XRD), solid-state MAS NMR, and N2 adsorption–desorption measurements....

10.1039/c2jm31357j article EN Journal of Materials Chemistry 2012-01-01

Summary Introduction Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in reproductive‐age women. Irisin considered to play a role metabolic disorder and PCOS . However, correlation between irisin not clear. Material methods This prospective study. Forty patients with thirty without were recruited for vitro fertilization embryo transfer ( IVF ‐ ET ). All women fulfilled all three Rotterdam consensus criteria. In each group, also divided into obese nonobese patients, or...

10.1111/cen.13805 article EN Clinical Endocrinology 2018-07-04
Sohei Yoshimura Richard I. Lindley Cheryl Carcel Shoichiro Sato Candice Delcourt and 95 more Xia Wang John Chalmers Craig S. Anderson Hisatomi Arima Yining Huang Jong Sung Kim Pablo M. Lavados Tsong‐Hai Lee Christopher Levi Mark Parsons Sheila Cristina Ouriques Martins Jeyaraj Pandian Octávio Marques Pontes‐Neto Thompson Robinson Vijay K. Sharma Nguyen Huy Thang Christian Stapf Ji‐Guang Wang Joanna M. Wardlaw Philip M. Bath Joseph P. Broderick Andrew M. Demchuk Geoffrey A. Donnan Laurent Billot Qiang Li MBiostat Mark Woodward P. J. Gordon Sully Xiomara Fuentes Patarroyo Dino Benito Hossein Zareie Yongjun Cao Amy Kunchok Stephen L. Winters Shelagh B. Coutts Tom J. Moullaali Yongjun Cao Jie Yang Guojun Wu Shihong Zhang Lili Song Guofang Chen Lisa Manning Amit Mistri Victoria J. Haunton Xiaoying Chen Joyce Lim Sharon Tucker Leibo Liu Sully Xiomara Fuentes Patarroyo Penelope Gordon Sarah Richtering Xia Wang Kerry Jenson Elizabeth Knight Elizaveta Ivanova Emma Thembani E. Odgers Elizabeth A. Sanders Sabrina Small Ruchita Vaghasiya Manuela Armenis Paul S. Donnelly Merza Ahmad Baig N. J. Blacklock B. Naidu Ravinder Singh Zhen Xi Hua Deng Buliang Cui Ying Guo L He Ruolan Jia Nan Li Wei Li Mengxiao Liu Ziwei Xu Meng Zhang Ting Zhang Yan Zhao Yunjeong In Su Kim Jung Eun Ahn Sul Hwa Kim Young Lan Hong Verónica V. Olavarría Francisca González Bernardita Portales Alejandra Malavera Magda Carla Ouriques Martins Taiwan Ching‐Yi Wang S J Ryu Alice Durham Hardeep Aujla Sue Lewin Tracy Kumar Vietnam

To determine the optimal cut point on NIH Stroke Scale (NIHSS) for predicting poor 90-day clinical outcome in patients with supratentorial and infratentorial acute ischemic stroke (AIS).Data are from participants of alteplase-dose arm randomized controlled trial, Enhanced Control Hypertension Thrombolysis Study (ENCHANTED). Associations between baseline characteristics clinically defined AIS functional outcome, by scores 3-6 modified Rankin Scale, were evaluated logistic regression models,...

10.1212/wnl.0000000000006437 article EN Neurology 2018-09-29
Ying Xu Maree L. Hackett John Chalmers Richard I. Lindley Xia Wang and 95 more Qiang Li Thompson Robinson Hisatomi Arima Pablo M. Lavados Craig S. Anderson John Chalmers Craig S. Anderson Richard I. Lindley Hisatomi Arima Yining Huang Jong Sung Kim Pablo M. Lavados Tsong‐Hai Lee Christopher Levi Mark Parsons Sheila Cristina Ouriques Martins Jeyaraj Pandian Octávio Marques Pontes‐Neto Thompson Robinson Vijay K. Sharma Nguyen Huy Thang Shoichiro Sato Christian Stapf Ji-Guang Wang Joanna M. Wardlaw Philip M. Bath Joseph P. Broderick Andrew M. Demchuk Geoffrey A. Donnan R. J. Simes Graeme J. Hankey Peter Sandercock Marie‐Germaine Bousser Ka Sing Wong Laurent Billot Qiang Li Anish Scaria Xia Wang Yoichiro Hirakawa Mark Woodward Richard I. Lindley Candice Delcourt Cheryl Carcel P. J. Gordon Sully Xiomara Fuentes Patarroyo Dino Benito Christopher Levi Mark Parsons Hossein Zareie Yongjun Cao Amy Kunchok Stephen L. Winters Shelagh B. Coutts Cheryl Carcel Tom J. Moullaali Yongjun Cao Jie Yang Guojun Wu Shihong Zhang Lili Song Guofang Chen Thompson Robinson Lisa Manning Xiaoying Chen Joyce Lim Sharon Tucker Leibo Liu Sully Xiomara Fuentes Patarroyo Penelope Gordon Sarah Richtering Xia Wang Kerry Jenson Elizabeth Knight Elizaveta Ivanova Emma Thembani E. Odgers Elizabeth A. Sanders Sabrina Small Ruchita Vaghasiya Manuela Armenis Paul S. Donnelly Merza Ahmad Baig N. J. Blacklock B. Naidu Ravinder Singh Helen Monaghan Phillipa Smith Parisa Glass Zhen Xi Hua Deng Buliang Cui Ying Guo L He Ruolan Jia Nan Li

Seizures after ischemic stroke have not been well-studied. We aim to determine the frequency, determinants, and significance of early seizures thrombolysis for acute stroke.Data are from Enhanced Control Hypertension Thrombolysis Stroke Study (ENCHANTED), an international, multicenter, randomized controlled trial where patients with were low-dose (0.6 mg/kg) or standard-dose (0.9 IV alteplase. The protocol prespecified prospective data collection on in-hospital over 7 days postrandomization....

10.1212/cpj.0000000000000384 article EN Neurology Clinical Practice 2017-08-01

Gestational Diabetes Mellitus (GDM) has brought great harm to maternal and fetus. Up now, only a few plasma biomarkers for its early diagnosis have been reported; nevertheless, there is no report about identification of urinary prediction GDM. Thus, it necessary correct this deficiency. In our study, urine samples were collected from 889 healthy young gravidae at the second trimester (15 20 weeks), 69 whom subsequently diagnosed with GDM 24 28 weeks. iTRAQ (the isobaric tags relative...

10.1507/endocrj.ej17-0471 article EN Endocrine Journal 2018-01-01

Abstract Poly(butylene succinate) (PBS) with different ratios of modified talc was prepared by twin-screw extruding. The effect loading amounts on the mechanical, thermal, and crystallization properties PBS investigated. mechanical test results indicate that stiffness composites increased linearly increasing content, tensile strength elongation stayed at relatively high levels when amount is <15 phr. Thermal gravimetric analysis showed thermal stability improved notably a small (5–10 phr)...

10.1515/polyeng-2013-0229 article EN Journal of Polymer Engineering 2014-02-20

Oroxylin A, a natural flavonoid, is one of the main bioactive compounds that underlie anti-inflammatory effect medicinal herb Scutellaria baicalensis Georgi widely used in southeastern Asia; however, molecular mechanisms for therapeutic benefits remain largely unclear. In this study, we found A induces estrogen-responsive gene expression and promoter activity. macrophages, treatment significantly attenuates lipopolysaccharide (LPS)-induced but not basal inflammatory response, including...

10.1371/journal.pone.0069555 article EN cc-by PLoS ONE 2013-07-29

Vaginal microecology has a definite influence on human papillomavirus (HPV) infection and clearance, but the specific correlation is still controversial. This research aimed to investigate differences in vaginal microenvironment of different types HPV also provide data supporting clinical diagnosis treatment.According strict inclusion exclusion criteria, case 2,358 female patients who underwent HPV-DNA tests at same time Department Obstetrics Gynecology First Affiliated Hospital Xi'an...

10.3389/fmed.2023.1138507 article EN cc-by Frontiers in Medicine 2023-06-01

Methyl N-phenyl carbamate (MPC) is an important intermediate for the green synthesis of methylene diphenyl diisocyanate (MDI) as well many other products. In present work, Zn/Al/Ce mixed oxides derived from hydrotalcite-like precursors were employed effective and recoverable heterogeneous catalyst MPC via DMC aminolysis. prepared coprecipitation method resulting catalysts characterized by means XRD, BET, SEM XPS. Strong interactions within observed addition appropriate amount cerium. The...

10.1039/c9ra09642f article EN cc-by-nc RSC Advances 2019-01-01

Objectives: To investigate efficacy of online-offline integrated medical care management in patients with gestational diabetes. Material and methods: A total 140 diabetes were randomly divided into two groups: (IM) group (n = 70) control 70). Patients the treated routine nursing intervention, IM (offline combined WeChat online management). The fasting plasma glucose (FPG), 2h postprandial (2hPG), Self-rating Anxiety Scale (SAS) score, Depression (SDS) Diabetes Care Profile (DPC) 36-item...

10.5603/gp.a2021.0054 article EN cc-by-nc-nd Ginekologia Polska 2021-04-29

An excellent catalyst for hydrodesulfurization, aromatization and olefin hydrogenation of FCC gasoline, is designed in this paper.

10.1039/d1nj02067f article EN New Journal of Chemistry 2021-01-01

Objective: Danggui Buxue decoction (DBD), consisting of Angelicae Sinensis Radix (ASR) and Astragali (AR), is a famous prescription with the function antivasoconstriction. This study intends to probe its mechanisms on relaxation middle cerebral artery (MCA). Methods: Vascular tension rat MCA was measured using DMT620 M system. First, identical series concentrations DBD, ASR, AR were added into resting KCl U46619 preconstricted MCA. According compatibility ratio, their dilatation effects...

10.3389/fphar.2021.749915 article EN cc-by Frontiers in Pharmacology 2021-11-08
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