A5101946446- Sleep and related disorders
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Extracellular vesicles in disease
- Health disparities and outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Nutritional Studies and Diet
- Epigenetics and DNA Methylation
- Folate and B Vitamins Research
- Kruppel-like factors research
- Adenosine and Purinergic Signaling
- Pulmonary Hypertension Research and Treatments
- Neurological Disease Mechanisms and Treatments
- Eating Disorders and Behaviors
- Urban, Neighborhood, and Segregation Studies
- Circadian rhythm and melatonin
- Genetic Syndromes and Imprinting
- Traditional Chinese Medicine Studies
- Intergenerational Family Dynamics and Caregiving
- Psychological Well-being and Life Satisfaction
- Literature, Language, and Rhetoric Studies
- Ovarian function and disorders
- Diet, Metabolism, and Disease
- Endoplasmic Reticulum Stress and Disease
- Acupuncture Treatment Research Studies
Ningxia Medical University
2017-2025
Ningxia Medical University General Hospital
2024-2025
Chongqing Medical University
2024
Shenzhen Maternity and Child Healthcare Hospital
2024
Third People 's Hospital of Chongqing
2009
Harbin Normal University
2009
Cerner (United States)
2007
University of Alabama at Birmingham
2007
University of Florida
2007
Lynn University
2007
Trouble sleeping is one of the major health issues nowadays. Current evidence on correlation between muscle quality and trouble limited.A cross-sectional study design was applied participants aged from 18 to 60 years in National Health Nutrition Examination Survey (NHANES) 2011-2014 used for analysis. Muscle index (MQI) quantitatively calculated as handgrip strength (HGS, kg) sum/ arm appendicular skeletal mass (ASM, by using sum non-dominant hand dominant hand. Sleeping data obtained...
Abstract Background Myocardial infarction (MI) represents a severe cardiovascular disease with limited therapeutic agents. This study was aimed to elucidate the role of exosomes derived from human placental mesenchymal stem cells (PMSCs-Exos) in MI. Methods PMSCs were isolated and cultured vitro, identification by both transmission electron microscopy (TEM) nanoparticle tracking analysis (NTA). To further investigate effects PMSC-Exos on MI, C57BL/6 mice randomly divided into Sham group, MI...
Atherosclerosis (AS) is closely associated with abnormally chronic low-grade inflammation and gut dysbiosis. Flaxseed oil (FO) rich in omega-3 polyunsaturated fatty acids (PUFAs), which are mainly composed of alpha-linolenic acid (ALA, 18:3 omega-3), has been demonstrated to exhibit pleiotropic benefits metabolic diseases. However, the impact dietary ALA-rich FO on AS its underlying mechanisms remain poorly understood. Thus, present study was designed as two phases investigate effects...
Background With the rapid urbanization in many countries, more attention is being paid to relationship between and mental health, especially depression. However, countries with urbanization, few empirical studies exist on adolescent Methods Nationally representative survey data from China Family Panel Studies 2012, 2016 2018 were used. Data of 1,588 adolescents obtained 25 provinces. Depression was measured using Center for Epidemiology 20-item score. The rate National Bureau Statistics...
<title>Abstract</title> Background Chest Pain Centers (CPC) demonstrated improved outcomes for patients with acute myocardial infarction (AMI) globally. However, the long-term impact of CPC establishment in economically developing areas, such as Ningxia, China, remains unclear. This study aimed to assess prognosis and efficacy collaborative regional rescue systems centered on ST-segment elevation (STEMI) Ningxia. Methods retrospective cohort analyzed 5,344 STEMI from Ningxia Myocardial...
One of the main characteristics atherosclerosis is vascular calcification, which linked to adverse cardiovascular events. Increased homocysteine (Hcy), a feature hyperhomocysteinemia, correlated with advanced calcification and phenotypic switching smooth muscle cells (VSMCs). Oxidative stress high phosphate levels also induce VSMC suggesting that Krüppel-like factor 4 (KLF4) signaling pathway may contribute calcification. In this study, we investigated possibility role mechanisms Hcy in We...
Hyperhomocysteinemia (HHcy) is an independent risk factor for atherosclerosis and plaque vulnerability. Macrophage apoptosis mediated by endoplasmic reticulum (ER) stress plays important role in the pathogenesis of HHcy-aggravated atherosclerosis. Endoplasmic oxidoreductase 1α (Ero1α) critical ER stress-induced apoptosis. We hypothesized that Ero1α may contribute to ER-stress induced macrophage stability advanced atherosclerotic lesions HHcy.Apoe-/- mice were maintained on drinking water...
Atherosclerosis (AS) is closely associated with chronic low-grade inflammation and gut dysbiosis. Metformin (MET) presents pleiotropic benefits in the control of metabolic diseases, but impacts MET intervention on microbiota AS remain largely unclear. In this study, ApoE -/- mice a high-fat diet (HFD) were adopted to assess treatment. After 12 weeks (100mg·kg -1 ·d ), relevant indications investigated. As indicated by pathological measurements, atherosclerotic lesion was alleviated...
Objective To investigate the associations between geriatric nutritional risk index (GNRI) with cognitive functions among U.S. older adults. (Patients were classified into two nutrition groups based on GNRI). Methods Our analysis utilized data from cross-sectional National Health and Nutrition Examination Survey (NHANES) conducted 2011 2014. Cognitive function was measured using CERAD test, AFT DSST. Composite z -scores obtained by summing test-specific of above three tests used to assess...
FUS plays a significant role as an RNA-binding protein in several cellular processes, including RNA splicing, DNA repair, and transcriptional regulation. However, the capacity of atherosclerosis is unclear. We aimed to study functions inflammatory regulation through splicing factor. knocked down with siRNA further overall level select alternative (AS) human umbilical vein endothelial cells (HUVECs) by sequencing. The results suggested that knockdown significantly affected gene expression...
Abstract Objective Triglyceride glucose (TyG) index is considered as a new alternative marker of insulin resistance and clinical predictor type 2 diabetes mellitus (T2DM) combined with coronary artery disease. However, the prognostic value TyG on No-Reflow (NR) Phenomenon in T2DM patients acute myocardial infarction (AMI) remains unclear. Methods In this retrospective study, 1683 AMI underwent primary percutaneous intervention (PCI) were consecutively included between January 2014 December...
<title>Abstract</title> Multiple mechanisms of mitochondrial dysfunction have been implicated in the pathogenesis pulmonary hypertension (PH). Thus, this study aims to identify biomarkers associated with mitochondrial-related genes (MRGs) patients PH. The GSE33463 (blood training set), GSE15197 (tissue GSE113439 (external validation set) and MRGs were all acquired from public databases. Differential expression analysis was undertaken selected differentially expressed (DEGs) blood tissue set,...
<title>Abstract</title> Background The relationship between mitral regurgitation (MR) and long-term outcomes in Chinese patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) remains scarce. This study aims to elucidate the connection MR clinical following AMI treated PCI. Design methods: In this retrospective 6940 who were diagnosed consecutively enrolled from General Hospital of Ningxia Medical University(2014–2019). included divided into no MR,...
Sitting time and physical activity are related to renal function among type 2 diabetes mellitus (T2DM); however, the mechanism of how it contributes is not well understood. The current study attempts explore relationship between sitting T2DM patients, with a particular focus on mediating role activity.This research uses data 1761 Chinese patients from Ningxia Province. were obtained during face-to-face survey, was assessed by estimated glomerular filtration rate (eGFR). bootstrap method used...
Objective: The study aims to reveal the association between family context and sleep trajectories in middle-aged elderly Chinese adults. Methods: Subjects (n=7777) aged 40 65 years were selected from China Family Panel Studies (CFPS). Latent class analysis multi-trajectory method used identify 2010 2018. Multinomial (polytomous) logistic regression was performed explore relationship trajectories. Results: Five classes identified according demographic characteristics. Simultaneously, four...
Purpose: To assess health-related quality of life (HRQOL) among GERD patients stratified by symptom severity and nighttime symptoms. Methods: A sample US adults participated in a web survey including validated screener. Frequency daytime heartburn acid regurgitation during the previous 3 months were each assessed. The highest value reported for symptoms or was assigned to (10-point Likert scale). Severity classification was: mild (1–4), moderate (5–7) severe (8–10). Nighttime (NTG) cases...
Traditional Chinese medicine (TCM) plays a major role in preventing and treating the disease, however, it is also facing slice of challenges as fewer choices TCM treatment. Although lifestyles health conditions might be paramount influencing factors for choice treatment, relative evidence scarce. The current observational study was designed to evaluate this association. A total 24,173 individuals with mean age 47.3 years from Family Panel Studies 2014 were selected. treatment acquired by...