Keiichi Hosaka

ORCID: 0000-0002-8471-358X
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About
Contact & Profiles
Research Areas
  • Dental materials and restorations
  • Dental Research and COVID-19
  • Dental Erosion and Treatment
  • Dental Implant Techniques and Outcomes
  • Endodontics and Root Canal Treatments
  • Dental Anxiety and Anesthesia Techniques
  • Orthodontics and Dentofacial Orthopedics
  • Building materials and conservation
  • Laser Applications in Dentistry and Medicine
  • Bone Tissue Engineering Materials
  • Additive Manufacturing and 3D Printing Technologies
  • Immune Response and Inflammation
  • Oral microbiology and periodontitis research
  • Conservation Techniques and Studies
  • Dental Radiography and Imaging
  • Dental Trauma and Treatments
  • Surgical Sutures and Adhesives
  • NF-κB Signaling Pathways
  • Engineering Technology and Methodologies
  • Bee Products Chemical Analysis
  • Natural product bioactivities and synthesis
  • Antimicrobial agents and applications
  • Cultural Heritage Materials Analysis
  • Dental Education, Practice, Research
  • Genomics, phytochemicals, and oxidative stress

Tokushima University
2021-2025

Massachusetts Institute of Technology
2024

Tokyo Medical and Dental University Hospital
2020-2024

King's College London
2024

St. Thomas Hospital
2024

St Thomas' Hospital
2024

Charles University
2024

Tokyo Medical and Dental University
2013-2023

Al Baha University
2023

Universidade Federal dos Vales do Jequitinhonha e Mucuri
2023

This study evaluated the effect of structural color phenomenon in resin composites (RCs) on adjustment restorations by investgating their reproduction performance human incisors various shade. Cervical cavities were filled with a single-shade RC 260 nm spherical fillers (Omnichroma (OMN)), conventional A2-shade RCs (Estelite Σ Quick or Clearfil AP-X), experimental 5–50 fumed silica (R1) and 100 (R2). Color parameters (L*C*h*) measured using CIE XYZ camera along centerline restorations,...

10.4012/dmj.2020-364 article EN Dental Materials Journal 2021-04-19

Higher 24-hour resin-dentin bond strengths are created when ethanol is used to replace water during wet bonding. This in vitro study examined if ethanol-wet-bonding can increase the durability of bonds over longer times. Five increasingly hydrophilic experimental resin blends were bonded acid-etched dentin saturated with or ethanol. Following composite build-ups, teeth reduced into beams for microtensile strength evaluation, and water-aging at 37°C 3, 6, 12 months before additional...

10.1177/0022034508328910 article EN Journal of Dental Research 2009-02-01

Zirconia ceramics have been widely used as dental restorations due to their esthetic appearance and high flexural strength. The bonding of zirconia with resin cement should rely on both mechanical chemical bonds. This study was performed investigate the effect surface topography its wettability after pretreatments microshear bond strength (μSBS) a cement. slabs were prepared randomly divided into 5 groups based treatment follows: no (control), air abrasion (AB), etching hydrofluoric acid...

10.1038/s41598-023-45510-8 article EN cc-by Scientific Reports 2023-10-25

The recently introduced resin composites with a universal shade are claimed to match any tooth color. In this study, it was examined how composite thickness affects the color adjustment of conventional and universal-shade background dentin. Thirty sound human central incisors various were used, differences between their intact labial surfaces, exposed dentin surfaces restorations (thickness 1-3 mm) evaluated. addition, translucency, light transmission characteristics, spectral reflectance...

10.4012/dmj.2022-197 article EN Dental Materials Journal 2023-01-06

The degree of conversion contemporary universal adhesives positively correlates with the bond strength to dentin. correlation is more marked after thermocycling, suggesting that a high required for long-term dentin bonding durability.Purpose: objectives this study were evaluate micro-tensile (μTBS) five 24 hours and thermocycling (TC), measure their degrees (DC) test between μTBS DC.Methods Materials: Four commercially available adhesives, Prime&Bond (PBU), Ecosite Bond (EB), G-Premio (GPB),...

10.2341/19-165-l article EN Operative Dentistry 2020-04-03

The effect of curing mode dual-cure resin cements on the tensile bond strength (TBS) universal adhesives to enamel, dentin, zirconia, lithium disilicate ceramics (LDS), feldspathic porcelain (FP), and a Pd-Au alloy was evaluated. substrates were bonded using Tokuyama Universal Bond (TUB) or Scotchbond Adhesive (SBU), followed by luting with Estecem II (ECII) Rely-X Ultimate (RXU), respectively, which used either in light-curing self-curing mode. TBS test performed after 24 h 5,000 thermal...

10.4012/dmj.2020-077 article EN Dental Materials Journal 2020-11-06

Few studies have reported on the impact of oxidative stress dental implant failure. The aim this study was to investigate hyperglycemia-induced osseointegration in diabetes mellitus (DM).Acid-treated titanium implants were bilaterally placed maxillary alveolar ridge streptozotocin-induced diabetic (DM group) and control rats after extraction first molars. Histological analysis micro-push-out test performed 4 weeks surgery. Oxidative osteogenic markers surrounding bone quantified by real-time...

10.1111/jre.12972 article EN Journal of Periodontal Research 2022-01-17

The color-matching ability of single-shade composites Omnichroma (OMN) and Flow (OCF) is ensured by structural color, which arises from monodisperse 260 nm spherical fillers. This study evaluated how filler load influences the color adjustment potential composite restorations to human teeth various shades. performance containing fillers —OMN (79 wt%), OCF (71 experimental R1 (65 R2 (60 wt%)— was compared two conventional A2-shade a transparent composite. Additionally, translucency parameter,...

10.4012/dmj.2022-199 article EN Dental Materials Journal 2023-01-27

Patients: This case report presents a minimally invasive approach to replace missing mandibular lateral incisor using dual-injection molding technique with flowable composite resins. Integrated comprehensive digital workflow, this method achieves structurally and esthetically biomimetic, bi-layered prosthetic solution. A 34-year-old woman congenital absence of was successfully rehabilitated direct resin-bonded fixed partial denture (RBFPD).

10.2186/jpr.jpr_d_23_00239 article EN cc-by-nc Journal of Prosthodontic Research 2024-01-01

Periodontal disease is a chronic inflammatory caused by periodontopathogenic bacteria, and its progression leads to periodontal tissue destruction tooth loss. Zerumbone bioactive substance found in ginger (

10.1080/08923973.2024.2445724 article EN Immunopharmacology and Immunotoxicology 2025-01-03

Abstract Objective The objective of this study is to disperse europium oxide (Eu 2 O 3) in a resin composite (RC) using planetary centrifugal mixer and assess its effects on photoluminescence mechanical properties. Materials methods A commercially available RC was mixed with Eu 3 at various concentrations mixer. fabricated samples were evaluated scanning electron microscopy spectrofluorometer their crystal structures, particle sizes, Vickers microhardness measurements performed, along...

10.1038/s41405-025-00304-0 article EN cc-by BDJ Open 2025-02-03

The rapid advancement of computer-aided design and manufacturing (CAD/CAM) technology has transformed restorative dentistry, offering materials that combine esthetic quality with mechanical durability for indirect restorations. This mini-review evaluates the fatigue resistance fracture behavior CAD/CAM hybrid materials, particularly under cyclic loading high occlusal forces. analysis encompasses both subtractive (milling) additive (3D printing) methods, emphasizing each method's advantages...

10.12982/osr.2025.040 article EN other-oa Oral Sciences Reports 2025-03-27

PURPOSE To evaluate (1) the initial and long-term microtensile bond strengths of two-step self-etch adhesives with different degrees conversion (DC); (2) elastic modulus respective adhesive resins; (3) water sorption resins. MATERIALS AND METHODS Two adhesives, Clearfil SE Bond (CSE) 2 (CSE2) were used in this study. The DC was determined using ATR/FT-IR a time-based spectrum analysis. Midcoronal flat dentin surfaces 24 human molars prepared 600-grit SiC paper for strength (µTBS) testing....

10.3290/j.jad.a37726 article EN 2017-01-01

The purpose was to evaluate the effect of a hydrophilic amide monomer on μTBS one-step adhesive dentin at different application times. Clearfil Universal Bond Quick (UBQ), experimental (UBQexp; same compositions as UBQ but replaced with 2-hydroxyethyl methacrylate), SE ONE and were applied midcoronal prepared 600-grit SiC time (0, 10, 20 40 s). Water sorption (Wsp) ultimate tensile strength (UTS) polymerized adhesives also measured. showed significantly lower Wsp higher UTS than UBQexp. At...

10.4012/dmj.2018-286 article EN Dental Materials Journal 2019-07-31

Abstract Optical coherence tomography (OCT) can create cross-sectional images of tooth without X-ray exposure. This study aimed to investigate the diagnostic accuracy 3D imaging OCT for proximal caries in posterior teeth. Thirty-six human molar teeth with 51 surfaces visibly 6 intact, 16 slightly demineralized, and 29 distinct carious changes were mounted take digital radiographs images. The sensitivity, specificity area under receiver operating characteristic curve (AUC) diagnosis enamel...

10.1038/s41598-020-72838-2 article EN cc-by Scientific Reports 2020-09-25

Self‐etching primers and adhesives contain very hydrophilic methacrylate monomers that result in high water sorptions by their polymers. Water sorption plasticizes the polymers lowers mechanical properties. The purpose of this work was to rank hydrophilicity a series acidic Hoy's solubility parameters ( δ ) determine if there significant relationship between A six primer blends containing fixed concentration phenyl‐P but variable amounts 2‐hydroxyethyl (HEMA), 2,2...

10.1111/j.1600-0722.2007.00452.x article EN European Journal Of Oral Sciences 2007-06-01

Self‐etching primers and adhesives contain very hydrophilic acidic monomers that result in high water sorption/solubilities of their polymers. However, the chemical composition these products varies widely. The purpose this work was to vary experimental self‐etching determine if sorption/solubility polymers were affected a predictable manner. Hoy's solubility parameters mixtures calculated permit ranking degree hydrophilicity Water measured according ISO 4049. results showed highly...

10.1111/j.1600-0722.2007.00430.x article EN European Journal Of Oral Sciences 2007-02-01

The purpose of this study was to evaluate the effect smear layer characteristics on dentin bonding durability HEMA-free and HEMA-containing one-step self-etch adhesives. Xeno V (XV; HEMA-free), G BOND PLUS (GB; HEMA-free) Clearfil S(3 )Bond (S(3); HEMA-containing), were applied surfaces prepared with either #180- or #600-grit SiC paper according manufacturers' instructions. Bond strengths determined using µTBS test after 24-hour, 6-month, 1-year water storage. In addition, nanoleakage...

10.4012/dmj.2011-001 article EN Dental Materials Journal 2011-01-01

The purpose of this study was to compare the dentin bond strength three self-adhesive cements with smear layer pretreatments using a calcium-chelating agent (EDTA) and deproteinizing solution (NaOCl) evaluate their interfacial characteristics. Smear layer-covered surfaces were pretreated EDTA for 60 s, NaOCl 5 15 or none. Three cements; Clearfil SA luting (Kuraray Medical), Rely X Unicem clicker (3M ESPE) Breeze (Pentron) applied surfaces. After 24-h water storage, shear strengths...

10.4012/dmj.2012-031 article EN Dental Materials Journal 2012-01-01
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