A5062391754- COVID-19 Clinical Research Studies
- High Altitude and Hypoxia
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Child Nutrition and Water Access
- Long-Term Effects of COVID-19
- Global Public Health Policies and Epidemiology
- Cystic Fibrosis Research Advances
- Climate Change and Health Impacts
- COVID-19 and Mental Health
- Ethics in Clinical Research
- Ethics in medical practice
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Heme Oxygenase-1 and Carbon Monoxide
- Tracheal and airway disorders
- Neuroscience of respiration and sleep
- Air Quality and Health Impacts
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Inflammasome and immune disorders
- Forensic Entomology and Diptera Studies
- COVID-19 Pandemic Impacts
- Vaccine Coverage and Hesitancy
- Patient Dignity and Privacy
- Public Health and Environmental Issues
- Urban Transport and Accessibility
Pontificia Universidad Católica del Ecuador
2023-2025
Universidad de Las Palmas de Gran Canaria
2023-2025
Universidad Técnica del Norte
2025
Universidad de Las Américas
2019-2024
Universitat de Barcelona
2022
University of the Americas
2021-2022
Liga Contra el Cancer
2021-2022
Escuela Superior Politécnica Agropecuaria de Manabí Manuel Félix López
2022
Institut Pasteur
2020
University of Hong Kong
2020
The SARS-CoV-2 virus has spread rapidly around the globe. Nevertheless, there is limited information describing characteristics and outcomes of COVID-19 patients in Latin America. We conducted a cross-sectional analysis 9,468 confirmed cases reported Ecuador. calculated overall incidence, mortality, case fatality rates, disability adjusted life years, attack crude mortality as well relative risk odds death, for age, sex presence comorbidities. A total positive 474 deaths were included...
Coronaviruses are an extensive family of viruses that can cause disease in both animals and humans. The current classification coronaviruses recognizes 39 species 27 subgenera belong to the Coronaviridae. From those, at least seven known respiratory infections Four these common cold-like symptoms, while others infect evolve become infectious Three recent examples this viral jumps include SARS CoV, MERS-CoV CoV-2 virus. They responsible for causing severe acute syndrome (SARS), Middle East...
Ecuador has been one of the most affected countries by Corona Virus Disease 19 (COVID-19) pandemic, April 2020 this country presented highest rates mortality in Latin America. The purpose present study was to identify behaviors during confinement and sociodemographic variables associated with mental health status confirmed or suspected COVID-19 patients who were part epidemiological surveillance program that included mandatory self-isolation. A cross-sectional performed from March 22th 18th,...
Background Multiple studies have attempted to elucidate the relationship between chronic hypoxia and SARS-CoV-2 infection. It seems that high-altitude is associated with lower COVID-19 related mortality incidence rates; nevertheless, all data came from observational studies, being this first one looking into prospectively collected clinical severely ill patients residing at two significantly different altitudes. Methods A prospective cohort, a two-center study among confirmed adult admitted...
Ortiz-Prado, Esteban, Raul Patricio Fernandez Naranjo, Eduardo Vasconez, Katherine Simbaña-Rivera, Trigomar Correa-Sancho, Alex Lister, Manuel Calvopiña, and Ginés Viscor. Analysis of excess mortality data at different altitudes during the COVID-19 outbreak in Ecuador. High Alt Med Biol. 22:406-416, 2021. Background: It has been speculated that living high altitude confers some risk reduction terms SARS-CoV-2 infection, reduced transmissibility, arguable lower COVID-19-related mortality....
Abstract In this study, two vacuum frying conditions (VF) were evaluated for their impact on the chemical characteristics, acrylamide content, starch digestibility, and instrumental sensory texture of three corn varieties (Local maize, INIAP-193, INIAP-122). addition, INIAP-193 was fried under deep-fat (DF) because it is most widely used preparation technique saccharate variety effect nutritional colour components assessed. The lowest moisture content highest lipid found in DF. Frying led to...
Adipose tissue, in addition to serving as energy storage, can store lipophilic substances, some of which may pose a health risk if massively mobilized during rapid weight loss. This study aimed biomonitor inorganic elements obese patients undergoing bariatric surgery and analyze the role sociodemographic factors. ICP-MS was employed quantify 55 elements, including identified from ATSDR’s Substance Priority List rare-earth serum samples 58 before after surgery. A total 39 out were detected,...
Suicide affects people from different backgrounds, ethnical groups, socio-economic status and geographical locations. In Latin America, suicide reports arescarce, specially in Andean countries. Ecuador, very few have partially described this phenomenon, nonetheless, estimation of the burden disease (BoD) hasnever been reported country. A country-wide comparison was performed using Ministry Public Health's national databases overall mortality, Hospital Discharges Database, Population Census...
The reference values for lung function are associated to anatomical and morphology parameters, but anthropometry it is not the only influencing factor: altitude genetics two important agents affecting respiratory physiology. Altitude its influence on has been studied independently of genetics, considering early long-term acclimatization.
Thyroid cancer is the most frequent endocrine neoplasia worldwide. Information from Andean countries scarce. In Ecuador there no reports available of epidemiology this type cancer. The aim study to present and burden disease thyroid cancer.This a cross-sectional population-based analysis in 2001 2016. variables studied were overall mortality rate, socio-demographics characteristics hospitalized patients, geographical trends Ecuador. All data was obtained official records reported by Ministry...
Abstract Background The relentless advance of the SARS-CoV-2 virus pandemic has resulted in a significant burden on countries, regardless their socio-economic conditions. infected more than 2.5 million people worldwide, causing to date 150,000 deaths over 210 countries. Objective aim this study was describe trends cases, tests and related novel coronavirus disease (COVID-19) Latin American Caribbean (LAC) Methodology Data were retrieved from WHO-Coronavirus Disease (COVID-2019) situation...
Abstract Background The SARS-CoV-2 virus has spread rapidly around the globe. Nevertheless, there is limited information describing characteristics and outcomes of COVID-19 patients in Latin America. Methods We conducted a cross-sectional analysis 9,468 confirmed cases reported Ecuador. calculated overall incidence, mortality, case fatality rates, disability adjusted life years, attack crude mortality as well relative risk odds death, for age, sex presence comorbidities. Results A total...
Introduction: Worldwide, more than 5.7% of the population reside above 1,500 m elevation. It has been hypothesized that acute short-term hypoxia exposure could increase risk developing a stroke. Studies assessing effect altitude on stroke have provided conflicting results, some analyses suggest long-term chronic be associated with reduced mortality and lower incidence rates. Methods: An ecological analysis all hospital admissions, rates, disability-adjusted life years in Ecuador was...
Background: There is pressing urgency to identify therapeutic targets and drugs that allow treating COVID-19 patients effectively. Methods: We performed in silico analyses of immune system protein interactome network, single-cell RNA sequencing human tissues, artificial neural networks reveal potential for drug repurposing against COVID-19. Results: screened 1,584 high-confidence proteins ACE2 TMPRSS2 co-expressing cells, finding 25 significantly overexpressed nasal goblet secretory lung...
Abstract Background The eruption of the Tajogaite volcano began on island La Palma September 19, 2021, lasting for 85 days. This study aims to present design and methodology ISVOLCAN (Health Impact Population due Volcanic Eruption) cohort, as well preliminary findings from first 1002 enrolled participants. Methods A prospective cohort was conducted with random selection adult participants general population, an estimated sample size 2600 individuals. results 857 are presented, along a group...
<b><i>Objective:</i></b> Traumatic brain injury (TBI) is a public health problem worldwide. Information regarding TBI from low- and middle-income countries scarce. The objectives of this study are to determine the incidence, mortality geodemographic distribution in Ecuador. <b><i>Methods:</i></b> A population-based analytical 2004 2016 was conducted Men women with diagnosis all ages (0–110 years) were included. Data obtained official...
Background Radiology is a useful tool for diagnosis and intervention in medical practice, all the components within teaching-learning process of this subject during undergraduate studies influence successful knowledge application.Objective This study aimed to describe level radiology students last two years school curricular characteristics their courses seven Latin American countries.Methods A multicenter cross-sectional was carried out on 7 countries (Bolivia, Brazil, Colombia, Ecuador,...
The growth of COVID-19 pandemic throughout more than 213 countries around the world have put a lot pressures on governments and health services to try stop rapid expansion pandemic. During 2009, H1N1 Influenza pandemic, statistical mathematical methods were used track how virus spreads countries. Most these models that developed at beginning XXI century are based classical susceptible-infected-recovered (SIR) model almost hundred years ago. evolution this allows us forecast compute basic...
Introduction: Human adaptation to high altitude is due characteristic adjustments at every physiological level. Differences in lipid profile and cardiovascular risk factors dwellers have been previously explored. Nevertheless, there are no reports available on genotype-controlled matches among different altitude-adapted indigenous populations. Objective: To explore the possible differences plasma autochthonous Kiwcha people inhabitants of low high-altitude locations. Methodology: A...
Abstract Background Gender–based violence is a major public health concern arising from the structural discrimination of women and girls. In 2014, Ecuador criminalized acts femicide in response to growing crisis across region. As no epidemiological studies on state female homicides femicides have been published, we estimated patterns nationally burden through economic cost per years life lost, between 2001 2017. Methods Using aggregated data National Institute Census Statistics police...
The COVID-19 pandemic has put a lot of pressure on health systems worldwide. Mass vaccination against SARS-CoV-2 reduced morbidity and mortality Despite their safety profiles, vaccines, as with any other medical product, can cause adverse events. Yet, in countries poor epidemiological surveillance monitoring systems, reporting vaccine-related events is challenge. objective this study was to describe self-reported vaccine after receiving one the available schemes Ecuador. A cross-sectional...
Ortiz-Prado, Esteban, Katherine Simbaña-Rivera, Diego Duta, Israel Ochoa, Juan S. Izquierdo-Condoy, Eduardo Vasconez, Kathia Carrasco, Manuel Calvopiña, Ginés Viscor, and Clara Paz. Optimism health self-perception-related differences in indigenous Kiwchas of Ecuador at low high altitude: a cross-sectional analysis. High Alt Med Biol. 23:26-36, 2022. Background: Living altitude causes adaptive responses every physiological molecular level within the human body. Emotional psychological short-...
Many primary-tumor subregions exhibit low levels of molecular oxygen and restricted access to nutrients due poor vascularization in the tissue, phenomenon known as hypoxia. Hypoxic tumors are able regulate expression certain genes signaling molecules microenvironment that shift it towards a more aggressive phenotype. The transcriptional landscape tumor favors malignant transformation neighboring cells their migration distant sites. Herein, we focused on identifying key proteins participate...