A5069829774- Advanced Drug Delivery Systems
- Infectious Aortic and Vascular Conditions
- Surgical Sutures and Adhesives
- Congenital gastrointestinal and neural anomalies
- Electrospun Nanofibers in Biomedical Applications
- Infant Health and Development
- Gastrointestinal motility and disorders
- Tissue Engineering and Regenerative Medicine
- Platelet Disorders and Treatments
- Pharmacological Effects and Toxicity Studies
- Hemostasis and retained surgical items
City University of Hong Kong
2021
Chinese University of Hong Kong
2020-2021
Bioadhesive hydrogel with ultrafast gelation independent of environmental pH is endoscopically delivered to enhance gastric ulcer healing.
A key challenge for the effective treatment of gastrointestinal diseases including inflammatory bowel disease is to develop an orally administered drug delivery system capable prolonged retention in tract. Herein we report a bioadhesive liquid coacervate based on hydrogen bonding-driven nanoparticle assembly. Free from electrostatic interactions, our fluid nanoparticle-assembled demonstrates significant pH- and salt-independent structural stability forms physically adhesive coating large...
Abstract Upper gastrointestinal (GI) hemorrhage is a common clinical emergency worldwide. Endoscopic hemostasis the current first line treatment. Nevertheless, for patients with severe active bleeding and challenging anatomy, endoscopic management can be still difficult usually requires higher level of surgical expertise. A simple effective method therefore in acute demand. Herein hemostatic hybrid hydrogel comprised hyaluronic acid polyethylene glycol stabilized by thiourea–catechol...
Functional intestinal imaging holds importance for the diagnosis and evaluation of treatment gastrointestinal diseases. Currently, preclinical motility in animal models is performed either invasively with excised intestines or noninvasively under anesthesia, cannot reveal dynamics awake condition. Capitalizing on near-infrared optics a high-absorbing contrast agent, we report Trans-illumination Intestine Projection (TIP) system free-moving mice. After complete evaluation, vivo studies,...