Huasheng Lai

ORCID: 0000-0002-7985-8290
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About
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Research Areas
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Analytical chemistry methods development
  • Nanocluster Synthesis and Applications
  • Immune cells in cancer
  • Clay minerals and soil interactions
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Intracranial Aneurysms: Treatment and Complications
  • Iron oxide chemistry and applications
  • Advanced Chemical Sensor Technologies
  • Gastric Cancer Management and Outcomes
  • Carbon and Quantum Dots Applications
  • Cancer Diagnosis and Treatment
  • Platelet Disorders and Treatments
  • Tissue Engineering and Regenerative Medicine
  • Infectious Aortic and Vascular Conditions
  • Adsorption and biosorption for pollutant removal
  • Arsenic contamination and mitigation
  • Advanced Drug Delivery Systems
  • Advanced Biosensing Techniques and Applications
  • Esophageal and GI Pathology

Gannan Medical University
2024

South China University of Technology
2022-2024

Guangzhou Medical University
2022-2024

Guangzhou First People's Hospital
2022-2024

Sun Yat-sen University
2020-2023

Chinese University of Hong Kong
2021-2022

Jiangxi Normal University
2018-2019

State Council of the People's Republic of China
2018

A key challenge for the effective treatment of gastrointestinal diseases including inflammatory bowel disease is to develop an orally administered drug delivery system capable prolonged retention in tract. Herein we report a bioadhesive liquid coacervate based on hydrogen bonding-driven nanoparticle assembly. Free from electrostatic interactions, our fluid nanoparticle-assembled demonstrates significant pH- and salt-independent structural stability forms physically adhesive coating large...

10.1038/s41467-021-27463-6 article EN cc-by Nature Communications 2021-12-09

Graphene-based SERS substrates are classified and introduced, their applications in biosensing-related fields reviewed.

10.1039/c8tb00902c article EN Journal of Materials Chemistry B 2018-01-01

Fast and accurate practical sample detection is a great challenge in on-site detection. Herein, we developed CoFe2O4@HNTs/AuNPs substrate for rapid efficient magnetic solid-phase extraction (MSPE) surface-enhanced Raman scattering (SERS) of aromatic amines nitrofuran real samples all-in-one. Magnetic CoFe2O4 beads filled inside halloysite nanotubes (HNTs) can avoid aggregation particles, endow the with separation ability to simplify pretreatment procedure, reduce complex matrix interference....

10.1021/acs.analchem.0c00144 article EN Analytical Chemistry 2020-02-18

Abstract Upper gastrointestinal (GI) hemorrhage is a common clinical emergency worldwide. Endoscopic hemostasis the current first line treatment. Nevertheless, for patients with severe active bleeding and challenging anatomy, endoscopic management can be still difficult usually requires higher level of surgical expertise. A simple effective method therefore in acute demand. Herein hemostatic hybrid hydrogel comprised hyaluronic acid polyethylene glycol stabilized by thiourea–catechol...

10.1002/adfm.202109332 article EN Advanced Functional Materials 2021-12-31

Abstract Background Endoscopic submucosal dissection (ESD) is the current standard treatment for early-stage esophageal neoplasms. However, postoperative stricture after extensive mucosal remains a severe challenge with limited effective treatments available. In this study, we introduced chitosan/gelatin (ChGel) sponge encapsulating adipose mesenchymal stem cells (ADMSCs)-derived exosomes (ChGel MSC−Exo ) prevention of stenosis ESD in porcine model. Results Pigs were randomly assigned into...

10.1186/s12951-024-02429-0 article EN cc-by Journal of Nanobiotechnology 2024-04-01

Complex and tedious sample preparation processes have greatly limited rapid analyses of biological samples. In this work, an all-in-one strategy based on a miniaturized gas membrane separation/oven ring enrichment (GMS/ORE) device was developed for efficient surface enhanced Raman scattering (SERS) trace biomarkers in biofluid This integrating gasification separation, liquid trapping, derivatization SERS activation, coffee-ring could highly promote the efficiency preparation. Meanwhile,...

10.1021/acs.analchem.2c03504 article EN Analytical Chemistry 2022-11-16

An efficient SERS substrate composed of gold nanocone arrays with abundant sharp tips directly grown on 3D porous Ni foam (AuNCA@Ni foam) was developed for sensitive detection aromatic dyes.

10.1039/c8ay00840j article EN Analytical Methods 2018-01-01

Improving the speediness of complex sample analysis has attracted much research interest in analytical science. In this work, an enrichment-sensing all-in-one strategy was presented for rapid surface-enhanced Raman spectroscopy (SERS) purine components by using La(OH)3-Au@AgNPs nanocomposite. Two-dimensional (2D) La(OH)3 nanosheets with nanothickness and accessible active sites not only acted as efficient media enrichment analytes but also provided flat planes intensive decoration Au@AgNPs...

10.1021/acs.analchem.3c03604 article EN Analytical Chemistry 2023-12-04
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