A5074777196- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Dental Implant Techniques and Outcomes
- Orthopaedic implants and arthroplasty
- Facial Trauma and Fracture Management
- Calcium Carbonate Crystallization and Inhibition
- Additive Manufacturing and 3D Printing Technologies
- Periodontal Regeneration and Treatments
- biodegradable polymer synthesis and properties
- Dental materials and restorations
- Magnesium Oxide Properties and Applications
- Mesenchymal stem cell research
- Endodontics and Root Canal Treatments
- Medical and Biological Sciences
- Bone health and treatments
- MXene and MAX Phase Materials
- Layered Double Hydroxides Synthesis and Applications
- Graphene and Nanomaterials Applications
- Advanced ceramic materials synthesis
- Spaceflight effects on biology
- Tissue Engineering and Regenerative Medicine
- Planetary Science and Exploration
- Electrospun Nanofibers in Biomedical Applications
- Radiopharmaceutical Chemistry and Applications
- Marine Biology and Environmental Chemistry
Ministry of Health of the Russian Federation
2016-2025
P.A. Hertzen Moscow Oncology Research Institute
2014-2025
Medical Radiological Research Center
2016-2021
Baikov Institute of Metallurgy and Materials Science
2017
Pirogov Russian National Research Medical University
2017
Federal Medical-Biological Agency
2008
Theratechnologies (Canada)
2008
The development of specific MRI criteria to monitor the implantation process may provide valuable information individual tissue response. Using and histological methods, biointegration carbon-carbon (C-C) composites into subcutaneous tissues BDF1 mice their biocompatibility were investigated. study focused on autopsy specimens containing C-C composite implants, both uncoated coated with synthetic hydroxyapatite (Ca-P) via electrodeposition or detonation techniques, assessed at 6 12 weeks...
Sr2+-substituted β-tricalcium phosphate (β-TCP) powders were synthesized using the mechano-chemical activation method with subsequent pressing and sintering to obtain ceramics. The concentration of Sr2+ in samples was 0 (non-substituted TCP, as a reference), 3.33 (0.1SrTCP), 16.67 (0.5SrTCP) mol.% expected Ca3(PO4)2, Ca2.9Sr0.1(PO4)2, Ca2.5Sr0.5(PO4)2 formulas, respectively. chemical compositions confirmed by energy-dispersive X-ray spectrometry (EDX) inductively coupled plasma optical...
Nanocrystalline 3 mol% yttria-tetragonal zirconia polycrystal (3Y-TZP) ceramic powder containing 5 wt.% Al2O3 with 64 m2/g specific area was synthesized through precipitation method. Different amounts of Co (0–3 mol%) were introduced into powders, and materials obtained by heat treatment in the air for 2 h at 1350–1550 °C. The influence addition on sintering temperature, phase composition, microstructure, mechanical biomedical properties composite materials, resolution digital light...
Powders based on β-tricalcium phosphate (β-TCP) containing sulphate groups at up to 12.0 mol.% were synthesised by chemical precipitation from aqueous solutions. The obtained materials characterised X-ray phase analysis, Fourier transform infrared spectroscopy, measurement of specific surface area, scanning electron microscopy, energy dispersive synchronous thermal mass spectra investigations and biological assays. It was established that during the synthesis, lose in course heat treatment...
The development of magnesium calcium phosphate bone cements (MCPCs) has garnered substantial attention. MCPCs are bioactive and biodegradable have appropriate mechanical antimicrobial properties for use in reconstructive surgery. In this study, the cement powders based on a (Ca + Mg)/P = 2 system doped with Zn2+ at 0.5 1.0 wt.% were obtained investigated. After mixing liquid, structural phase composition, morphology, chemical structure, setting time, compressive strength, degradation...
Bones are the fourth most frequent site of metastasis from malignant tumors, including breast cancer, prostate melanoma, etc. The bioavailability bone tissue for chemotherapy drugs is extremely low. This requires a search new approaches targeted drug delivery to tumor growth zone after surgery treatment. aim this work was develop method octacalcium phosphate (OCP) graft functionalization with cytostatic cisplatin provide local release its therapeutic concentrations into defect. OCP porous...
Human platelet lysate (HPL) is a promising alternative to fetal calf serum (FCS) for the expansion of adipose tissue mesenchymal stromal cells (AT-MSCs) translational medicine applications. However, some biological effects HPL are still be elucidated. We aimed compare complex characteristics, such as cell morphology, proliferative activity, differentiation potential, and especially monolayer recovery, DNA integrity, gene expression pattern, between AT-MSCs cultured with or FCS. Primary...
The development of magnesium calcium phosphate bone cements (MCPCs) have garnered big attention. MCPCs are bioactive and biodegradable appropriate mechanical antimicrobial properties for use in reconstructive surgery. In this study, the cement powders based on a (Ca + Mg)/P = 2 system doped with Zn2+ at 0.5 1.0 wt.% were obtained investigated. After mixing liquid, structural phase composition, morphology, chemical structure, setting time, compressive strength, degradation behavior,...
Despite a long period of application metal implants, carbon-carbon medical composites are also widely used for bone defect prosthesis in surgery, dentistry, and oncology. Such implants might demonstrate excellent mechanical properties, but their biocompatibility integration efficiency into the host should be improved. As method enhancing, electrophoretic deposition fine-dispersed hydroxyapatite (HAp) on porous carbon substrates recommended. With electron microscopy, energy dispersion X-ray...
The composite cements based on simple mixtures brishite and apatite with ratio 70/30, 50/50, 30/70 were developed. processes of phase formation, microstructure mechanical properties studied. kinetics degradation in simulated body fluid depending the materials composition was carried out. biological test vitro performed using MTT-test human fibroblast immortalized (hFB) cell line osteosarcoma MG-63. didn't have acute cytoxicity possessed surface matrix properties. It determined that both...