A5008190049- Pleural and Pulmonary Diseases
- Pneumothorax, Barotrauma, Emphysema
- Occupational and environmental lung diseases
- Lung Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Trauma Management and Diagnosis
- COVID-19 and healthcare impacts
- Advances in Oncology and Radiotherapy
- Myasthenia Gravis and Thymoma
- Electrospun Nanofibers in Biomedical Applications
- COVID-19 diagnosis using AI
- Lymphatic Disorders and Treatments
- Medical Imaging and Pathology Studies
- Pericarditis and Cardiac Tamponade
- Dental Implant Techniques and Outcomes
- Infectious Diseases and Tuberculosis
- Periodontal Regeneration and Treatments
Mansoura University
2018-2023
Oxford University Hospitals NHS Trust
2021-2023
Churchill Hospital
2021
University of Oxford
2021
Introduction We present findings from the International Collaborative Effusion database, a European Respiratory Society clinical research collaboration. Nonspecific pleuritis (NSP) is broad term that describes chronic pleural inflammation. Various aetiologies lead to NSP, which poses diagnostic challenge for clinicians. A significant proportion of patients with this finding eventually develop malignant diagnosis. Methods 12 sites across nine countries contributed anonymised data on 187...
Background Chylothorax is an uncommon medical condition for which limited data are available regarding the contemporary aetiology, management and outcomes. The goal of this study was to better define these poorly characterised features. Methods records adult patients diagnosed with chylothorax at 12 centres across Europe, America South Africa from 2009–2021 were retrospectively reviewed. Descriptive inferential statistics performed. Results 77 (median age 69 years, male female ratio 1.5)...
Thoracoscopy is the "gold standard" diagnostic modality for investigation of suspected pleural malignancy. It postulated that meticulous assessment cavity may be adequate to indicate malignancy through macroscopic findings nodules, thickening, and lymphangitis. We attempted critically assess this practice, by precisely defining objective criteria which might differentiate benign from malignant diseases according intrapleural pattern anatomical location, thereby explore predilection...
<h3>Introduction</h3> Indwelling pleural catheters (IPC) provide definitive management of malignant effusion. IPCs offer similar control dyspnoea to talc pleurodesis without hospital admission but require ongoing management. Up 47% patients with IPC undergo auto-pleurodesis facilitating removal. Patient factors leading this are not well understood. <h3>Methods</h3> Retrospective analysis data at a UK tertiary centre between 2019–2021. Procedure reports, radiology, pathology and electronic...
Abstract Introduction Malignant pleural effusion is a frequent problem. Pleurodesis performed to prevent its recurrence. New, effective, and safe sclerosing agents are needed. Aim The aim of this was compare efficacy safety silver nitrate solution 0.5% versus cisplatin in achievement pleurodesis malignant effusion. Patients methods Prospective randomized single-blinded clinical trial at Chest, Clinical Oncology Nuclear Medicine Pathology Departments, Mansoura University, from February 2016...
<b>Background:</b> We present findings from the International Collaborative Effusion (ICE) database, an ERS clinical research collaboration. Non-specific pleuritis (NSP) is a broad term that describes chronic pleural inflammation. Various aetiologies lead to this histological finding and pose diagnostic challenge. A significant proportion of patients with histology eventually develop malignant diagnosis <b>Methods:</b> 12 sites across 9 countries contributed data on 175 patients. Descriptive...
<h3>Introduction</h3> Plasminogen Activator Inhibitor-1 (PAI-1) plays an essential role in the pathogenesis of lung and pleural injury. PAI-1 levels infection have been shown to be significantly elevated compared malignant effusions heart failure. A significant variation was seen protein activity fluid from participants with recruited MIST-2 study. Rabbit models injury demonstrated that, along other pro-inflammatory cytokines, is important contributor impaired fibrin clearance subsequent...
<b>Background:</b> It has been postulated that when the intrapleural tumour burden is high, resultant obliteration of normal mesothelial cell surface pleura results in reduction pleurodesis success rate. <b>Aims:</b> to assess hypothesis associated with higher failure, and type can affect outcomes <b>Methods:</b> Review recorded video footage local anaesthetic thoracoscopy (LAT) procedures 45 patients proven MPE was conducted by 2 independent assessors blinded patient medical records....
<b>Intro:</b> The pandemic has put a strain on healthcare services and resources. Overall procedure capacity was reduced cancer diagnostic pathways were disrupted. procedural urgency associated with symptomatic patients often undiagnosed malignant pleural effusion means that nasopharyngeal PCR testing to exclude COVID-19 prior procedures can be impractical or logistically challenging <b>Aim:</b> To assess two hypotheses; SARS-CoV-2 could not detected in fluid samples from no clinical...