A5101495726- Plant Molecular Biology Research
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Lung Cancer Diagnosis and Treatment
- Plant Reproductive Biology
- Plant Gene Expression Analysis
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- HER2/EGFR in Cancer Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Medical Imaging and Analysis
- Esophageal Cancer Research and Treatment
- Colorectal and Anal Carcinomas
- Cardiovascular and Diving-Related Complications
- Spine and Intervertebral Disc Pathology
- Metastasis and carcinoma case studies
- Musculoskeletal pain and rehabilitation
- Reliability and Maintenance Optimization
- Light effects on plants
- Plant Stress Responses and Tolerance
- Inflammatory Biomarkers in Disease Prognosis
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism
- Autophagy in Disease and Therapy
- Personality Traits and Psychology
Ministry of Agriculture and Rural Affairs
2020-2025
Nanjing Agricultural University
2019-2025
University of Montevallo
2023-2024
Henan Normal University
2024
King Abdullah University of Science and Technology
2024
Athinoula A. Martinos Center for Biomedical Imaging
2024
Harvard University
2024
Massachusetts General Hospital
2024
Xi'an Jiaotong University
2010-2024
Xi'an Medical University
2024
// Junyun Wang 1,2,* , Nan Ding Yongjun Li 1,* Hua Cheng 3,* Dong 4 Qiong Yang 1,2 Youhui Deng Yaran 1 Yanming Xiuyan Ruan Fang Xie Zhao and Xiangdong CAS Key Laboratory of Genome Sciences Information, Beijing Institute Genomics, Chinese Academy Sciences, Beijing, China 2 University 3 Biology, Hebei Shijiazhuang, Department Dermatology, General Hospital People's Liberation Army, * These authors have contributed equally to this work Correspondence to: Fang, email: Zhao, Keywords : IGFBP5;...
Systemic inflammatory parameters, such as the elevator PLR (platelet-lymphocyte ratio), NLR (neutrophil-lymphocyte ratio) and platelet count (PLT), have been found to be associated with prognosis in gastric cancer; however, these results, especially those relating PLR, remain inconsistent. So we aimed evaluate prognostic role of cancer by conducting presenting findings this meta-analysis.We conducted a systematic literature search PubMed, Embase Cochrane Library value cancer. The quality...
The transition from vegetative to reproductive growth is a key developmental event in plant's life cycle. process mediated by combination of phytohormones, including melatonin (MT) and strigolactone (SL). Here, the Arabidopsis mutants, d14-1 max4-1, which are compromised with respect either SL synthesis or signaling, were shown flower earlier than wild types. tissue MT content both mutants was higher types, as result up-regulation various genes encoding enzymes involved synthesis. abundance...
Purpose: The study aimed to quantify the global trends of incidence rates multidrug-resistant (MDR) tuberculosis (MDR-TB) and extensively drug-resistant (XDR) (XDR-TB). Methods: Cases, age-standardized (ASRs), MDR-TB XDR-TB during 2010-2019 were obtained from Global Burden Disease Study 2019. evaluated using estimated annual percentage changes (EAPCs) in ASRs. relationships among ASRs XDR-TB, MDR rate, XDR socio-demographic index (SDI) assessed locally weighted regression Pearson's...
Background Myofibroblast differentiation, characterized by α-smooth muscle actin (α-SMA) expression, is a key process in organ fibrosis, and induced TGF-β. Here we examined whether an anti-fibrotic agent, N-acetyl-seryl-aspartyl-lysylproline (Ac-SDKP), can regulate induction of TGF-β signaling myofibroblast differentiation as potential component its mechanism vivo vitro. Methodology/Principal Findings Rat pulmonary fibroblasts were cultured vitro divided to 4 groups 1) control; 2) TGF-β1; 3)...
Abstract The flowering time of Chrysanthemum morifolium predominantly depends on day length but is also sensitive to ambient temperature. However, the mechanisms underlying response chrysanthemum temperature are mainly unknown. This study identified a MADS-box transcription factor called CmFLC-like, representative low temperature-responsive induced in leaves and shoot apical meristems at 15°C. Subsequently, CmFLC-like localizes cell nucleus membrane functions as transcriptional repressor....
The lymphatic system plays a critical role in melanoma metastasis, and yet, virtually no information exists regarding the cellular molecular mechanisms that take place between cells vasculature. Here, we generated B16-F1 expressed high (B16α4+) negligible (B16α4-) levels of α4 integrin to determine how expression integrins affects tumor cell interactions with endothelial vitro it impacts metastasis vivo. We found direct correlation on their ability form adhesive monolayers cells. Adhesion...
Abstract Floral transition, the switch from vegetative to reproductive growth, is extremely important for growth and development of flowering plants. In summer chrysanthemum, CmBBX8, a member subgroup II B‐box (BBX) family, positively regulates transition by physically interacting with CmERF3 inhibit CmFTL1 expression. this study, we show that CmBBX5, I comprising two B‐boxes CCT domain, interacts CmBBX8. This interaction suppresses recruitment CmBBX8 locus without affecting its...
Abstract Background The ribonucleotide reductase M1 (RRM1) gene encodes the regulatory subunit of reductase, molecular target gemcitabine. overexpression RRM1 mRNA in tumor tissues is reported to be associated with gemcitabine resistance. Thus, single nucleotide polymorphisms (SNPs) are potential biomarkers response chemotherapy. We investigated whether expression peripheral blood mononuclear cells (PBMCs) or SNPs were clinical outcome after gemcitabine-based chemotherapy advanced non-small...
Treating the vascular elements within neurovascular unit is essential for protecting and repairing brain after stroke. Acute injury on endothelial systems results in disruption of blood-brain barrier (BBB), while post-ischemic angiogenesis plays an important role delayed functional recovery. Here, we considered alterations microvessel integrity to be targets recovery, tested natural compound morroniside as a therapeutic approach restore injured tissue rat model focal cerebral ischemia....
Drug use disorders are an important issue worldwide. Systematic attempts to estimate the global incidence of drug rare. We aimed determine and their trends.We obtained annual incident cases age-standardised rate (ASR) from 1990 2017 using Global Health Data Exchange query tool. The estimated percentage changes ASR were used quantify evaluate trends in rate. Gaussian process regression Pearson's correlation coefficient assess relationship between socio-demographic index (SDI).The number...
Plants employ several endogenous and exogenous signals to guarantee timely floral transitions with integrators. To avoid premature flowering, flowering plants must control the balance between vegetative development. As a Group II member of BBX family, CmBBX8 promotes by directly activating CmFTL1 in summer-flowering chrysanthemum. However, mechanisms underlying this transition is yet be elucidated. Here, we report that chrysanthemum ERF3 homologue, CmERF3, physically interacts through yeast...
Chrysanthemum (Chrysanthemum morifolium) is an ideal model species for studying petal morphogenesis because of the diversity in flower form across varieties; however, molecular mechanisms underlying development are poorly understood. Here, we show that brassinosteroid transcription factor BRI1-EMS-SUPPRESSOR 1 (CmBES1) chrysanthemum (C. morifolium cv. Jinba) important organ boundary formation it represses identity genes. plants overexpressing CmBES1 displayed increased fusion outermost ray...