Anastasiia Bludova
A5078392955- Cell Image Analysis Techniques
- Neural dynamics and brain function
- Single-cell and spatial transcriptomics
- Prostate Cancer Treatment and Research
- Nanoplatforms for cancer theranostics
- RNA Research and Splicing
Cold Spring Harbor Laboratory
2020-2021
An essential step toward understanding brain function is to establish a structural framework with cellular resolution on which multi-scale datasets spanning molecules, cells, circuits and systems can be integrated interpreted
Abstract An essential step toward understanding brain function is to establish a cellular-resolution structural framework upon which multi-scale and multi-modal information spanning molecules, cells, circuits systems can be integrated interpreted. Here, through collaborative effort from the Brain Initiative Cell Census Network (BICCN), we derive comprehensive cell type-based description of one structure - primary motor cortex upper limb area (MOp-ul) mouse. Applying state-of-the-art...
Early steps of cancer initiation and metastasis, while critical for understanding disease mechanisms, are difficult to visualize study. Here, we describe an approach study the processes initiation, progression, metastasis prostate (PC) in a genetically engineered RapidCaP mouse model, which combines whole-organ imaging by serial two-photon tomography (STPT) post hoc thick-section immunofluorescent (IF) analysis. STPT enables detection single tumor-initiating cells within entire prostate,...