- Liver Disease Diagnosis and Treatment
- Neurobiology and Insect Physiology Research
- Silkworms and Sericulture Research
- Advanced biosensing and bioanalysis techniques
- Silk-based biomaterials and applications
- Crystallization and Solubility Studies
- Migraine and Headache Studies
- Alcohol Consumption and Health Effects
- Natural product bioactivities and synthesis
- Genomics, phytochemicals, and oxidative stress
- Nanoplatforms for cancer theranostics
- Gut microbiota and health
- X-ray Diffraction in Crystallography
- Diet, Metabolism, and Disease
- Curcumin's Biomedical Applications
- Endodontics and Root Canal Treatments
- Adenosine and Purinergic Signaling
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Endoplasmic Reticulum Stress and Disease
- Infant Nutrition and Health
- Trigeminal Neuralgia and Treatments
- GDF15 and Related Biomarkers
- Phytochemistry and biological activity of medicinal plants
- Dental Radiography and Imaging
Qingdao University
2024-2025
Tongji University
2023-2025
Chinese Academy of Agricultural Sciences
2023-2024
Chengdu University of Traditional Chinese Medicine
2019-2024
Chongqing Public Health Medical Center
2024
Chongqing Medical University
2024
Xinjiang Agricultural University
2024
Sichuan Academy of Traditional Chinese Medicine
2024
Wenzhou University
2024
Shenzhen University
2024
Abstract Metal‐organic frameworks (MOFs) featuring good biocompatibility and tunable microstructures are developed to generate reactive oxygen species (ROS) for nanocatalytic therapy. However, the relatively low catalytic activity of MOF intracellular ion homeostasis, a self‐protective mechanism resist accumulation metal ions, results in undesirable efficacy tumor Herein, therapeutic strategy is introduced breaking iron homeostasis therapy synergy with autophagy amplification‐promoted...
This study investigates the effects of steel fiber shape (straight and hooked-end) content (0, 0.5, 1.0, 1.5 vol%) on rheological properties, printability, mechanical performance microstructure 3D printable reinforced high strength concrete (3DP-SFHSC). The results indicate that increase improves behaviors 3DP-SFHSC, but extrudability suffers from reduction when exceeded 1.0 vol% due to significant in yield stress. addition hooked-end fibers enhances compressive 3DP-SFHSC by 8%, 25.7%, 40.4%...
Pulmonary hypertension (PH) is a progressive disease characterized by pulmonary vascular remodeling. Increasing evidence indicates that endothelial-to-mesenchymal transition (EndMT) in artery endothelial cells (PAECs) pivotal trigger initiating this However, the regulatory mechanisms underlying EndMT PH are still not fully understood.
In recent decades, natural compounds derived from herbal medicine or dietary sources have played important roles in prevention and treatment of various diseases attracted more attention. Curcumin, extracted the
Silk glands are specialized in the synthesis of several secretory proteins. Expression genes encoding silk proteins Bombyx mori with strict territorial and developmental specificities is regulated by many transcription factors. In this study, we have characterized B. sage, which closely related to sage fruitfly Drosophila melanogaster. It termed Bmsage; it encodes factor Bmsage, belongs Mesp subfamily, containing a basic helix–loop–helix motif. Bmsage transcripts were detected specifically...
Hepatic stellate cells (HSCs) activation is an important step in the process of hepatic fibrosis. NOX4 and reactive oxygen species expressed HSCs play role liver Forsythiaside A (FA), a phenylethanoid glycoside extracted isolated from Forsythiae Fructus, has significant antioxidant activities. However, it not clear whether FA can inhibiting through regulating NOX4/ROS pathway. Therefore, our purpose to explore effect mechanism on alleviate LX2 were activated by TGF-β1 vitro. MTT assay Wound...
Background: Cognitive impairment (CI) is a common mental health disorder among older adults, and dietary patterns have an impact on cognitive function. However, no systematic researches constructed anti-inflammatory diet (AID) protein-enriched (PED) to explore their association with CI adults in China. Methods: The data used this study were obtained from the 2018 waves of China Longitudinal Health Longevity Survey (CLHLS). We construct AID, PED, calculate scores for CI. use binary logistic...
Numerous researches have revealed a correlation between dietary factors and the development of constipation. This study aimed to investigate association oxidative balance score (DOBS) A cross-sectional was conducted by us based on National Health Nutrition Examination Survey (NHANES) from 2005 2010 including 31,034 individuals who completed constipation questionnaire. The DOBS calculated 16 factors, containing 14 antioxidants two prooxidants. Multiple logistic regression restricted cubic...
Thrombus is considered to be the pathological source of morbidity and mortality cardiovascular disease thrombotic complications, while oxidative stress regarded as an important factor in vascular endothelial injury thrombus formation. Therefore, antioxidative maintaining normal function cells are greatly significant regulating tension a nonthrombotic environment. Leonurine (LEO) unique alkaloid isolated from Leonurus japonicus Houtt (a traditional Chinese medicine (TCM)), which has shown...
Abstract Background Migraine is one of the world’s most prevalent and disabling diseases. Despite huge advances in neuroimaging research, more valuable markers are still urgently needed to provide important insights into brain mechanisms that underlie migraine symptoms. We therefore aim investigate regional iron deposition subcortical nuclei migraineurs as compared controls its association with migraine-related pathophysiological assessments. Methods A total 200 (56 chronic [CM], 144...
Using ligand-protected metallic nanoclusters with atomic precision as catalysts and elucidating its ligand effect in the catalysis are prerequisites to deepen structure-catalysis relationship of at molecular level. Herein, a series Ag33 protected different thiolate ligands (2-phenylethanethiol, 4-chlorobenzyl mercaptan, 4-methoxybenzyl mercaptan precursors) were synthesized used heterogeneous for conversion nitroarenes arylamine NaBH4 reductant. The obtained exhibited ligand-dependent...
Transition metal oxides (TMOs) are widely studied for loading of various catalysts due to their low cost and high structure flexibility. However, the prevailing close-packed nature most TMOs crystals has restricted available sites surface only, while internal bulk lattice remains unactuated inaccessible narrow space that blocks out key reactants and/or particulate catalysts. Herein, using tunnel-structured MnO
Abstract Background Small cell lung cancer (SCLC) is a highly aggressive subtype with poor survival and limited treatment options. Sequencing results have revealed gene mutations associated SCLC, however, the correlation between genomic alterations clinical prognosis of SCLC yet unclear. Methods Targeted next-generation sequencing 62 related genes was performed on 53 samples. The correlations outcomes were analyzed. Results 38/62 (61.3%) candidate harbored some alterations, while all samples...