- Advanced X-ray and CT Imaging
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Imaging and Diagnostics
- Cerebral Venous Sinus Thrombosis
- Neural dynamics and brain function
- Advanced MRI Techniques and Applications
- Hearing, Cochlea, Tinnitus, Genetics
- Eating Disorders and Behaviors
- Functional Brain Connectivity Studies
- Acupuncture Treatment Research Studies
- MRI in cancer diagnosis
- Environmental remediation with nanomaterials
- Hepatocellular Carcinoma Treatment and Prognosis
- Adsorption and biosorption for pollutant removal
- Healthcare and Venom Research
- Acute Ischemic Stroke Management
- Traditional Chinese Medicine Studies
- Neuroscience and Music Perception
- Electron Spin Resonance Studies
- Photoacoustic and Ultrasonic Imaging
- Mind wandering and attention
- Catalytic Processes in Materials Science
- Liver physiology and pathology
- Obsessive-Compulsive Spectrum Disorders
- Blood Pressure and Hypertension Studies
Beijing Friendship Hospital
2018-2025
Capital Medical University
2018-2025
Chinese Academy of Sciences
2024
Shanghai Institute of Applied Physics
2024
Shanghai University of Engineering Science
2023
Miami University
2021
Linyi People's Hospital
2016-2017
The computed tomography angiography (CTA) postprocessing manually recognized by technologists is extremely labor intensive and error prone. We propose an artificial intelligence reconstruction system supported optimized physiological anatomical-based 3D convolutional neural network that can automatically achieve CTA in healthcare services. This trained tested with 18,766 head neck scans from 5 tertiary hospitals China collected between June 2017 November 2018. overall accuracy of the...
ABSTRACT Introduction Chronic kidney disease (CKD) is associated with cognitive impairment (CI), yet the exact pathophysiological mechanisms remain unclear. This study aims to investigate alterations in gray matter volume (GMV) and cerebral blood flow (CBF) across CKD stages, identify co‐changed brain regions, explore abnormal seed‐based functional connectivity (FC) patients CKD, correlation between regions neuropsychological test scores. Methods Two hundred eight participants (66 healthy...
Previous resting-state functional magnetic resonance imaging (fMRI) studies have shown neural connectivity alterations after the treatment of tinnitus. We aim to study value baseline features network nodes predict outcomes sound therapy through adjusted narrow band noise. The fMRI data 27 untreated tinnitus patients and matched healthy controls were analyzed. calculated graph-theoretical metric degree centrality (DC) characterize nodes. Therapeutic are determined by changes in Tinnitus...
The aim of this study was to investigate the ability a pixel-to-pixel generative adversarial network (GAN) remove motion artefacts in coronary CT angiography (CCTA) images.Ninety-seven patients who underwent single-cardiac-cycle multiphase CCTA were retrospectively included study, and raw images SnapShot Freeze (SSF) acquired. right artery (RCA) investigated because its are most prominent among all arteries. acquired data divided into training dataset 40 patients, verification 30 test 27...
Background Tinnitus is considered to be triggered by aberrant neural activity in the brain. Sound therapy regarded as a reasonable management option for tinnitus treatment and has been applied clinical setting decades. Hypothesis We hypothesized that sound therapy, commonly used method, would alter functional connectivity (FC) of brain regions models. Study Type Longitudinal. Population Resting‐state MRI data were collected from 27 patients before after 12 weeks therapy. Twenty‐seven age‐...
Purpose. To evaluate the diagnostic performance of deep learning with a multichannel fusion three-dimensional convolutional neural network (MCF-3DCNN) in differentiation pathologic grades hepatocellular carcinoma (HCC) based on dynamic contrast-enhanced magnetic resonance images (DCE-MR images). Methods and Materials. Fifty-one histologically proven HCCs from 42 consecutive patients January 2015 to September 2017 were included this retrospective study. Pathologic examinations revealed nine...
Background There have been recent efforts to characterize brain functional activity features in patients with pulsatile tinnitus (PT). These revealed evidence of aberrant connectivity (FC) the right middle temporal gyrus (MTG) PT prolonged disease duration. Purpose To assess possible predictive effect FC MTG Study Type Retrospective. Population Thirty‐four recent‐onset (RPTIN), 24 long‐term (LPTIN), and 35 age‐, gender‐, education‐matched healthy controls were enrolled. Field...
ObjectivesTo evaluate the efficacy and image processing time of dynamic contrast-enhanced MRI (DCE-MRI) exchange model in liver fibrosis staging compare it to magnetic resonance elastography (MRE).MethodsThe subjects were 45 patients with nonalcoholic fatty disease (NAFLD) who underwent MRE DCE-MRI our hospital. Liver biopsy results available for all patients. Spearman rank correlation coefficients used correlations among MRE, parameters. Quantitative parameters, MRE-derived stiffness...
The brain receives sensory information about food, evaluates its desirability and value, responds with approach or withdrawal. evaluation process of food in the obesity may involve a variety neurocircuit abnormalities integration internal external processing. There is lack consistency results extant reported for aberrant changes that prohibits key alterations to be identified. Moreover, most studies focus on observation neural plasticity function structure, evidence functional structural...
Abstract Background Bulimia nervosa is a recurrent eating disorder with uncertain pathogenesis. Recently, there has been growing interest in using neuroimaging techniques to explore brain structural and functional alterations bulimia nervosa, but the findings of previous studies have great number inconsistencies. Methods Here, we collected anatomical resting‐state magnetic resonance imaging data from 43 patients 34 matched healthy controls (HCs). We applied surface‐based morphology analysis...
Abstract Purpose Bulimia nervosa (BN) is characterized by recurrent binge-eating episodes and inappropriate compensatory behaviors. This study investigated alterations in resting-state surface-based neural activity BN patients explored correlations between brain eating behavior. Methods A total of 26 28 healthy controls were enrolled. Indirect measurement cerebral cortical functional connectivity (FC) analyses performed Surfstat. principal component analysis (PCA) model was used to capture...
This study investigated the expression and regulation of IL-6R in hepatitis B-associated moderate hepatic fibrosis cirrhosis. Liver tissues, peripheral blood monocytes (PBMs) serum were collected from 26 B patients with liver 35 The levels Il-6r mRNA these samples examined by quantitative real-time PCR protein analyzed western blot ELISA. MiRNAs that regulate predicted bioinformatics analysis, validated dual luciferase reporter assay. Compared group, was significantly upregulated at both...
Objectives To simulate hemodynamic changes after extraluminal compression in pulsatile tinnitus (PT) patients with a prominent transverse-sigmoid sinus junction (PTSJ). Methods One patient-specific case was reconstructed based on computed tomography venography (CTV) images of PT patient. The degree served as new index this study. Cases 10, 20, 30, 40, 50, 60, 70, 80, and 90% the control subject were constructed. Steady-state computational fluid dynamics (CFD) assessed. wall pressure...
Introduction. In clinical settings, nodular projection (NP) and cord sign (CS) at the tumor edge irregular nodules (IN) in mesorectum often appeared together with extramural vascular invasion (EMVI). We aim to evaluate diagnostic efficiency of MRI morphology primary predicting EMVI patients rectal cancer (RC). Methods. This retrospective study included 156 RC. Clinical imaging factors including NP tumor’s edge, CS maximal depth (EMD), IN mesorectum, growth pattern, length, range wall invaded...
It is not fully known whether dobutamine commonly clinically used in echocardiography and short-term treatment of congestive heart failure has effect on brain microcirculatory behavior. In this study, we sought to investigate the cerebral haemodynamics healthy volunteers. The results showed that dobutamine-induced stress significantly decreased CBF anterior circulation, mainly frontal lobe. Furthermore, volunteers with high BMI, large BA diameter low SBP during test are more likely have...
Background: Magnetic Resonance Imaging (MRI) data acquisition includes several sequences that might be optimized to reduce the scan time. Objective: This study aimed investigate impact of gadolinium chelate administration timing on duration and image quality in Diffusion-weighted (DWI) T2-weighted (T2WI) during abdominal MRI examinations. Methods: A prospective was conducted from October 2018 May 2020. Study participants were assigned into a conventional group, undergoing with DWI T2WI pre...
Motivation: The relationship between white matter hyperintensity (WMH) and altered cerebral blood flow (CBF) in maintenance hemodialysis patients remains unclear. Goal(s): study aims to explore the regulation of changes for CBF its with WMH burden patients. Approach: Hemodialysis were divided into two groups based on whether their decreased after 3-year therapy. severity was compared groups. Results: Compared increased group, higher deep found group. Impact: This association decrased be...
To evaluate the influence of intravenous contrast agent on diagnostic ability for osteoporosis using CT attenuation measurement in patients with liver cirrhosis.This retrospective study was approved by our institutional review board and informed consent waived. 208 cirrhosis (mean age, 61.25 years ± 9.43 [standard deviation]; range, 30-82 years) who underwent both unenhanced two contrast-enhanced (arterial venous phase) abdominal dual-energy examinations from January 1 to September 1, 2020,...
目的 利用功能磁共振成像(fMRI)揭示针刺人体穴位所致大脑皮层神经生理兴奋的现象. 方法分别针刺足阳明胃经上的伏兔穴(S32,7例)、足三里穴(S36,9例)和足少阳胆经上的阳陵泉穴(G34,7例)、光明穴(G37,8例);其中男27例,女4例;年龄21~48岁,平均29.5岁; MR信号采集运用GE 1.5 T Signa Horizon LX 超导型MR仪;应用单次激发回波平面成像梯度回波序列(GRE-EPI),采集8层与解剖图像完全相同层面的功能图像,扫描参数为:TR 3000 ms,TE 40 ms,翻转角90°,视野24 cm×24 cm,层厚7 mm,间隔0.5 mm,矩阵64×64;图像数据在工作站(SUN,GE Advancd Workstation 3.1)上, 运用功能神经成像分析软件(analysis of functional neuroimage, AFNI)进行处理分析....
Objective: To investigate the effect of blood flow direction and afflux location emissary veins (EVs) on hemodynamics transverse-sigmoid sinus (TS-SS) junction. Methods: A patient-specific geometric model was constructed using computed tomography venography (CTV) 4D MR data from a venous pulsatile tinnitus (PT) patient. New EV models were assembled with at superior, middle inferior portions SS original model, inlet outlet directions applied. Computational fluid dynamics (CFD) simulation...