A5100323866- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- CRISPR and Genetic Engineering
- Zoonotic diseases and public health
- Acute Myocardial Infarction Research
- CAR-T cell therapy research
- MicroRNA in disease regulation
- Heat shock proteins research
- Acute Ischemic Stroke Management
- RNA and protein synthesis mechanisms
- Acupuncture Treatment Research Studies
- Pancreatic and Hepatic Oncology Research
- Obstructive Sleep Apnea Research
- Data Stream Mining Techniques
- Gastric Cancer Management and Outcomes
- Inflammatory mediators and NSAID effects
- Plant Gene Expression Analysis
- Diabetic Foot Ulcer Assessment and Management
- Microbial Natural Products and Biosynthesis
- Cardiovascular Health and Disease Prevention
- Wound Healing and Treatments
- Bladder and Urothelial Cancer Treatments
- COVID-19 epidemiological studies
- RNA Interference and Gene Delivery
- ATP Synthase and ATPases Research
Westlake University
2022-2025
Chongqing Medical and Pharmaceutical College
2024
Baylor School
2024
Baylor College of Medicine
2022-2024
Nanjing Agricultural University
2023-2024
Hunan Academy of Traditional Chinese Medicine
2024
Shenzhen Second People's Hospital
2022-2023
Shenzhen University Health Science Center
2022-2023
Xiangya Hospital Central South University
2023
Central South University
2023
Abstract Lignified stone cell content is a key factor used to evaluate fruit quality, influencing the economic value of pear (Pyrus pyrifolia) fruits. However, our understanding regulatory networks formation limited due complex secondary metabolic pathway. In this study, we combination co-expression network analysis, gene expression profiles, and transcriptome analysis in different cultivars with varied identify hub MYB gene, PbrMYB24. The relative PbrMYB24 flesh was significantly correlated...
OsANN1 is a member of the annexin protein family in rice. The function this and mechanisms its involvement stress responses tolerance are largely unknown. Here it reported that confers abiotic by modulating antioxidant accumulation under stress. OsANN1-knockdown [RNA interference (RNAi)] plants were more sensitive to heat drought stresses, whereas OsANN1-overexpression (OE) lines showed improved growth with higher expression Overexpression promoted SOD (superoxide dismutase) CAT (catalase)...
Nav1.7 represents a preeminent target for next-generation analgesics its critical role in pain sensation. Here we report 2.2-Å resolution cryo-EM structure of wild-type (WT) complexed with the β1 and β2 subunits that reveals several previously indiscernible cytosolic segments. Reprocessing data our reported structures Nav1.7(E406K) bound to various toxins identifies two distinct conformations S6IV, one composed α helical turns only other containing π turn middle. The ligand-free...
Pear (Pyrus bretschneideri) fruit stone cells are primarily composed of lignin and have strongly lignified cell walls. The presence has a negative influence on texture taste, thus the reduction content in pear is key goal breeding efforts. However, research into transcription factors regulatory networks associated with formation been limited. We here used combination co-expression network expression quantitative trait locus (eQTL) analyses 206 cultivars different contents to identify...
Background: Integrin β superfamily members (ITGBs) are documented to play important roles in various biological processes, and accumulating evidence suggests that ITGBs associated with carcinogenic effects several malignancies. Gastric cancer (GC) is a complicated highly heterogeneous disease; however, the expression prognostic values of eight potential mechanism GC remain largely unclear. Methods: The significance were systematically analyzed through Gene Expression Profiling Interactive...
The present study aimed to examine whether plasma oxidative stress is associated with cognitive impairment in long term hospitalized patients chronic schizophrenia.Ninety-six schizophrenia and 94 healthy unaffected subjects were enrolled. Plasma markers of stress, including malondialdehyde (MDA), manganese superoxide dismutase (MnSOD), catalase (CAT), glutathione peroxidase (GSH-Px), measured. Psychiatric symptoms function assessed the Positive Negative Syndrome Scale (PANSS) Repeatable...
Acute cerebral ischemic stroke (AIS) dramatically influences patients' quality of life. lncRNA NORAD (NORAD) has been studied in cerebrovascular diseases, which are potential risk factors for AIS. The specific significance is unclear. This study aimed to assess the role AIS, and provide therapeutic value its' treatment.A total 103 AIS patients 95 healthy individuals (control) were enrolled into this study. Expression level plasma all participants was analyzed by PCR. Diagnostic evaluated ROC...
Background: Several studies have suggested that snoring is associated with an increased risk of stroke; however, the results are inconsistent. We aim to conduct a systematic review and meta-analysis observational assessing association between stroke in adults. Methods: searched PubMed for relevant studies. A random-effect model was adopted summary relative risks (RRs), forest plots from cumulative method were used better presentation how pooled RRs changed as updated evidence accumulated....
<b><i>Aims:</i></b> Using specials wearable sensors, we explored changes in gait and balance parameters, over time, elderly patients at high risk of diabetic foot, wearing different types footwear. This assessed the relationship between development foot ulcers, a bid to uncover potential benefits devices prognosis management aforementioned complication. <b><i>Methods:</i></b> A sensor-based monitoring system was used middle-elderly with...
Infectious diseases are a major threat to global health and the economic stability of societies worldwide. To prevent outbreaks, monitoring growth trends infectious appears be particularly important necessary. Herein, data from epidemiological websites, such as World Health Organization National Council used illustrate outbreak for In context COVID-19 pandemic, resurgence in other has been observed, influenza United States. Proper surveillance effective strategies urgently required keep...