A5100626403- Liver Disease Diagnosis and Treatment
- Phytochemistry and biological activity of medicinal plants
- Pharmacological Effects of Natural Compounds
- Liver physiology and pathology
- Smart Agriculture and AI
- MicroRNA in disease regulation
- Plant-based Medicinal Research
- Gut microbiota and health
- Circular RNAs in diseases
- Phytochemistry and Biological Activities
- Drug-Induced Hepatotoxicity and Protection
- Ginger and Zingiberaceae research
- Cancer-related molecular mechanisms research
- Traditional Chinese Medicine Analysis
- Diet and metabolism studies
- Genomics, phytochemicals, and oxidative stress
- Leaf Properties and Growth Measurement
- Spectroscopy and Chemometric Analyses
- Natural product bioactivities and synthesis
- Neuroinflammation and Neurodegeneration Mechanisms
- Microplastics and Plastic Pollution
- Cancer Immunotherapy and Biomarkers
- Medical Research and Treatments
- Remote Sensing in Agriculture
- Cannabis and Cannabinoid Research
Chengdu University of Traditional Chinese Medicine
2015-2025
Hunan Agricultural University
2018-2025
Southwestern Institute of Physics
2021-2025
Shenyang The Fourth Hospital of People
2025
The Fourth People's Hospital
2025
Xinjiang Academy of Agricultural and Reclamation Science
2023-2024
Ministry of Agriculture and Rural Affairs
2023-2024
Ningxia Medical University
2021-2024
South China Agricultural University
2024
Beijing Tongren Hospital
2018-2024
Artemisia argyi leaf is a well-known species in traditional Chinese medicine, and its essential oil (AAEO) has been identified to exert various physiological activities. The aim of this study was investigate the effects AAEO on lipid metabolism potential microbial role high-fat diet (HFD)-fed mice. A total 50 male mice were assigned five groups for feeding with control (Con), (HFD), HFD plus low (LEO), medium (MEO), high (HEO) doses AAEO. results demonstrated that dietary markedly increased...
Alcoholic liver disease (ALD) is a multifaceted process that involves excessive lipid, reactive oxygen species (ROS) production, unbalanced mitochondrial homeostasis, and ultimate cell death. Quercetin dietary phytochemical presented in various fruits vegetables, which has anti-inflammatory antioxidant effects. According to recent advances pharmanutritional management, the effects of quercetin on processes have attracted attention. In study, we explored whether could attenuate...
Liver fibrosis (LF) is an important stage in chronic liver disease development, characterized by hepatic stellate cell (HSC) activation and excessive extracellular matrix deposition. Phillygenin (PHI), active component the traditional Chinese medicine Forsythiae Fructus with a significant anti-inflammatory effect, has been proved to inhibit HSC activation. Macrophages can polarize pro-inflammatory M1 phenotype M2 phenotype, participating LF development. Currently, its many components have...
The gut microbiota consistently shows strong correlations with lipid metabolism in humans and animals, whether the contributes to muscle fatty acid (FA) deposition meat traits farm animals has not been fully resolved. In this study, we aimed unveil microbial mechanisms underlying FA pigs. First, systematically revealed correlation between microbiome levels 43 obese Ningxiang pigs 50 lean Duroc Landrace Yorkshire (DLY) Mutual fecal transplantation showed that pig-derived increased content...
Acute lung injury (ALI) is a disease characterized by inflammation and still requires further drug development. Forsythiaside A as the active compound of Forsythiae Fructus has therapeutic potential for ALI.
MicroRNAs (miRNAs) are small non-coding RNAs that can posttranscriptionally regulate gene expression by targeting messenger RNAs. During miRNA biogenesis, the star strand (miRNA*) is generally degraded to a low level in cells. However, certain miRNA* express abundantly and be recruited into silencing complex expression. Most miRNAs function as suppressive regulators on Group B coxsackieviruses (CVB) major pathogens of human viral myocarditis dilated cardiomyopathy. CVB genome positive-sense,...
Abstract The deactivation effects and mechanism of plasma‐activated water (PAW) against Staphylococcus aureus biofilm the inhibitory effect on regrowth capacity for surviving S. post PAW treatment were investigated in vitro. Systematic measurements bacterial cultivability, metabolic capacity, membrane integrity intracellular reactive oxygen species (ROS) concentration under two different experimental categories carried out after treatment. Considerable discovered both prolonging inducement...
Liver fibrosis is a chronic pathological process that various pathogenic factors lead to abnormal hyperplasia of hepatic connective tissue, and its main feature the excessive deposition extracellular matrix. However, there are currently no drugs approved for treatment liver fibrosis. Phillygenin (PHI), lignan isolated from Forsythiae Fructus, showed potential anti-inflammatory anti-fibrosis effects but mechanisms remain unknown. In view vital role gut microbiota in development fibrosis, this...
Background: The causal evidence of the triglyceride–glucose (TyG) index, as well joint exposure higher glucose and triglyceride on risk cardio-cerebrovascular diseases (CVD), was lacking. Methods: A comprehensive factorial Mendelian randomization (MR) performed in UK Biobank cohort involving 273,368 individuals with European ancestry to assess quantify these effects. MR, MR-PRESSO, MR-Egger, meta-regression, sensitivity analysis, positive control, external verification were utilized....
Liver fibrosis is a chronic and progressive disease with complex pathogenesis related to bile acids (BAs) gut microbiota. Forsythiaside A (FTA), isolated from the traditional Chinese medicine Forsythiae Fructus (Lian Qiao), natural hepatoprotective agent. The purpose of this study was investigate protective effect FTA on carbon tetrachloride (CCl4)-induced liver in mice. induced mice by intraperitoneal injection 2 mL/kg CCl4 three times week for 4 weeks. attenuated CCl4-induced mice, which...
Seed cotton yield and fiber quality are two primary factors that influence the international competitiveness of cotton. To enhance water-nitrogen utilization efficiency promote sustainable production, field experiments were performed in 2020 2021 to explore effects irrigation depth nitrogen (N) fertilization rate on N uptake distribution, seed yield, traits Korla region southern Xinjiang, China. Three depths (W1: 60% ETc, W2: 80% W3: 100% ETc; ETc was crop water consumption) four rates (N0:...