A5079877026- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Advancements in Transdermal Drug Delivery
- Food Allergy and Anaphylaxis Research
- Skin and Cellular Biology Research
- Skin Protection and Aging
- Transgenic Plants and Applications
- Acne and Rosacea Treatments and Effects
- melanin and skin pigmentation
- Plant Reproductive Biology
- Stress Responses and Cortisol
- Wnt/β-catenin signaling in development and cancer
- Exercise and Physiological Responses
- Contact Dermatitis and Allergies
- Neuroendocrine regulation and behavior
- Autism Spectrum Disorder Research
- Bee Products Chemical Analysis
- Advanced Sensor and Energy Harvesting Materials
- Cell Adhesion Molecules Research
- Photodynamic Therapy Research Studies
- Asthma and respiratory diseases
- Lipid metabolism and biosynthesis
- Hair Growth and Disorders
- Urticaria and Related Conditions
- Antimicrobial Peptides and Activities
San Francisco VA Medical Center
2010-2024
University of California, San Francisco
2010-2024
Northern California Institute for Research and Education
2020-2024
San Francisco VA Health Care System
2021-2023
University of California System
2010
Veterans Health Administration
2010
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease associated with epidermal barrier disruption and intense systemic inflammation. Previously, we showed that exosomes derived from human adipose tissue-derived mesenchymal stem cells (ASC-exosomes) attenuate AD-like symptoms by reducing multiple inflammatory cytokine levels. Here, investigated ASC-exosomes’ effects on skin restoration analyzing protein lipid contents. We found subcutaneous injection of ASC-exosomes in an...
Until recently, atopic dermatitis (AD) has been linked to Th1/Th2 cell dysregulation. But now, the opinion that inflammation in AD results from a convergence of inherited and acquired insults cutaneous permeability barrier, with variable contributions abnormalities innate/adaptive immunity, is becoming increasingly accepted. Current therapy however, still largely directed towards ameliorating immunologically triggered inflammation, rather than correcting barrier abnormality. In this article,...
Abstract Pigmentation evolved in ancestral humans to protect against toxic, ultraviolet B irradiation, but the question remains: “what is being protected?” Because with dark pigmentation display a suite of superior epidermal functions comparison their more lightly pigmented counterparts, we hypothesized and provided evidence that Africa support cutaneous function. our prior clinical studies also showed restoration competent barrier dampens inflammation, resistance inflammation could have...
Autism, a childhood behavioral disorder, belongs to large suite of diseases, collectively referred as autism spectrum disorders (ASD). Though multifactorial in etiology, approximately 10% ASD are associated with atopic dermatitis (AD). Moreover, prevalence increases further AD severity worsens, though these share no common causative mutations. We assessed here the link between two standard, valproic acid mouse model ASD. In prior studies, there was evidence skin involvement, but we...