A5100428490- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Dendrimers and Hyperbranched Polymers
- Hepatitis B Virus Studies
- Cancer Genomics and Diagnostics
- Thin-Film Transistor Technologies
- Pancreatic and Hepatic Oncology Research
- Advanced Nanomaterials in Catalysis
- Pickering emulsions and particle stabilization
- Lanthanide and Transition Metal Complexes
- Semiconductor materials and devices
- Extracellular vesicles in disease
- Enhanced Oil Recovery Techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Hydrocarbon exploration and reservoir analysis
- ZnO doping and properties
- Brain Tumor Detection and Classification
- Advanced MRI Techniques and Applications
- Ferroptosis and cancer prognosis
- Biofuel production and bioconversion
- Food composition and properties
- Silicon Nanostructures and Photoluminescence
- Electrospun Nanofibers in Biomedical Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Drug-Induced Hepatotoxicity and Protection
Soochow University
2025
Chinese Academy of Sciences
2007-2024
University of Chinese Academy of Sciences
2011-2024
Donghua University
2011-2024
Tongji University
2022-2024
China Pharmaceutical University
2020-2024
State Key Laboratory of Natural Medicine
2024
Shanghai Tenth People's Hospital
2022-2024
Sichuan Agricultural University
2024
Institute of Coal Chemistry
2024
Photothermal therapy (PTT) has emerged as a promising cancer therapeutic modality with high specificity, however, its effectiveness is limited by available high-efficiency photothermal agents (PTAs), especially in the second near-infrared (NIR-II) biowindow. Here, based on facile liquid-exfoliated FePS3 nanosheets, highly efficient NIR-II PTA conversion efficiency of up to 43.3% demonstrated, which among highest reported levels typical PTAs. More importantly, such Fe-based 2D nanosheets also...
The big success in marine shale gas exploration and production made China the third country worldwide to commercialize development. However, Upper Ordovician Wufeng Formation Lower Silurian Longmaxi around Sichuan Basin are currently only targets that have realized industrial Great challenges emerging since tremendous resources of facies, continental transitional facies trapped new areas multiple other formations yet be successfully developed. Thus, we find it a great necessity provide...
For the first time, we propose a stackable vertical channel-all-around (CAA) In–Ga–Zn-O field-effect transistor (IGZO FET) for high-density 4F<sup>2</sup> and long-retention 2T0C dynamic random access memory (DRAM) application. The device is fabricated in back-end-of-line (BEOL) compatible process flow where channel gate-stack are deposited by plasma-enhanced atomic layer deposition (PEALD). impact of IGZO cycle ratio plasma power on device’s electrical performance...
A unique dendrimer-assisted approach is reported to create Fe3O4/Au nanocomposite particles (NCPs) for targeted dual mode computed tomography/magnetic resonance (CT/MR) imaging of tumors. In this approach, preformed Fe3O4 nanoparticles (NPs) are assembled with multilayers poly(γ-glutamic acid) (PGA)/poly(l-lysine)/PGA/folic acid (FA)-modified dendrimer-entrapped gold via a layer-by-layer self-assembly technique. The interlayers crosslinked 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide...
We report the use of multifunctional dendrimer-entrapped gold nanoparticles (Au DENPs) loaded with gadolinium (Gd) chelator/Gd(III) complexes and surface-modified thiolated cyclo(Arg-Gly-Asp-Phe-Lys(mpa)) (RGD) peptide for targeted dual-mode computed tomography (CT)/magnetic resonance (MR) imaging small tumors. In this study, amine-terminated generation 5 poly(amidoamine) dendrimers were used as a nanoplatform to be covalently modified Gd chelator, RGD via polyethylene glycol (PEG) spacer,...
Chemodynamic therapy (CDT) that utilizes endogenous hydrogen peroxide (H2O2) to produce reactive oxygen species (ROS) kill cancer cells has shown a promising strategy for malignant tumor treatment. Nevertheless, limited H2O2 levels in the microenvironment often compromise therapeutic benefits of CDT, leading recurrence and metastasis. Herein, second near-infrared (NIR-II) photothermal Fenton nanocatalyst (PFN) was developed activatable magnetic resonance imaging (MRI)-guided synergetic (PTT)...
The Wufeng Formation–Longmaxi Formation in the Sichuan Basin South China is key stratum for shale gas exploration and production. To date, three national demonstration zones have been developed. Nevertheless, there are still some test wells that not yet commercialized. In this study, geological characteristics of commercial non-commercial analyzed, as main controlling factors high-producing (high estimated ultimate recovery; EUR), reasons low-production (low EUR) by dissecting wells. results...
Abstract Metal‐organic frameworks (MOFs) featuring good biocompatibility and tunable microstructures are developed to generate reactive oxygen species (ROS) for nanocatalytic therapy. However, the relatively low catalytic activity of MOF intracellular ion homeostasis, a self‐protective mechanism resist accumulation metal ions, results in undesirable efficacy tumor Herein, therapeutic strategy is introduced breaking iron homeostasis therapy synergy with autophagy amplification‐promoted...
Intratumoral pathogens can contribute to cancer progression and affect therapeutic response. Fusobacterium nucleatum, a core pathogen of colorectal (CRC), is an important cause low efficacy metastasis. Thus, the modulation intratumoral may provide target for therapy metastasis inhibition. Herein, we propose F. nucleatum-modulating strategy enhancing CRC inhibiting lung by designing antibacterial nanoplatform (Au@BSA-CuPpIX), which produced reactive oxygen species (ROS) under ultrasound...
Abstract The characteristics of malignant solid tumors with dense extracellular matrix (ECM) and immunosuppressive microenvironment (IME) seriously restrict the high efficacy precise treatment tumors, leading to increased susceptibility recurrence metastasis. Herein, an ultrasound‐mediated hydrogel delivery platform HA‐F127@Ti‐MOF‐Au/PEG‐TK‐DOX/PFD (abbr. HFTiDP) based on a “sonogenetic‐like technology” is developed, which encapsulates sonosensitizer (Ti‐MOF‐Au), chemotherapeutic prodrug...
Abstract We report a facile approach to fabricating low‐generation poly(amidoamine) (PAMAM) dendrimer‐stabilized gold nanoparticles (Au DSNPs) functionalized with folic acid (FA) for in vitro and vivo targeted computed tomography (CT) imaging of cancer cells. In this study, amine‐terminated generation 2 PAMAM dendrimers were employed as stabilizers form Au DSNPs without additional reducing agents. The formed an core size 5.5 nm covalently modified the targeting ligand FA, followed by...
The development of multifunctional nanoprobes with a targeting capability for efficient molecular imaging tumors still remains great challenge. Herein, we report the synthesis and characterization folic acid (FA)-modified dendrimer-entrapped gold nanoparticles (Au DENPs) via facile polyethylene glycol (PEG) linking strategy in vivo targeted tumor computed tomography (CT) applications. In this study, amine-terminated poly(amidoamine) dendrimers generation 5 (G5.NH2) sequentially modified by...
Summary The major challenge in enhanced oil recovery (EOR) by gas injection is poor volumetric sweep efficiency, mainly due to the high mobility and reservoir heterogeneity. Injecting as a foam increases but maintaining stability within remains challenge. This research evaluates synergistic interaction of one type nanoparticle surfactant increase stability, using concentration ratio two components tune affinity for gas/liquid interface. We test capability two-component system stabilize...