A5057647448- Chronic Obstructive Pulmonary Disease (COPD) Research
- Gastric Cancer Management and Outcomes
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Lung Cancer Treatments and Mutations
- Pelvic floor disorders treatments
- Liver Disease and Transplantation
- Reproductive System and Pregnancy
- Acute Ischemic Stroke Management
- RNA modifications and cancer
- Appendicitis Diagnosis and Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Microscopic Colitis
- Nasal Surgery and Airway Studies
- Inflammatory Bowel Disease
- Hepatocellular Carcinoma Treatment and Prognosis
- Gynecological conditions and treatments
- Heart Failure Treatment and Management
- Cancer Mechanisms and Therapy
- Medicinal Plant Pharmacodynamics Research
China-Japan Friendship Hospital
2020-2025
Sir Run Run Shaw Hospital
2025
Zhejiang University
2025
Fudan University
2013-2024
Sanofi (China)
2024
Pudong Medical Center
2021-2024
Sichuan University
2024
West China Hospital of Sichuan University
2024
Wuhan University of Science and Technology
2024
China Pharmaceutical University
2024
Background Heart failure (HF) guidelines recommend routine testing for iron deficiency (ID) and, those with ID, intravenous if the left ventricular ejection fraction is <50%. Guideline adherence to these recommendations by cardiologists in China unknown. Methods and results An independent academic web-based survey was designed distributed via social networks across China. Overall, 1342 (median age 34 years, IQR 30–39, 51% women) from all provinces of completed this survey. More than half...
Neoadjuvant therapy followed by surgery is the recommended treatment for patients with locally advanced lung cancer. No studies have examined risk factors of postoperative pulmonary complications (PPCs) in this group patients. The addition immune checkpoint inhibitors (ICIs) can improve efficacy neoadjuvant therapy; however, it unknown whether ICIs will also increase PPC incidence. Thus, we conducted study to identify predictors PPCs. We reviewed database Sir Run Shaw Hospital, School...
The risk factors of bladder cancer recurrence after transurethral resection tumor (TURBt) were poorly understood, especially in Chinese population. This study evaluated the potential based on a population.A total 698 patients that received TURBt procedure our institute from 2000 to 2012 recruited this study. Clinical information was collected. followed up according schedule recommended by guideline.A 583 males (83.5%) and 115 females (16.5%) enrolled median follow-up duration 51.5 months....
Signal transducer and activator of transcription (STAT) is a unique protein family that binds to DNA plays vital role in regulating major physiological cellular processes. Seven STAT genes have been identified the human genome. Several studies suggest members be involved cancer development, progression, metastasis. However, predictive relationship between expression immune cell infiltration endometrial remains unknown.We explored prognosis using various databases. The STRING, GeneMANIA,...
Background. Ferroptosis is a recently described form of intentional cellular damage that iron-dependent and separate from apoptosis, necrosis, autophagy. It has been demonstrated to be adequately regulated by long noncoding RNAs (lncRNAs) in various cancers. However, the predictive profile ferroptosis-related lncRNAs (FRLs) endometrial carcinoma (EC) unknown. Herein, FRLs associated with uterine corpus (UCEC) prognosis were screened predict treatment response EC. Methods. Samples EC adjacent...
N6-methyladenosine (m6A) has been identified as the most common, abundant, and conserved internal transcriptional modification. Long noncoding RNAs (lncRNAs) are consisting of more than 200 nucleotides, expression various lncRNAs may affect cancer prognosis. The impact m6A-associated on uterine corpus endometrial carcinoma (UCEC) prognosis is unknown.In this study, UCEC prognosis-related m6A were screened, bioinformatics analysis was performed, experimental validation conducted. Endometrial...
Loki zupa formula is kind of a traditional medicines which used to treat airway diseases, especially those caused by abnormal phlegm, such as cough, asthma and chronic bronchitis. The study aim was explore the anti-inflammatory anti-remodeling effects using cigarette-smoke induced rat model obstructive pulmonary disease.The rats were divided into five groups: normal group, LZ 4 g/kg LZ8g/kg positive control group. Rats exposed cigarette smoke for 24 weeks induce COPD model. Lung function...
Objective. To investigate the profiles of vaginal microbiome in patients with endometrial hyperplasia and to explore potential value diagnosis hyperplasia. Materials/Methods. 26 suffering from abnormal uterine bleeding (AUB) thickened endometrium revealed by transvaginal ultrasonography were enrolled. Based on pathology, 12 classified as Veh group 14 proliferative Vne group. The samples collected for presence microbial DNA high-throughput next-generation sequencing 16S rRNA gene. α-diversity...
Inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are characterised by complex deficiencies of the mucosal antimicrobial barrier. Different epithelial secreted peptides protect surface regulate gut luminal microbial community while ensuring a beneficial homeostasis. Disrupting this balance an excessive or dysregulated immune response also results in so-called "dysbiosis" but cause consequence is still unclear. Independent causality debate, decreased complexity...
Hypertrophic cardiomyopathy (HCM), identified as a primary cause of sudden cardiac death (SCD), intertwines with pulmonary hypertension (PH) to amplify cardiovascular morbidity. This complex synergy poses significant therapeutic challenges due the absence drugs specifically targeting their concurrent manifestation. study seeks unravel molecular intricacies linking HCM and PH, aiming lay groundwork for targeted interventions.
Cell-free DNA (cfDNA) has attracted increasing attention as a promising biomarker in liquid biopsy due to its crucial role disease diagnosis.
Background:Whether ischemic stroke per se, rather than older age or additional comorbidities, accounts for the adverse prognosis of heart failure (HF) is uncertain. The present study examineed intrinsic association with outcomes in a propensity-matched cohort.