- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Attention Deficit Hyperactivity Disorder
- Transcranial Magnetic Stimulation Studies
- Diabetic Foot Ulcer Assessment and Management
- Spine and Intervertebral Disc Pathology
- Osteoarthritis Treatment and Mechanisms
- Autism Spectrum Disorder Research
- Neural and Behavioral Psychology Studies
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- EEG and Brain-Computer Interfaces
- Obsessive-Compulsive Spectrum Disorders
- Mesenchymal stem cell research
- Cardiovascular Health and Disease Prevention
- Pluripotent Stem Cells Research
- Neurological disorders and treatments
- Bone health and treatments
- Parasitic infections in humans and animals
- Cell death mechanisms and regulation
- Advanced Glycation End Products research
- Cerebral Venous Sinus Thrombosis
- S100 Proteins and Annexins
Affiliated Hospital of Hangzhou Normal University
2020-2025
Southern Medical University
2023-2025
Hangzhou Normal University
2020-2024
Zhejiang University
2015-2024
Shanghai Ninth People's Hospital
2023
Shanghai Jiao Tong University
2023
General Hospital of Shenyang Military Region
2023
University Medical Center Hamburg-Eppendorf
2022
Universität Hamburg
2022
I-Shou University
2019
As the multi-center studies with resting-state functional magnetic resonance imaging (RS-fMRI) have been more and applied to neuropsychiatric studies, both intra- inter-scanner reliability of RS-fMRI are becoming increasingly important. The amplitude low frequency fluctuation (ALFF), regional homogeneity (ReHo), degree centrality (DC) 3 main metrics in a way voxel-wise whole-brain (VWWB) analysis. Although intra-scanner (i.e., test-retest reliability) these has widely investigated, few...
Hemichordata is one special kind of invertebrate animal that has many similarities with early vertebrate animals, especially the part their dorsal column. Otherwise, hemichordata have a strong ability regeneration. Regeneration sign which means possibility having totipotent adult stem cells. It widely known cells exist in kinds but they not been found body animals natural nowadays. may to be helpful due its similarity column animals. Dorsal most complex structures animals’ body, and showed...
The contextual cueing effect-where participants search repeated displays faster than novel ones-is often explained by the "attention guidance" account, which posits that exposure helps individuals learn context and attend to likely target locations. Alternatively, "generic procedural learning" account suggests a general strategy is developed for all displays, although contexts play higher weight in optimizing due their presented frequency. This makes responses displays. current study...
<h3>BACKGROUND AND PURPOSE:</h3> The demonstration of prominent medullary veins in the deep white matter ipsilateral to acute ischemic stroke has been shown predict poor clinical outcome. We have investigated prognostic implications patients with subacute who present outside therapeutic window for revascularization therapy. <h3>MATERIALS METHODS:</h3> Forty-three consecutive middle cerebral artery territory presenting within 3–7 days ictus were enrolled. presence periventricular and...
The fast Fourier transform (FFT) is a widely used algorithm to depict the amplitude of low-frequency fluctuation (ALFF) resting-state functional magnetic resonance imaging (RS-fMRI). Wavelet (WT) more effective in representing complex waveform due its adaptivity non-stationary or local features data and many varieties wavelet functions with different shapes being available. However, there paucity RS-fMRI studies that systematically compare between results FFT versus WT. present study...
Osteoarthritis (OA) is a prevalent progressive disorder. Moxibustion has found widespread use in clinical practice for OA, while its underlying mechanism remains elusive. To investigate whether moxibustion can ameliorate OA by influencing the metabolic processes and to elucidate specific mechanisms involved. C57BL/6J WT mice were randomly assigned one of three groups: SHAM group, ACLT ACLT+M group. In underwent treatment at acupoints Shenshu (BL23) Zusanli (ST36) continuous period 28 days,...
Background: A range of imaging modalities have reported Alzheimer’s disease-related abnormalities in individuals experiencing subjective cognitive decline (SCD). However, there has been no consistent local abnormality identified across multiple neuroimaging for SCD. Objective: We aimed to investigate the convergent alterations amyloid-β (Aβ) deposition, glucose metabolism, and resting-state functional MRI (RS-fMRI) metrics Methods: Fifty SCD patients (66.4±5.7 years old, 19 men [38%]) 15...
Scaled Subprofile Model of Principal Component Analysis (SSM-PCA) is a multivariate statistical method and has been widely used in Positron Emission Tomography (PET). Recently, SSM-PCA applied to discriminate patients with Parkinson's disease healthy controls Amplitude Low Frequency Fluctuation (ALFF) from Resting-State Functional Magnetic Resonance Imaging (RS-fMRI). As RS-fMRI scans are more readily available than PET scans, it important investigate the intra- inter-scanner reliability...
Functional connectivity (FC) derived from resting-state functional magnetic resonance imaging has been widely applied to guide precise repetitive transcranial stimulation (rTMS). The left, right, and bilateral dorsolateral prefrontal cortices (DLPFC) have used as rTMS treatment target regions for autism spectrum disorder (ASD), albeit with moderate efficacy. Thus, we aimed develop an individualized localization method of ASD. We included 266 male ASDs 297 typically-developed controls (TDCs)...
Autism spectrum disorder (ASD) is a complex neurodevelopmental and its underlying neuroanatomical mechanisms still remain unclear. The scaled subprofile model of principal component analysis (SSM-PCA) data-driven multivariate technique for capturing stable disease-related spatial covariance pattern. Here, SSM-PCA innovatively applied to obtain robust ASD-related gray matter volume pattern associated with clinical symptoms. We utilized T1-weighted structural MRI images (sMRI) 576 subjects...
Background The degeneration of the corticospinal tract (CST) in chronic stroke has been widely described using diffusion tensor imaging and correlates with extent motor deficits. However, only a few studies have reported early distal CST during acute stage pathological changes not described. Purpose To study microstructural along beyond ischemic lesion kurtosis (DKI). Study Type Prospective. Population In all, 48 patients (26 males, 22 females; mean age 58.27 ± 12.89 years) stroke. Sequence...
Human and animal studies on brain functions in subjects with autism spectrum disorder have confirmed the aberrant organization of functional networks. However, little is known about neural features underlying these impairments. Using community structure analyses (recruitment integration), current study explored network individuals from one database (101 120 healthy controls) tested replicability an independent (50 74 controls). Additionally, divided into different age groups subgroups. As...
The importance of white matter injury induced by diabetes in stroke severity and prognosis is largely unknown. We aimed to investigate the relationship between diabetes-related beyond lesions with acute neurological deficits clinical outcome after stroke. In total, 36 patients within 3–7 days onset were enrolled. Neurological on admission assessed National Institute Health Stroke Score, poor at 3 months was defined as modified Rankin score >2. White tracts compared diabetic non-diabetic...