A5027229361- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Otitis Media and Relapsing Polychondritis
- Infectious Aortic and Vascular Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Chronic Myeloid Leukemia Treatments
- Melanoma and MAPK Pathways
- Atherosclerosis and Cardiovascular Diseases
- Eosinophilic Disorders and Syndromes
- Infectious Diseases and Tuberculosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chemotherapy-related skin toxicity
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Surgical site infection prevention
- Drug-Induced Hepatotoxicity and Protection
- Kawasaki Disease and Coronary Complications
- Mitochondrial Function and Pathology
- Neurological diseases and metabolism
- ATP Synthase and ATPases Research
- Aortic aneurysm repair treatments
- Aortic Thrombus and Embolism
- Renal and Vascular Pathologies
- Sarcoidosis and Beryllium Toxicity Research
- Inflammatory Myopathies and Dermatomyositis
- Cerebrovascular and genetic disorders
Centre Hospitalier Saint-Denis
2024-2025
Hôpital Avicenne
2024
Université Paris Cité
2014-2023
Hôpital Cochin
2015-2023
Hôpital Bichat-Claude-Bernard
2016-2023
Assistance Publique – Hôpitaux de Paris
2016-2022
Hôpital Européen Georges-Pompidou
2022
Délégation Paris 7
2014-2020
Hôpital Saint-Louis
2020
Délégation Paris 5
2016-2019
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but frequently cause immune-related adverse events (IrAEs). ICI-induced large vessel vasculitis (LVV) is a rare IrAE, with limited available data. We aimed to describe and compare clinical characteristics evolution of LVV primary LVV. This retrospective, multicentre European study included adult patients who developed after ICI therapy between March 2018 August 2024. Patients were compared matched controls was defined...
Objective Temporal arteritis (TA) is a typical manifestation of giant cell (GCA). Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitides (AAVs) are rarely revealed by TA manifestations, leading to risk misdiagnosis GCA and inappropriate treatments. This study was undertaken describe the clinical, biologic, histologic presentations outcomes in cases revealing AAV (TA‐AAV) compared controls with classic GCA. Methods In this retrospective case–control study, characteristics patients...
Neutrophilic eccrine hidradenitis (NEH) is a rare neutrophilic dermatosis, first described in patients undergoing chemotherapy for malignant haemopathy. It has polymorphous clinical features and the association of both histological necessary to make diagnosis. We report two cases NEH treated with BRAF inhibitor (BRAFi), either dabrafenib or vemurafenib, stage IV metastatic melanoma. Disseminated erythematous plaques associated fever polyarthralgia occurred early after initiation treatment...
Abstract Heterozygous missense HTRA1 mutations have been associated with an autosomal dominant cerebral small vessel disease (CSVD) whereas the pathogenicity of heterozygous stop codon variants is unclear. We performed a targeted high throughput sequencing all known CSVD genes, including HTRA1, in 3853 unrelated consecutive patients referred for molecular diagnosis. The frequency leading to premature this patient cohort was compared their large control databases. An analysis mRNA several...
GCA is a large vessel vasculitis for which triggering factors remain unknown. Clonal haematopoiesis (CH) was associated with atherosclerosis through the induction of inflammation in myeloid cells, and data suggest that CH expansion may support each other to induce pro-inflammatory loop. Our objective describe impact JAK2p.V617F-mutated myeloproliferative neoplasms (MPNs) on screen MPN-free patients mutations.We performed retrospective case-control study comparing characteristics 21 MPN 42...
A 36-year-old male ex-smoker was referred for the management of pulmonary Langerhans cell histiocytosis (LCH) confirmed by surgical biopsy (figure 1A). He had been treated with desmopressin 5 years diabetes insipidus. One year before admission, dyspnoea on exertion appeared. At same time, patient developed painful nail abnormalities all 10 fingers subungual hyperkeratosis, purpuric striae, paronychial erythema, longitudinal grooving, splinter haemorrhages, onycholysis, lunula deformation...
Background: The new 2019 SLE European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) classification criteria for systemic lupus erythematosus (SLE) have been recently published. Seritis is a prominent -often inaugural- feature active SLE. Low titers antinuclear antibodies (ANA) frequently reported in patients with idiopathic pericarditis. Of note, ANA positivity at titer ≥1/80 now mandatory as an entry criterion the EULAR/ACR criteria. Objectives: Although...