- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- Hippo pathway signaling and YAP/TAZ
- Childhood Cancer Survivors' Quality of Life
- Hair Growth and Disorders
- Immune responses and vaccinations
- 3D Printing in Biomedical Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Congenital heart defects research
- Plant Molecular Biology Research
- Fibroblast Growth Factor Research
- Skin and Cellular Biology Research
- Electrospun Nanofibers in Biomedical Applications
- Immune Response and Inflammation
University of Copenhagen
2021-2022
Novo Nordisk Foundation
2021
Organ Recovery Systems (Belgium)
2019-2021
KU Leuven
2019-2021
Vietnam National University Ho Chi Minh City
2021
Health and Human Development (2HD) Research Network
2018
Accurate fluid pressure in the fetal lung is critical for its development, especially at beginning of saccular stage when alveolar epithelial type 1 (AT1) and 2 (AT2) cells differentiate from progenitors. Despite our growing understanding role physical forces molecular mechanisms that regulate transduction mechanical stretch to differentiation remain elusive. To simulate distension, we optimized both an ex vivo model with precision cut slices tracheal occlusion. Increased tension showed...
Background Pulmonary hypoplasia, characterized by incomplete alveolar development, remains a major cause of mortality and morbidity in congenital diaphragmatic hernia. Recently demonstrated to differentiate from common bipotent progenitor during the two cell types that line alveoli type 1 2 cells have shown alter their relative ratio hernia lungs. Objective We used nitrofen/bisdiamine mouse model induce accurately assess status epithelial differentiation relation progenitors. Study design...
Today, stem cell therapy has been shown to be a remarkable progress and an important application in the regeneration of defective tissues organs. To deliver cells injured area, several methods have proposed such as intravenous infusion, direct damaged tissue injection, or sheet transplantation. In this study, we aimed fabricate by culturing human umbilical cord mesenchymal (hUC-MSCs) on Col-T scaffold recover structure function tissues. The results showed that reach confluent surface 18...