A5075470796- Cardiac Valve Diseases and Treatments
- Advanced biosensing and bioanalysis techniques
- 2D Materials and Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Infective Endocarditis Diagnosis and Management
- Advanced Photocatalysis Techniques
- MXene and MAX Phase Materials
- Cardiac and Coronary Surgery Techniques
- Biosensors and Analytical Detection
- Membrane Separation Technologies
- Aortic Disease and Treatment Approaches
- Analytical chemistry methods development
- Advanced MIMO Systems Optimization
- Ga2O3 and related materials
- Gold and Silver Nanoparticles Synthesis and Applications
- ZnO doping and properties
- Quantum Dots Synthesis And Properties
- Natural product bioactivities and synthesis
- Monoclonal and Polyclonal Antibodies Research
- Liver Disease Diagnosis and Treatment
- Glycosylation and Glycoproteins Research
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Extracellular vesicles in disease
Wuyi University
2016-2025
Ningbo Medical Center Lihuili Hospital
2018-2025
Ningbo University
2023-2025
Shanghai Institute of Materia Medica
2025
Nanjing University of Chinese Medicine
2025
Chinese Academy of Sciences
2025
Xijing Hospital
2012-2024
Air Force Medical University
2016-2024
Guangzhou University of Chinese Medicine
2024
Anhui Agricultural University
2024
Due to the unique narrow-band red emission and broadband blue light excitation, as well milder synthesis conditions, Mn4+ ion activated fluoride phosphors show great promise for white emitting diode (W-LED) applications. However, belongs a spin-forbidden transition (2Eg → 4A2), it is fundamental challenge synthesize these with high external quantum efficiency (EQE) above 60%. Herein, highly efficient thermally stable phosphor, Cs2SiF6:Mn4+, internal (IQE) of 89% ultrahigh EQE 71%...
Blocking the HER2 signaling pathway has been an effective strategy in treatment of HER2-positive breast cancer. It mainly relies on use monoclonal antibodies and tyrosine-kinase inhibitors. Herein, we present a new strategy, nano molecularly imprinted polymer (nanoMIP). The nanoMIPs, using N-glycans, could bind almost all glycans suppress dimerization with other HER family members, blocking downstream pathways, thereby inhibiting HER2+ cancer growth. In vitro experiments demonstrated that...
A novel green coating method was proposed to prepare composite nanofiltration (NF) membranes with good structural stability and oxidation resistance ability.
Plasmonic nanomaterials have been widely used for photothermal therapy (PTT) of cancer, but their recognition specificity remains challenging. We prepared sialic acid (SA) gold nanorods (AuNRs) targeted cancer PTT. The SA-imprinted AuNRs exhibited good specificity, enabling the killing cells without damaging healthy cells.
Molecularly imprinted polymers (MIPs) are chemically synthesized materials mimicking the recognition of antibodies towards antigens.
A highly efficient and stable QLED using an inorganic WO3 nanoparticle film as a hole injection layer is demonstrated.The resulting nanoparticle-based QLEDs also exhibit superior performance compared to that of the present PEDOT:PSS-based QLEDs. The results indicate nanoparticles are promising solution-processed buffer materials serve strong candidate for technology towards practical applications in next-generation lighting displays.
Glycoproteins play significant roles in many biological processes. Assays of glycoproteins have importance and clinical values, for which immunoassay has been the workhorse tool. However, suffers from some disadvantages, such as poor availability high-specificity antibodies limited stability reagents. Herein, we present an antibody-free enzyme-free approach, called molecularly imprinted polymer (MIP)-based plasmonic immunosandwich assay (PISA), fast ultrasensitive detection trace complex...
Molecularly imprinted polymers (MIPs) and aptamers, as effective mimics of antibodies, can overcome only some drawbacks antibodies. Since they have their own advantages disadvantages, the combination MIPs with aptamers could be an ideal solution to produce hybrid alternatives improved properties desirable features. Although quite a few attempts been made in this direction, facile controllable approach for preparation aptamer–MIP hybrids still remains lacking. Herein, we present new...
First principles calculations by PBE and hybrid HSE06 functional are performed to explore the electronic properties photocatalytic performances of ZnO/graphene-like (g-GeC) vdWHs.
Aged citrus peels (<italic>chenpi</italic>) have been used as a dietary supplement for gastrointestinal health maintenance in China.
Recognition of cancer cells is essential for many important areas such as targeted therapy. Multimonosaccharide-based recognition could be a useful strategy to improve the specificity, but possibility has not been explored yet. Herein we report pattern via multiplexed imaging with monosaccharide-imprinted quantum dots (QDs). Imprinted sialic acid, fucose, and mannose template, respectively, QDs exhibited good specificity toward template monosaccharides. Multiplexed simultaneously stained...
Antibodies specific to glycans are essential in many areas for important fields, including disease diagnostics, therapeutics, and fundamental researches. However, due their low immunogenicity poor availability, pose serious challenges antibody development. Although molecular imprinting has developed into methodology creating mimics with cost better stability, glycan-specific molecularly imprinted polymers (MIPs) still remain rather rare. Herein, we report a new strategy, precision...
A boom of vertical heterostructures (HTSs) with atomically clean interfaces excited the scientists' enthusiasm in materials science and device engineering. In this letter, we perform blue phosphorus (BlueP)/graphene-like GeC (g-GeC) HTS by DFT calculations. Direct bandgap for g-GeC is beneficial applications photoelectronics. The energy levels both water oxidation reduction are within bandgaps two separate monolayers, predicting their significant capacity splitting reactions. type-II band...
An efficient and stable quantum dot light-emitting diode (QLED) with double-sided metal oxide (MO) nanoparticle (NP) charge transport layers is fabricated by utilizing the solution-processed tungsten (WO3) zinc (ZnO) NPs as hole electron layers, respectively. Except for electrodes, all other are deposited a simple spin-coating method. The resulting MO NP-based QLEDs show excellent device performance, peak luminance of 21300 cd/m2 at emission wavelength 516 nm, maximal current efficiency 4.4...
Nucleic acid aptamers, as useful alternatives of antibodies, have found a large range promising applications such affinity separation and bioassays. The screening aptamers is critical for their applications. Aptamers are often screened by an in vitro methodology called SELEX (systematic evolution ligands exponential enrichment). Although numerous methods been established to facilitate the selection, new efficient selection still much needed. Molecularly imprinted polymers, which antibody at...
Abstract The glycosylation pattern of alpha fetoprotein (AFP) paves the basis for precise early diagnosis hepatocellular carcinoma (HCC). However, existing analytical methods ignore contribution terminal sialic acid, which has been reported to be highly connected with HCC. Besides, development diagnostic assays is severely hindered by preparation anti‐glycans antibodies. Molecularly imprinted polymers (MIPs), as synthetic antibody mimics, provide unique strengths address these issues....